Patents by Inventor Satsuki Mochizuki

Satsuki Mochizuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human antibody against aggrecanase-type ADAMTS species for therapeutics of aggrecanase-related diseases
    Patent number: 10640573
    Abstract: The present invention provides an antibody that specifically binds to human aggrecanase, and inhibits enzymatic activity of the human aggrecanase. In one embodiment, aggrecanase is ADAMTS4. In one embodiment, the antibody recognizes a particular epitope in human ADAMTS4, and inhibits not only aggrecanase activity of human ADAMTS4 but also aggrecanase activity of human ADAMTS5. In addition, the present invention also provides use of said antibody in the prophylaxis or treatment of the progression of arthritis.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: May 5, 2020
    Assignees: GeneFrontier Corporation, Keio University
    Inventors: Akira Miyakoshi, Mikiko Nakamura, Kanehisa Kojoh, Satsuki Mochizuki, Yasunori Okada
  • Anti-ADAM28 antibody for treating cancer
    Patent number: 10556967
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: February 11, 2020
    Assignees: GENEFRONTIER CORPORATION, KEIO UNIVERSITY
    Inventors: Akira Miyakoshi, Rena Matsumoto, Shizue Katoh, Yuki Hayami, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada
  • HUMAN ANTIBODY AGAINST AGGRECANASE-TYPE ADAMTS SPECIES FOR THERAPEUTICS OF AGGRECANASE-RELATED DISEASES
    Publication number: 20190233541
    Abstract: The present invention provides an antibody that specifically binds to human aggrecanase, and inhibits enzymatic activity of the human aggrecanase. In one embodiment, aggrecanase is ADAMTS4. In one embodiment, the antibody recognizes a particular epitope in human ADAMTS4, and inhibits not only aggrecanase activity of human ADAMTS4 but also aggrecanase activity of human ADAMTS5. In addition, the present invention also provides use of said antibody in the prophylaxis or treatment of the progression of arthritis.
    Type: Application
    Filed: October 5, 2018
    Publication date: August 1, 2019
    Applicants: GeneFrontier Corporation, Keio University
    Inventors: Akira MIYAKOSHI, Mikiko NAKAMURA, Kanehisa KOJOH, Satsuki MOCHIZUKI, Yasunori OKADA
  • Anti-human membrane-type ADAM28 antibody
    Patent number: 10329358
    Abstract: The present invention provides an antibody having an activity to specifically bind to human membrane-anchored form ADAM28 at an epitope in a region of the 524th-659th amino acids in the amino acid sequence shown in SEQ ID NO: 2. In addition, the present invention provides a drug delivery vehicle for delivering a drug to a cell or tissue that expresses human membrane-anchored form ADAM28, which contains the antibody.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 25, 2019
    Assignees: GeneFrontier Corporation, KEIO UNIVERSITY
    Inventors: Akira Miyakoshi, Kanehisa Kojoh, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada
  • ANTI-ADAM28 ANTIBODY FOR TREATING CANCER
    Publication number: 20180155448
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Application
    Filed: November 16, 2017
    Publication date: June 7, 2018
    Applicants: GENEFRONTIER CORPORATION, KEIO UNIVERSITY
    Inventors: Akira MIYAKOSHI, Rena MATSUMOTO, Shizue KATOH, Yuki HAYAMI, Satsuki MOCHIZUKI, Masayuki SHIMODA, Yasunori OKADA
  • ANTI-HUMAN MEMBRANE-TYPE ADAM28 ANTIBODY
    Publication number: 20180044435
    Abstract: The present invention provides an antibody having an activity to specifically bind to human membrane-anchored form ADAM28 at an epitope in a region of the 524th-659th amino acids in the amino acid sequence shown in SEQ ID NO: 2. In addition, the present invention provides a drug delivery vehicle for delivering a drug to a cell or tissue that expresses human membrane-anchored form ADAM28, which contains the antibody.
    Type: Application
    Filed: March 4, 2016
    Publication date: February 15, 2018
    Applicants: GeneFrontier Corporation, KEIO UNIVERSITY
    Inventors: Akira MIYAKOSHI, Kanehisa KOJOH, Satsuki MOCHIZUKI, Masayuki SHIMODA, Yasunori OKADA
  • Anti-ADAM28 antibody for treating cancer
    Patent number: 9845364
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: December 19, 2017
    Assignees: GeneFrontier Corporation, Keio University
    Inventors: Akira Miyakoshi, Rena Matsumoto, Shizue Katoh, Yuki Hayami, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada
  • HUMAN ANTIBODY AGAINST AGGRECANASE-TYPE ADAMTS SPECIES FOR THERAPEUTICS OF AGGRECANASE-RELATED DISEASES
    Publication number: 20160304622
    Abstract: The present invention provides an antibody that specifically binds to human aggrecanase, and inhibits enzymatic activity of the human aggrecanase. In one embodiment, aggrecanase is ADAMTS4. In one embodiment, the antibody recognizes a particular epitope in human ADAMTS4, and inhibits not only aggrecanase activity of human ADAMTS4 but also aggrecanase activity of human ADAMTS5. In addition, the present invention also provides use of said antibody in the prophylaxis or treatment of the progression of arthritis.
    Type: Application
    Filed: October 14, 2014
    Publication date: October 20, 2016
    Applicants: GeneFrontier Corporation, Keio University
    Inventors: Akira MIYAKOSHI, Mikiko NAKAMURA, Kanehisa KOJOH, Satsuki MOCHIZUKI, Yasunori OKADA
  • ANTI-ADAM28 ANTIBODY FOR TREATING CANCER
    Publication number: 20150274840
    Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.
    Type: Application
    Filed: October 1, 2013
    Publication date: October 1, 2015
    Inventors: Akira Miyakoshi, Rena Matsumoto, Shizue Katoh, Yuki Hayami, Satsuki Mochizuki, Masayuki Shimoda, Yasunori Okada