Abstract: The present invention is a handle grip comprising a twist throttle with an integrated hydraulic master cylinder directed to vehicle throttle and brake or clutch controls and suitable for mounting and use on motorcycle handle bar wherein the operator selectively twists the handle grip in one direction to retract a throttle cable and in the opposite direction to release the throttle cable and activate a hydraulic master cylinder capable of providing hydraulic fluid to a hydraulically activated mechanism on the vehicle. A helical cam surface within the twist grip mechanism guides centrally positioned throttle and hydraulic cam followers within an inner stem cylinder bore forcing the followers longitudinally within the bore to activate the hydraulics or throttle. The pitch of the helical cam surface defines the distance of grip rotation and the twisting torque required to move the followers predetermined distances within the stem bore to provide sufficient activation force.