Abstract: Provided herein are systems and methods for an application connector (also referred to as a reverse extract, transform, load (ETL) connector) in a database system. For example, a method includes retrieving, by at least one hardware processor, configuration information associated with an application executing on an application server. The configuration information identifies a query. The method further includes executing the query to obtain a query result. The method further includes performing an update of the application at the application server using the query result.

Abstract: Provided herein are systems and methods for an application connector (also referred to as a reverse extract, transform, load (ETL) connector) in a database system. For example, a method includes executing at a first computing node, a user-defined function (UDF) to invoke an application programming interface (API) during an API call. The API is invoked via a second computing node that is external to the first computing node. The method further includes retrieving during the API call, data stored in a storage device shared by a plurality of applications. The method further includes updating using an integration function of the API, at least one application of the plurality of applications based on the data.

Abstract: Provided herein are systems and methods for an application connector (also referred to as a reverse extract, transform, load (ETL) connector) in a database system. For example, a method includes retrieving an application connector corresponding to an application of a plurality of available applications. The application connector includes connector configuration information and connector code. A user-defined query is detected within the connector configuration information. The user-defined query is executed to obtain a query result. The query result is based on data stored in a storage device shared by the plurality of applications. The connector code of the application connector is executed to perform an update of the application, the update based on the query result.

Abstract: This invention relates to a convenient and improved process for preparation of glatiramer acetate (copolymer-1) of pharmaceutical grade. The process involves polymerizing N-carboxyanhydrides of tyrosine, alanine, y-benzyl glutamate and ?-N-trifluoroacetyllysine in dioxane with diethylamine as initiator to afford protected copolymer-1. Treatment with hydrogen bromide in acetic acid at 35° C. for 3-5 h cleaves benzyl group to produce trifluoroacetyl copolymer-1. The trifluoroacetyl copolymer-1 is washed with an organic solvent to remove reactive benzyl bromide generated during debenzylation. Deprotection with aqueous piperidine, followed by dialysis offers glatiramer acetate (copolymer-1) of Molecular weight 5000-9000 daltons.

Abstract: This invention relates to a convenient and improved process for preparation of glatiramer acetate (copolymer-1) of pharmaceutical grade. The process involves polymerizing N-carboxyanhydrides of tyrosine, alanine, y-benzyl glutamate and &egr;-N-trifluoroacetyllysine in dioxane with diethylamine as initiator to afford protected copolymer-1. Treatment with hydrogen bromide in acetic acid at 35° C. for 3-5 h cleaves benzyl group to produce trifluoroacetyl copolymer-1. The trifluoroacetyl copolymer-1 is washed with an organic solvent to remove reactive benzyl bromide generated during debenzylation. Deprotection with aqueous piperidine, followed by dialysis offers glatiramer acetate (copolymer-1) of Molecular weight 5000-9000 daltons.