Patents by Inventor Satyanarayana Majeti
Satyanarayana Majeti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11357250Abstract: The invention encompasses compositions and methods for effectively treating and/or preventing diabetes and/or obesity. This is accomplished by totally addressing the multiple mechanisms that lead to such conditions. The invention includes compositions comprising a combination of agents that effectively suppress, regulate or interfere with the various biochemical processes and mechanisms that lead to diabetes and obesity.Type: GrantFiled: August 11, 2017Date of Patent: June 14, 2022Assignee: Summit Innovation Labs LLCInventors: Haile Mehansho, Satyanarayana Majeti, Ghebre Egziabher Tzeghai
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Patent number: 11344575Abstract: The invention encompasses compositions and methods for effectively interfering, reducing and preventing conversion of vascular smooth muscle cells (VSMCs) and circulating stem cells to osteoblastic bone-like cells, thereby reducing and/or preventing vascular calcification (VC) or calcium mineral (hydroxyapatite) deposition in the vasculature. The severity and extent of calcification in the major arteries reflect atherosclerotic plaque burden and strongly predict cardiovascular morbidity and mortality.Type: GrantFiled: July 13, 2017Date of Patent: May 31, 2022Assignee: Summit Innovation Labs, LLCInventors: Satyanarayana Majeti, Haile Mehansho, Ghebre Egziabher Tzeghai
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Patent number: 11039636Abstract: The invention encompasses compositions and methods for effectively treating and/or preventing the development and/or progression of osteoporosis and related disorders such as osteoarthritis and rheumatoid arthritis, and for promoting overall bone and joint health. This is accomplished by addressing multiple key mechanisms that lead to such disorders. The invention includes compositions comprising a combination of agents having biological activities that effectively suppress, regulate or interfere with the various key biochemical processes and mechanisms that increase the risk for development and/or progression of osteoporosis. The present compositions and methods simultaneously promote bone formation and reduce bone resorption by (a) stimulating osteoblast formation and osteogenesis; (b) suppressing adipocyte differentiation; (c) inhibiting osteoclast formation; and (d) increasing apoptosis of osteoclasts.Type: GrantFiled: May 13, 2019Date of Patent: June 22, 2021Assignee: Summit Innovation Labs, LLCInventors: Ghebre Egziabher Tzeghai, Haile Mehansho, Satyanarayana Majeti
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Patent number: 11007171Abstract: The invention encompasses compositions and methods for effectively treating and/or preventing the development and/or progression of osteoarthritis and rheumatoid arthritis and for promoting overall joint health. This is accomplished by totally addressing the key multiple biochemical processes and mechanisms that lead to such disorders. The invention includes compositions comprising a combination of natural agents that safely and effectively suppress, regulate or interfere with the various biochemical processes and mechanisms that increase the risk for or lead to the development and/or progression of OA and RA.Type: GrantFiled: July 31, 2018Date of Patent: May 18, 2021Assignee: Summit Innovation Labs, LLCInventors: Haile Mehansho, Satyanarayana Majeti, Ghebre Egziabher Tzeghai
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Publication number: 20190261668Abstract: The invention encompasses compositions and methods for effectively treating and/or preventing the development and/or progression of osteoporosis and related disorders such as osteoarthritis and rheumatoid arthritis, and for promoting overall bone and joint health. This is accomplished by addressing multiple key mechanisms that lead to such disorders. The invention includes compositions comprising a combination of agents having biological activities that effectively suppress, regulate or interfere with the various key biochemical processes and mechanisms that increase the risk for development and/or progression of osteoporosis. The present compositions and methods simultaneously promote bone formation and reduce bone resorption by (a) stimulating osteoblast formation and osteogenesis; (b) suppressing adipocyte differentiation; (c) inhibiting osteoclast formation; and (d) increasing apoptosis of osteoclasts.Type: ApplicationFiled: May 13, 2019Publication date: August 29, 2019Applicant: Summit Innovation Labs LLCInventors: Ghebre Egziabher Tzeghai, Haile Mehansho, Satyanarayana Majeti
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Publication number: 20190015448Abstract: The invention encompasses compositions and methods for effectively treating and/or preventing osteoporosis and related disorders such as osteoarthritis and rheumatoid arthritis, and for promoting overall bone and joint health. This is accomplished by totally addressing the multiple mechanisms that lead to such disorders. The invention includes compositions comprising a combination of agents that effectively suppress, regulate or interfere with the various biochemical processes and mechanisms that increase the risk for development of osteoporosis. The present compositions and methods simultaneously promote bone formation and reduce bone resorption by (a) stimulating osteoblast formation and osteogenesis; (b) suppressing adipocyte differentiation; (c) inhibiting osteoclast formation; and (d) increasing apoptosis of osteoclasts.Type: ApplicationFiled: February 28, 2018Publication date: January 17, 2019Applicant: Summit Innovation Labs LLCInventors: Ghebre Egziabher Tzeghai, Satyanarayana Majeti, Haile Mehansho
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Publication number: 20190015384Abstract: The invention encompasses compositions and methods for effectively treating and/or preventing the development and/or progression of osteoarthritis and rheumatoid arthritis and for promoting overall joint health. This is accomplished by totally addressing the key multiple biochemical processes and mechanisms that lead to such disorders. The invention includes compositions comprising a combination of natural agents that safely and effectively suppress, regulate or interfere with the various biochemical processes and mechanisms that increase the risk for or lead to the development and/or progression of OA and RA.Type: ApplicationFiled: July 31, 2018Publication date: January 17, 2019Applicant: Summit Innovation Labs LLCInventors: Haile Mehansho, Satyanarayana Majeti, Ghebre Egziabher Tzeghai
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Publication number: 20180042962Abstract: The invention encompasses compositions and methods for effectively interfering, reducing and preventing conversion of vascular smooth muscle cells (VSMCs) and circulating stem cells to osteoblastic bone-like cells, thereby reducing and/or preventing vascular calcification (VC) or calcium mineral (hydroxyapatite) deposition in the vasculature. The severity and extent of calcification in the major arteries reflect atherosclerotic plaque burden and strongly predict cardiovascular morbidity and mortality.Type: ApplicationFiled: July 13, 2017Publication date: February 15, 2018Applicant: Summit Innovation Labs LLCInventors: Satyanarayana Majeti, Haile Mehansho, Ghebre Egziabher Tzeghai
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Patent number: 9458414Abstract: A cleaning or personal care composition containing at least one of 1,4-pentanediol and a ketal alcohol of formula (1) wherein R2 is hydrogen or C1-3 alkyl, each R3, R4, and R5 is independently hydrogen or C1-6 alkyl, R6 and R7 are each independently hydrogen or C1-6 alkyl, a=0-3, and b=0-1. R2 is hydrogen or C1-3 alkyl, each R3, R4, and R5 is independently hydrogen or C1-6 alkyl, each R6 and R7 is independently hydrogen, C1-6 alkyl optionally substituted with at least one hydroxyl groups, a=1-6, and b=0-2.Type: GrantFiled: September 20, 2013Date of Patent: October 4, 2016Assignee: GFBIOCHEMICALS LIMITEDInventors: Lee R. Rieth, Satyanarayana Majeti, Erich J. Molitor
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Publication number: 20150252302Abstract: A cleaning or personal care composition containing at least one of 1,4-pentanediol and a ketal alcohol of formula (1) wherein R2 is hydrogen or C1-3 alkyl, each R3, R4, and R5 is independently hydrogen or C1-6 alkyl, R6 and R7 are each independently hydrogen or C1-6 alkyl, a=0-3, and b=0-1. R2 is hydrogen or C1-3 alkyl, each R3, R4, and R5 is independently hydrogen or C1-6 alkyl, each R6 and R7 is independently hydrogen, C1-6 alkyl optionally substituted with at least one hydroxyl groups, a=1-6, and b=0-2.Type: ApplicationFiled: September 20, 2013Publication date: September 10, 2015Applicant: SEGETIS, INC.Inventors: Lee R. Rieth, Satyanarayana Majeti, Erich J. Molitor
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Publication number: 20110274728Abstract: Various compositions and methods are provided to alleviate one or more symptoms associated with hyposalivation or xerostomia. Preferred compositions and methods employ one or more plant extracts and/or a proanthocyanidin at a concentration effective to reduce or eliminate the symptoms. Especially preferred extracts are isolated from a fruit and/or seed (e.g., grape, cranberry, blue berry, black berry, etc.), and where a second extract is present, such extract is preferably isolated from a citrus fruit (e.g., lemon, orange, lime, grapefruit, tangerine, mandarin orange, ugli fruit, etc.).Type: ApplicationFiled: November 13, 2009Publication date: November 10, 2011Inventors: David Hamlin, Satyanarayana Majeti, Zbigniew Pietrzkowski
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Publication number: 20080072389Abstract: Disclosed is a method for providing an oral care benefit by combining the use of an oral carc composition with an electric toothbrush having an electrically powered element disposed thereon. In particular methods are described for using an electric toothbrush comprising a light emitting element, with oral care compositions to provide tooth whitening and stain removal.Type: ApplicationFiled: August 20, 2007Publication date: March 27, 2008Inventors: Chanchal Ghosh, Satyanarayana Majeti, Aleksey Pinyayev, John Chan, Alan Willey
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Publication number: 20070248634Abstract: A tooth whitening substance formed into a thin layer is provided. The tooth whitening substance includes a polyox resin and a tooth whitening active. The polyox resin adheres the thin layer to a plurality of teeth for a sufficient time to allow the tooth whitening active to act upon the plurality of teeth.Type: ApplicationFiled: June 29, 2007Publication date: October 25, 2007Inventors: Paul Sagel, Robert Dirksing, Frederick Rohman, Satyanarayana Majeti, Elizabeth Reno
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Publication number: 20070166244Abstract: Disclosed are compositions for delivering one or more oral care substances to the oral cavity, comprising: (a) a silicone pressure sensitive adhesive selected from a silicone/resin copolymer with silicon-bonded hydroxyl radicals, a silicone/resin copolymer with endcapped silicon-bonded hydroxyl radicals and mixtures thereof; (b) a plasticizing material; (c) a water-soluble bioadhesive polymer; (d) a hydrophilic surfactant, and (e) at least one oral care substance. The silicone/resin copolymer is prepared by polycondensing a silanol endblocked polydialkylsiloxane and a hydroxyl endblocked silicate resin. The polycondensation product may be further reacted with a trialkylsilyl endcapping agent to reduce the number of hydroxyl radicals in the polymer. Further disclosed are methods of using these compositions, such as for teeth bleaching and whitening applications.Type: ApplicationFiled: January 19, 2006Publication date: July 19, 2007Inventors: Chanchal Ghosh, Stephen Kovacs, Satyanarayana Majeti
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Patent number: 7166235Abstract: Disclosed are compositions and methods for treating and modifying surfaces and for enhancing delivery of active agents to surfaces treated therewith, wherein the compositions comprise siloxane polymers functionalized with pendant moieties comprising two or more anionic groups, at least one anionic group being a carboxy group. When applied to a suitable surface, the present composition forms a substantially hydrophobic coating of the anionic functionalized siloxane polymer on the treated surface. These polymers effectively deposit on surfaces that have cationic sites, which are capable of forming bonds or linkages with the anionic groups of the polymer. The treated surface becomes hydrophobic due to the deposition of the anionic functionalized siloxane polymer, which then imparts a variety of end use benefits to that surface such as ease of cleaning, soil release, stain removal and prevention, conditioning, etc.Type: GrantFiled: May 6, 2003Date of Patent: January 23, 2007Assignee: The Procter & Gamble CompanyInventors: Satyanarayana Majeti, Elizabeth Ann Brown Reno, Stephen Andras Kovacs
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Patent number: 7163674Abstract: Disclosed are personal care or cosmetic compositions comprising a dicarboxy functionalized polyorganosiloxane and methods for the cleaning or the treatment of hair or skin and for enhancing delivery of active agents to hair or skin with the compositions. Said personal care or cosmetic compositions can be formulated in a wide variety of types of products for the skin and/or hair (or, more generally, keratin) such as mousses, gels (in particular hair dressing gels), conditioners, hair dressing formulations or to aid comb-through of hair, rinsing formulae, hand and body lotions, skin moisturizing products, skin cleansing or disinfecting compositions, shower gels, toilet milks, cream foundations, make-up removal compositions, sun and ultraviolet radiation protection lotions, creams or gels, skin care creams, anti-age preparations, anti-acne preparations, local analgesics, mascaras, deodorants, antiperspirants, lipsticks and other compositions of the same type.Type: GrantFiled: May 6, 2003Date of Patent: January 16, 2007Assignee: The Procter & Gamble CompanyInventors: Satyanarayana Majeti, Elizabeth Ann Brown Reno, Stephen Andras Kovacs, Philippe Olier
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Publication number: 20060257822Abstract: Disclosed is a method for providing an oral care benefit by combining the use of an oral care composition with an electric toothbrush having an electrically powered element disposed thereon. In particular methods are described for using an electric toothbrush comprising a light emitting element, with oral care compositions to provide tooth whitening and stain removal.Type: ApplicationFiled: July 18, 2006Publication date: November 16, 2006Inventors: Chanchal Ghosh, Satyanarayana Majeti, Aleksey Pinyayev, John Chan, Alan Willey
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Patent number: 7025950Abstract: Disclosed are compositions and methods for treating and modifying surfaces and for enhancing delivery of active agents to surfaces treated with the compositions, which comprise siloxane polymers functionalized with pendant moieties comprising anionic groups, specifically carboxylic acid groups. When applied to a suitable surface, the present composition comprising the carboxy functionalized siloxane polymers forms a substantially hydrophobic coating on the treated surface. These polymers effectively deposit on surfaces that have cationic sites, which are capable of forming bonds or linkages with the anionic groups of the polymer. The treated surface becomes hydrophobic due to the deposition of the carboxy functionalized siloxane polymer, which then imparts a variety of end use benefits to that surface such as ease of cleaning, stain removal and prevention, whitening, etc.Type: GrantFiled: May 6, 2003Date of Patent: April 11, 2006Assignee: The Procter & Gamble CompanyInventors: Satyanarayana Majeti, Elizabeth Ann Brown Reno, Stephen Andras Kovacs, William Michael Glandorf, Philippe Olier
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Publication number: 20050238591Abstract: A tooth whitening substance formed into a thin layer is provided. The tooth whitening substance includes a polyox resin and a tooth whitening active. The polyox resin adheres the thin layer to a plurality of teeth for a sufficient time to allow the tooth whitening active to act upon the plurality of teeth.Type: ApplicationFiled: June 21, 2005Publication date: October 27, 2005Inventors: Paul Sagel, Robert Dirksing, Frederick Rohman, Satyanarayana Majeti, Elizabeth Reno
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Patent number: 6887836Abstract: Disclosed are home care compositions comprising a dicarboxy functionalized polyorganosiloxane and methods for treating and modifying surfaces and for enhancing delivery of active agents to surfaces treated with the compositions. Said home care compositions can be used particularly for cleaning, rinsing, care or treatment of industrial, domestic or communal hard surfaces, as well as textile article surfaces; they are targeted at conferring on the surfaces treated therewith benefits such as water repellency, soil release, stain resistance, anti-fogging, surface repair, anti-wrinkling, shine, lubrication and/or at improving the residuality, impact and or efficacy of active materials comprised in said compositions. The dicarboxy functionalized polyorganosiloxane can be present in the home care compositions at a concentration of from about 0.005% to 10% by weight, preferably from about 0.05% to 5% by weight.Type: GrantFiled: May 6, 2003Date of Patent: May 3, 2005Assignee: The Procter & Gamble CompanyInventors: Satyanarayana Majeti, Elizabeth Ann Brown Reno, Stephen Andras Kovacs, Philippe Olier