Abstract: The present disclosure relates to a portable insulin and vaccine storage device. The portable insulin and vaccine storage device comprises of a storage unit to store insulin and vaccine; a Peltier module for heating or cooling the storage unit; a heat sink capable of working as a heat exchanger to maintain temperature of the Peltier module; a radiator and fan for maintaining temperature of the storage unit; a control unit for controlling functioning of the portable insulin and vaccine storage device; and a power supply unit for powering the portable insulin and vaccine storage device. The present disclosure provides a device designed to function under extreme weather conditions and being affordable, it is poised to bring about a positive change in the life of people afflicted with diabetes in South Asian countries and those who need to store insulin.