Patents by Inventor Saul C. Cherkofsky

Saul C. Cherkofsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalkyl-1H-pyrroles
    Patent number: 4477463
    Abstract: Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalkyl-1H-pyrroles, such as 4,5-bis(4-methoxyphenyl)-1-methyl-2-trifluoromethyl-1H-pyrrole, useful for treating arthritis and related diseases and/or relieving pain.
    Type: Grant
    Filed: May 10, 1982
    Date of Patent: October 16, 1984
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • 2-Substituted thio-4,5-diarylpyrimidines
    Patent number: 4438117
    Abstract: 2-Substitutedthio-4,5-diarylpyrimidines, such as 2-(1,1,2,2-tetrafluoroethylthio)-4,5-bis(4-methoxy-phenyl)pyrimidine useful for treating arthritis and/or alleviating pain.
    Type: Grant
    Filed: September 3, 1980
    Date of Patent: March 20, 1984
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 2-substituted-thio-4,5-dihydro-4,5-diaryl-1H-imidazoles
    Patent number: 4379159
    Abstract: Antiinflammatory 2-substituted-thio-4,5-dihydro-4,5-diaryl-1H-imidazoles, such as 4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(2,2,2-trifluoroethylthio)-1H-imidaz ole hydrochloride, useful for treatment of arthritis and related diseases.
    Type: Grant
    Filed: October 16, 1980
    Date of Patent: April 5, 1983
    Assignee: E. I. Du Pont de Nemours & Company
    Inventor: Saul C. Cherkofsky
  • Anti-inflammatory 4,5-diaryl-.alpha.-(polyfluoroalkyl)-1H-pyrrole-2-methanamines
    Patent number: 4335136
    Abstract: 4,5-Diaryl-.alpha.-(polyfluoroalkyl)-1H-pyrrole-2-methanamines such as 4,5-bis(4-fluorophenyl)-.alpha..alpha.-bis-(trifluoromethyl)-1H-pyrrole-2- methanamine, useful in treatment of inflammation.
    Type: Grant
    Filed: March 4, 1981
    Date of Patent: June 15, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 4,5-diaryl-2-arylthioimidazoles
    Patent number: 4330552
    Abstract: Antiinflammatory 4,5-diaryl-2-arylthioimidazoles, such as 4,5-bis(4-methoxyphenyl)-2-(4-chlorophenylthio)-1H-imidazole useful for treatment of arthritis and related diseases.
    Type: Grant
    Filed: November 6, 1980
    Date of Patent: May 18, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 2,3-diaryl-5-[2,2,2-trifluoro-1-(trifluoromethyl]ethyl-1H-pyrroles
    Patent number: 4318917
    Abstract: Antiinflammatory 2,3-diaryl-5-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]-1H-pyrroles, such as 2,3-bis(4-fluorophenyl)-5-[2,2,2-trifluoro-1-(trifluoromethyl)ethyl]-1H-py rrole, useful for treating arthritis and related diseases.
    Type: Grant
    Filed: May 14, 1981
    Date of Patent: March 9, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Saul C. Cherkofsky, George A. Boswell, Jr.
  • Antiinflammatory 5-substituted-2,3-diarylthiophenes
    Patent number: 4302461
    Abstract: Antiinflammatory 5-substituted-2,3-diarylthiophenes, such as 2,3-bis(4-fluorophenyl)-5-(trifluoromethylthio)thiophene, useful for treating arthritis and related diseases.
    Type: Grant
    Filed: June 20, 1980
    Date of Patent: November 24, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 4,5-diaryl-.alpha.,.alpha.-bis(polyfluoromethyl)-1H-pyrrole-2-methanethi ols
    Patent number: 4267190
    Abstract: 4,5-Diaryl-.alpha.,.alpha.-bis(polyfluoromethyl)-1H-pyrrole-2-methanethiols , such as 4,5-bis(4-fluorophenyl)-.alpha., .alpha.-bis(trifluoromethyl)-1H-pyrrole-2-methanethiol, useful in treatment of inflammation.
    Type: Grant
    Filed: April 18, 1980
    Date of Patent: May 12, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones
    Patent number: 4267184
    Abstract: Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones, useful for treating arthritis and related diseases.
    Type: Grant
    Filed: February 19, 1980
    Date of Patent: May 12, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 4,5-diaryl-2-nitroimidazoles
    Patent number: 4251535
    Abstract: Antiinflammatory 4,5-diaryl-2-nitroimidazoles, such as 4,5-bis(4-fluorophenyl)-2-nitroimidazole, useful for treating arthritis and related diseases.
    Type: Grant
    Filed: October 12, 1979
    Date of Patent: February 17, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
    Patent number: 4215135
    Abstract: Certain 2-substituted-1H-phenanthro[9,10-d]-imidazoles such as 2-[(1,1,2,2-tetrafluoroethyl)-sulfonyl]-1H-phenanthro[9,10-d]imidazole, are useful as antiinflammatory agents.
    Type: Grant
    Filed: June 8, 1979
    Date of Patent: July 29, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Saul C. Cherkofsky, Thomas R. Sharpe
  • Antiinflammatory 4,5-diaryl-2-nitroimidazoles
    Patent number: 4199592
    Abstract: Antiinflammatory 4,5-diaryl-2-nitroimidazoles, such as 4,5-bis(4-fluorophenyl)-2-nitroimidazole, useful for treating arthritis and related diseases.
    Type: Grant
    Filed: March 6, 1979
    Date of Patent: April 22, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Saul C. Cherkofsky
  • Antiinflammatory 2-substituted-dibenzo[2,3:6,7]oxepino[4,5-d]imidazoles
    Patent number: 4198421
    Abstract: Antiinflammatory 2-substituted-dibenzo[2,3:6,7]oxepino[4,5-d]imidazoles, such as 10-fluoro-2-[(1,1,2,2-tetrafluoroethyl)sulfonyl]-1H-dibenzo[2,3:6,7]oxepin o[4,5-d]imidazole, useful for treating arthritis and related diseases.
    Type: Grant
    Filed: November 30, 1978
    Date of Patent: April 15, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Saul C. Cherkofsky, Thomas R. Sharpe
  • Anti-inflammatory 4,5-diarly-2-(substituted-thio)imidazoles and their corresponding sulfoxides and sulfones
    Patent number: 4190666
    Abstract: Anti-inflammatory 4,5-diaryl-2-(substituted-thio)imidazols and their corresponding sulfoxides and sulfones useful for treating arthritis and related diseases.
    Type: Grant
    Filed: February 10, 1978
    Date of Patent: February 26, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Saul C. Cherkofsky, Thomas R. Sharpe
  • Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones
    Patent number: 4182769
    Abstract: Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones useful for treating arthritis and related diseases.
    Type: Grant
    Filed: January 5, 1978
    Date of Patent: January 8, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Saul C. Cherkofsky, Thomas R. Sharpe
  • Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones
    Patent number: 4159338
    Abstract: Antiinflammatory 4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones, such as, 4-(4-fluorophenyl)-2-(1,1,2,2-tetrafluoroethylsulfonyl)-5-(2-thienyl)-1H-i midazole, useful for treating arthritis and related diseases.
    Type: Grant
    Filed: January 5, 1978
    Date of Patent: June 26, 1979
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Saul C. Cherkofsky, Thomas R. Sharpe