Patents by Inventor Saumya Radhakrishnan

Saumya Radhakrishnan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11478444
    Abstract: The present disclosure relates to the field of combination therapy for treatment of hematological malignancy selected from myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The disclosure provides a combination therapy comprising plant based compounds and hypomethylating agent (HMA). Particularly, the disclosure provides a combination of: a) a therapeutically effective amount of a combination comprising sulforaphane, resveratrol and curcumin; and b) a therapeutically effective amount of HMA selected from azacitidine (AZA), decitabine (DEC) and a combination thereof, for treating MDS or AML. Said combination provides an enhanced/synergistic effect in the treatment of MDS or AML along with decreasing or overcoming resistance to HMA (azacitidine or decitabine). Methods for decreasing or overcoming resistance to HMA (azacitidine or decitabine), corresponding use of the above described combination and a kit comprising said combination are also provided.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: October 25, 2022
    Assignee: Brio Ventures
    Inventors: Shireen Vali, Taher Abbasi, Tomas Stopka, Lubomir Minarik, Neeraj Kumar Singh, Shahabuddin Usmani, Saumya Radhakrishnan, Huzaifa Sikora, Robinson Vidva, Kristyna Pimkova
  • Publication number: 20210244703
    Abstract: The present disclosure relates to the field of combination therapy for treatment of hematological malignancy selected from myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The disclosure provides a combination therapy comprising plant based compounds and hypomethylating agent (HMA). Particularly, the disclosure provides a combination of: a) a therapeutically effective amount of a combination comprising sulforaphane, resveratrol and curcumin; and b) a therapeutically effective amount of HMA selected from azacitidine (AZA), decitabine (DEC) and a combination thereof, for treating MDS or AML. Said combination provides an enhanced/synergistic effect in the treatment of MDS or AML along with decreasing or overcoming resistance to HMA (azacitidine or decitabine). Methods for decreasing or overcoming resistance to HMA (azacitidine or decitabine), corresponding use of the above described combination and a kit comprising said combination are also provided.
    Type: Application
    Filed: February 5, 2021
    Publication date: August 12, 2021
    Applicant: Brio Ventures, LLC
    Inventors: Shireen VALI, Taher ABBASI, Tomas STOPKA, Lubomir MINARIK, Neeraj Kumar SINGH, Shahabuddin USMANI, Saumya RADHAKRISHNAN, Huzaifa SIKORA, Robinson VIDVA, Kristyna PIMKOVA
  • Publication number: 20150302167
    Abstract: The present disclosure relates to a system for obtaining a therapeutic solution for treatment of a disease or a disorder. The present disclosure also relates to a method of drug discovery and designing therapeutic solutions for various medical conditions, through the said system, comprising database, digital drug library and a processor.
    Type: Application
    Filed: November 8, 2013
    Publication date: October 22, 2015
    Applicant: CELLWORKS GROUP, INC.
    Inventors: Shireen Vali, Taher Abbasi, Pradeep Fernandes, Swaminathan Rajagopalan, Aftab Alam, Robinson Vidva, Prashant Ramachandran Nair, Shweta Kapoor, Saumya Radhakrishnan, Zeba Sultana, Kadambi Sarangapani Ramanujan, Krishna Kumar Tiwari, Ansu Kumar, Neeraj Kumar Singh, Ashish Kumar Agrawal, Anay Ashok Talawdekar, Shahabuddin Usmani, Ragini Singh
  • Publication number: 20150098993
    Abstract: The present invention describes a composition and a kit, each having a plurality of compounds, for use in the treatment of inflammatory joint diseases and chronic inflammatory connective tissue diseases, such as Rheumatoid Arthritis (RA). The invention also relates to a process of obtaining the composition and a method of treating diseases by administration of the compositions.
    Type: Application
    Filed: July 27, 2012
    Publication date: April 9, 2015
    Inventors: Shireen Vali, Robinson Vidva, Prashant Ramachandran Nair, Pradeep Fernandes, Taher Abbasi, Saumya Radhakrishnan
  • Publication number: 20140127295
    Abstract: The present disclosure describes a composition and a kit having a plurality of compounds for use in the treatment of inflammatory joint diseases and chronic inflammatory connective tissue diseases, such as Rheumatoid Arthritis (RA). The disclosure also relates to a process of obtaining the composition and the method of treating diseases by administration of the compositions.
    Type: Application
    Filed: March 7, 2012
    Publication date: May 8, 2014
    Applicants: Cellworks Group, Inc, Cellworks Research India Private Limited
    Inventors: Shireen Vali, Robinson Vidva, Prashant Ramachandran Nair, Pradeep Fernandes, Taher Abbasi, Saumya Radhakrishnan