Abstract: Methods for promoting bone growth, preventing bone damage, and regulating collagen production, involving the administration of a 14-3-3zeta protein or 14-3-3zeta mRNA, are described.

Abstract: The present disclosure provides a continuous and integrated isolation system for providing shareable Fibre to the x (FTTx) network infrastructure across one or more tenants. The continuous and integrated isolation system identifies one or more available segmentation technologies in each of a plurality of end-to-end service paths. In addition, the continuous and integrated isolation system encapsulates a segmentation metadata of each of the plurality of end-to-end service paths. Further, the continuous and integrated isolation system establishes a chain of isolation and continuous end-to-end service path corresponding to each of the plurality of tenant services. Furthermore, the continuous and integrated isolation system enables interconnection of each of the one or more disparate technology implementations for seamless transition. Moreover, the continuous and integrated isolation system includes a segmentation capability engine unit, a segmentation meta-data unit and an isolation control function unit.

Abstract: A system and a method of dynamic bandwidth allocation in the passive optical network comprising a SDN controller (112) to switch a first subscriber of the subscriber group (102) from a first passive optical network (PON) port to a second PON port at the OLT (116) when a first bandwidth availability at the first PON port is less than a predefined bandwidth and a second bandwidth availability at the second PON port is more than the predefined bandwidth. In particular, the predefined bandwidth is a required bandwidth by the first subscriber.

Abstract: The present disclosure relates to an optical line terminal device. The optical line terminal device includes a data center point of presence module, one or more access point of presence modules and one or more aggregation point of presence modules. The data center point of presence module includes a first region and a second region. The first region includes a leaf and spine fabric and a top-of-rack architecture. The second region includes compute infrastructure and storage infrastructure. Further, the one or more access point of presence modules include optical line terminal-Gigabit Passive Optical Networks access input/output and Metro Ethernet Access input/output. The one or more aggregation point of presence include access input/output hardware abstraction, limited compute infrastructure and multi-protocol label switching transfer router.

Abstract: The present disclosure relates to an optical line terminal device. The optical line terminal device includes a data center point of presence module, one or more access point of presence module and one or more aggregation point of presence module. The data center point of presence module includes a first region and a second region. The first region includes a leaf and spine fabric and a top-of-rack architecture. The second region includes compute infrastructure and storage infrastructure. Further, the one or more access point of presence module includes optical line terminal-Gigabit Passive Optical Networks access input/output and Metro Ethernet Access input/output. The one or more aggregation point of presence module includes access input/output hardware abstraction, limited compute infrastructure and multi-protocol label switching transfer router.

Abstract: A method and system for rule based Internet Protocol version 4 (IPv4) to Internet Protocol version 6 (IPv6) migration assisting framework is disclosed. The method provides guidance and assistance for migrating a product, a system or the like to IPv6. The method views across the complete development life cycle, not restricting only to the impacted code base of the system artifacts. The method scans the system artifacts for IPv4 dependency detection and then provides IPv4 Dependency Removal Effort Estimation (IDRE). The IPv4 dependency detection is based on predefined Meta-rules constructed with respect to the context of product. The IDRE combines Analysis Effort (AE) and Project Execution Effort (PEE) to provide a user and/or the organization order of magnitude estimate based on the assessment of IPv4 dependencies, level of coupling with IPv4 dependencies against different parts of the system artifacts.

Abstract: A method and system for rule based Internet Protocol version 4 (IPv4) to Internet Protocol version 6 (IPv6) migration assisting framework is disclosed. The method provides guidance and assistance for migrating a product, a system or the like to IPv6. The method views across the complete development life cycle, not restricting only to the impacted code base of the system artifacts. The method scans the system artifacts for IPv4 dependency detection and then provides IPv4 Dependency Removal Effort Estimation (IDRE). The IPv4 dependency detection is based on predefined Meta-rules constructed with respect to the context of product. The IDRE combines Analysis Effort (AE) and Project Execution Effort (PEE) to provide a user and/or the organization order of magnitude estimate based on the assessment of IPv4 dependencies, level of coupling with IPv4 dependencies against different parts of the system artifacts.

Abstract: The embodiments herein relate to software defined networking (SDN) and, more particularly, to a system and method to construct an engineering environment for API enablement in Software defined networking. The system enables the device use SDN functionality by designing an API model specific to that device. In order to design the device specific API model, an API enablement system initially leverages functionality/capabilities of the device. Further, by analyzing the leveraged device capabilities, the system designs the API model for the device. After implementing the API model on the device, the system performs a review function to ensure that the designed API model is in compliance with set rules and policies. The API model may be refined based on results of the review function.

Abstract: Managing communication services for enabling a distributed user presence and maintaining context specific configuration across the distributed presence. This invention relates to enabling use of communication devices and more particularly to enabling use of multiple applications across multiple communication devices by a user. Embodiments disclosed herein enable coordination between multiple devices and applications of a user, and thus obtain a reliable, accurate control of the various context specific configuration parameters such as user availability, call direction and barring profiles, notifications, media in use, dynamic capabilities of devices and applications, schedule and so on, while providing the user with a seamless experience across the devices and applications. Embodiments disclosed herein enable future device specific systems to efficiently manage the varying communication forms and modes.

Abstract: Managing communication services for enabling a distributed user presence and maintaining context specific configuration across the distributed presence. This invention relates to enabling use of communication devices and more particularly to enabling use of multiple applications across multiple communication devices by a user. Embodiments disclosed herein enable coordination between multiple devices and applications of a user, and thus obtain a reliable, accurate control of the various context specific configuration parameters such as user availability, call direction and barring profiles, notifications, media in use, dynamic capabilities of devices and applications, schedule and so on, while providing the user with a seamless experience across the devices and applications. Embodiments disclosed herein enable future device specific systems to efficiently manage the varying communication forms and modes.

Abstract: The embodiments herein relate to software defined networking (SDN) and, more particularly, to a system and method to construct an engineering environment for API enablement in Software defined networking. The system enables the device use SDN functionality by designing an API model specific to that device. In order to design the device specific API model, an API enablement system initially leverages functionality/capabilities of the device. Further, by analyzing the leveraged device capabilities, the system designs the API model for the device. After implementing the API model on the device, the system performs a review function to ensure that the designed API model is in compliance with set rules and policies. The API model may be refined based on results of the review function.

Abstract: The embodiments provides a method for network-context based content positioning. The method includes receiving a plurality of parameters associated with content, and computing a content positioning relevance index for one or more node using the plurality of parameters. Further, the method includes positioning the content in the network based on the content positioning relevance index.