Abstract: The invention relates to a composition containing catechins found in green tea, to pharmaceutical compositions and medical devices comprising the composition and to the use of these compositions and medical devices in the treatment of coronavirus infections, especially infection with SARS-CoV-2.

Abstract: Tissue splitting biopsy devices and methods use a needle portion and a sheath portion that are configured such as to allow simultaneous sectioning of a tissue to produce two tissue samples with corresponding surfaces using motion of the needle portion relative to the sheath portion. Most preferably, the needle portion has a chisel blade tip and at least two cavities opposite to each other and at the same distance from the tip, while the sheath portion has a sharpened front edge.

Abstract: Tissue splitting biopsy devices and methods use a needle portion and a sheath portion that are configured such as to allow simultaneous sectioning of a tissue to produce two tissue samples with corresponding surfaces using motion of the needle portion relative to the sheath portion. Most preferably, the needle portion has a chisel blade tip and at least two cavities opposite to each other and at the same distance from the tip, while the sheath portion has a sharpened front edge.

Abstract: The formulation and modality of use of a pharmaceutical preparation having the properties described below is described. This preparation is a product comprising a mixture of catechins or polyphenols extracted from chinese green tea or other vegetables that has proven to be efficacious in the chemical prevention of prostate cancer in a clinical pilot study when administered in adequate systemic dosage without the aid of other conventional drugs or remedies and without adverse effects in a group of subjects at risk of development of the illness. The same reduction of the preparation proved efficacious in symptomatology of benign prostate hypertrophy and especially as concerns the difficulty of urination when administered in adequate dosage systemically without the aid of other drugs or conventional remedies and without adverse effects in the patients subject of the study.

Abstract: Methods and compositions are presented in which catechin-containing compositions have statistically significant and strong therapeutic effect in the treatment of LUTS wherein such compositions are stage-specifically administered to a patient diagnosed with HG-PIN and optional coexistent BPH.

Abstract: Tissue splitting biopsy devices and methods use a needle portion and a sheath portion that are configured such as to allow simultaneous sectioning of a tissue to produce two tissue samples with corresponding surfaces using motion of the needle portion relative to the sheath portion. Most preferably, the needle portion has a chisel blade tip and at least two cavities opposite to each other and at the same distance from the tip, while the sheath portion has a sharpened front edge.

Abstract: Methods and compositions are presented in which catechin-containing compositions have statistically significant and strong therapeutic effect in the treatment of LUTS wherein such compositions are stage-specifically administered to a patient diagnosed with HG-PIN and optional coexistent BPH.

Abstract: The formulation and modality of use of a pharmaceutical preparation having the properties described below is described. This preparation is a product comprising a mixture of catechins or polyphenols extracted from chinese green tea or other vegetables that has proven to be efficacious in the chemical prevention of prostate cancer in a clinical pilot study when administered in adequate systemic dosage without the aid of other conventional drugs or remedies and without adverse effects in a group of subjects at risk of development of the illness. The same reduction of the preparation proved efficacious in symptomatology of benign prostate hypertrophy and especially as concerns the difficulty of urination when administered in adequate dosage systemically without the aid of other drugs or conventional remedies and without adverse effects in the patients subject of the study.

Abstract: A method used to design a microchip (DNA microarray) for identifying the presence of prostate tumor, evaluating its degree of mali-gnity (typization, characterization) and supplying information allowing prediction of the clinical course of the illness (prognosis) is discussed below. The method is based on assessment of the levels of expression of a definite package of genes in the tumoral tissue in comparison with the corresponding benign tissue. The readings thus obtained, - alone, in different combinations with each other or in different combinations and integrated with standardized clinical data - give the results described above.