Patents by Inventor Savitri Mandapati

Savitri Mandapati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADENO-ASSOCIATED VIRUS (AAV) SYSTEMS FOR TREATMENT OF PROGRANULIN ASSOCIATED NEURODEGENERATIVE DISEASES OR DISORDERS
    Publication number: 20240318199
    Abstract: The disclosure provides, in part, optimally-modified progranulin (PGRN) cDNA and associated genetic elements for use in recombinant adeno-associated virus (rAAV)-based gene therapy for neurodegenerative disorders characterized by cognitive disruption, behavioral impairment, and deficient lysosomal storage, including familial frontotemporal dementia (FTD), frontotemporal lobar degeneration (FTLD), neuronal ceroid lipofuscinosis (NCL), or Alzheimer's disease (AD).
    Type: Application
    Filed: September 26, 2023
    Publication date: September 26, 2024
    Inventors: Juan Li, Tanaz Farivar, Savitri Mandapati, Steven Pennock, Mark Shearman, Judith Newmark, Adrian M. Timmers