Patents by Inventor Sawako Takeshita

Sawako Takeshita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating neuropathic pain
    Patent number: 8754036
    Abstract: An object of the present invention is to provide a substance which is able to be an active ingredient for the improvement of dysfunction caused by nerve damage. An improving agent for dysfunction due to nerve damage of the present invention as a means for resolution thereof is characterized in that it comprises an endo-?-N-acetylglucosaminidase type enzyme which hydrolyzes an N-acetylglucosamide bond in a keratan sulfate backbone as an active ingredient. When the improving agent of the present invention is administered, clinical improvement is achieved in motor neuron dysfunction and sensory neuron dysfunction such as neuropathic pain represented by a pain caused by allodynia and hyperalgesic reaction of the object to be treated.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: June 17, 2014
    Assignees: National University Corporation Nagoya University, Seikagaku Corporation
    Inventors: Kenji Kadomatsu, Yukihiro Matsuyama, Akiomi Tanaka, Sawako Takeshita
  • IMPROVING AGENT FOR DYSFUNCTION DUE TO NEUROPATHY AND RHO KINASE ACTIVATION INHIBITOR
    Publication number: 20110059508
    Abstract: An object of the present invention is to provide a substance which is able to be an active ingredient for the improvement of dysfunction caused by nerve damage. An improving agent for dysfunction due to nerve damage of the present invention as a means for resolution thereof is characterized in that it comprises an endo-?-N-acetylglucosaminidase type enzyme which hydrolyzes an N-acetylglucosamide bond in a keratan sulfate backbone as an active ingredient. When the improving agent of the present invention is administered, clinical improvement is achieved in motor neuron dysfunction and sensory neuron dysfunction such as neuropathic pain represented by a pain caused by allodynia and hyperalgesic reaction of the object to be treated.
    Type: Application
    Filed: June 30, 2008
    Publication date: March 10, 2011
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, SEIKAGAKU CORPORATION
    Inventors: Kenji Kadomatsu, Yukihiro Matsuyama, Akiomi Tanaka, Sawako Takeshita
  • Mutants of core 2 B-1, 6-N-acetylglycosaminyltransferase
    Publication number: 20050142574
    Abstract: This invention provides novel mutant Core 2 GlcNAcT nucleic acids, polypeptides encoded by the nucleic acids, and uses of the nucleic acids and polypeptides
    Type: Application
    Filed: June 10, 2004
    Publication date: June 30, 2005
    Inventors: Steve Bryson, Dale Cumming, Alessandro Datti, James Rini, Sawako Takeshita, Roderick Tse, April Lew
  • Quantitative determination method for heparan sulfate and diagnostic method using the same
    Patent number: 6150115
    Abstract: The present invention relates to a quantitative determination method for heparan sulfate in body fluid specimens of various chronic diseases, in urine samples of diabetic nephropathy and for diagnosing hepatic diseases and rheumatoid arthritis in blood specimens. And also this method provides a diagnostic tool for judging the condition of diabetic nephropathy, hepatic diseases and rheumatoid arthritis by determination of changes by use of aforementioned quantitative determination of heparan sulfate.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: November 21, 2000
    Assignee: Seikagaku Kogyo Kabushiki Kaisha
    Inventors: Shuichi Miyaura, Sawako Takeshita, Takeshi Ishimaru