Abstract: A biochip production apparatus, which forms an array of biopolymers on a substrate, has a substrate moving unit which moves the substrate up, down, left and right, and a plurality of solution supply units which are disposed to be fixed, in which solutions containing biopolymers are stored, which deposit the solutions on the substrate. When the solution supply units deposit the solutions on a predetermined position of the substrate, the substrate moving unit moves the substrate to a predetermined position.

Abstract: There is provided a biochip capable of quantitatively grasping hybridization efficiency. In the biochip comprising a plurality of probe sites with target molecules bonded thereto, respectively, the probe sites disposed thereon, the marker sites with a known number of fluorescent molecules bonded thereto, respectively, are disposed. With the biochip, the number of the fluorescent molecules bonded to the respective marker sites is already known, so that respective hybridization efficiencies at the probe sites can be quantitatively grasped by comparing respective intensity of fluorescent light of the probe sites with a intensity of fluorescent light of the marker sites. The fluorescent molecule may be bonded to the respective marker sites when the biochip is formed, or the respective marker sites may be made up such that the fluorescent molecule of a predetermined molecular weight is bonded thereto by a predetermined processing applied to the biochip.

Abstract: The cartridge for chemical reaction according to the invention is a cartridge for chemical reaction that causes chemical reaction by feeding an internal liquid by way of deformation caused by external forces. The entirety of a target molecule detecting chip is housed in the cartridge for chemical reaction. According to the cartridge for chemical reaction, the entire target molecule detecting chip is housed in the cartridge for chemical reaction so that it supports various forms of target molecule detecting chips. The target molecule detecting chip may be a penetration type chip that allows a solution including target molecules to penetrate the target molecule detecting chip. In this case, the solution may pass inside the penetration type chip by way of deformation of the cartridge for chemical reaction caused by external forces applied to the cartridge for chemical reaction.

Abstract: The present invention provides a dendrimer-based biochip, wherein a flow channel through which a solution containing biopolymer molecules is flowed is formed in the substrate of the biochip, a plurality of dendrimer molecules one end of each of which is bound to the walls of the flow channel are formed thereon, and probe biopolymer or antibody molecules are bound to the tips of the dendrimer molecules so that, if the probe biopolymer molecules are bound, then target biopolymer molecules can be captured by means of a complementary combination and, if the antibody molecules are bound, then protein can be extracted by means of antigen-antibody reaction, whereby biopolymers can be retrieved in a highly efficient manner.

Abstract: Detector calibration methods are described which enable the measurement of absolute power. The method includes using a power meter with traceability to the national standard for optical power to calibrate the power of each photodetector device of a detector with photodetector device arrays arranged in one dimension or two dimensions and to calibrate the output signals of the detector making it possible to measure the spatial distribution of a light source's power and also values of optical power with traceability to the national standard directly from the output signals of the detector.

Abstract: A biochip production apparatus for arranging a plurality of different biopolymers on a substrate of a biochip, has a support body which enables to move in any directions, a stamp to be attached to the support body, and a biopolymer solution supply unit which supplies plural kinds of biopolymer solutions to be fixed on a surface of the stamp. The biopolymer solution supply unit fixes the biopolymer solutions on the surface of the stamp, and the stamp to which the biopolymer solutions is fixed is pressed against the surface of the substrate to thereby fix the biopolymer solutions on the surface of the biochip substrate in the same arrangement as in the stamp to form a plurality of sites simultaneously.

Abstract: The present invention relates to a method of extracting nucleic acid or protein, in which multi-layer dendorimers are formed on the surface of fine particles, amino radicals for capturing nucleic acid or protein are formed on the surface of these dendorimers, and nucleic acid or protein is extracted using these amino radicals. The present invention can greatly and easily increase the recovery ratio of nucleic acid or protein.

Abstract: The present invention provides a dendrimer-based biochip, wherein a flow channel through which a solution containing biopolymer molecules is flowed is formed in the substrate of the biochip, a plurality of dendrimer molecules one end of each of which is bound to the walls of the flow channel are formed thereon, and probe biopolymer or antibody molecules are bound to the tips of the dendrimer molecules so that, if the probe biopolymer molecules are bound, then target biopolymer molecules can be captured by means of a complementary combination and, if the antibody molecules are bound, then protein can be extracted by means of antigen-antibody reaction, whereby biopolymers can be retrieved in a highly efficient manner.

Abstract: The present invention makes it possible to realize a chemical reaction cartridge, which enables prescribed protocols to be achieved easily without differences among operators, which is sealed and disposable, and which has a safe structure against viruses or dangerous drugs.

Abstract: The present invention relates to a detector calibration method which enables the measurement of absolute power, uses a power meter with traceability to the national standard for optical power to calibrate the power of each photodetector device of a detector with photodetector device arrays arranged in one dimension or two dimensions and to calibrate the output signals of the detector, and makes it possible to measure the spatial distribution of a light source's power and also values of optical power with traceability to the national standard directly from the output signals of the detector.