Abstract: A support body includes a concentrating portion, which concentrates an object, between a first end portion and a second end portion. When an area of a cut section of a flow path when cut at a predetermined position in a first direction along a plane orthogonal to the first direction is a flow path cross-sectional area, a flow path cross-sectional area of the concentrating portion is smaller than a flow path cross-sectional area in a first region closer to a first end portion side than the concentrating portion, and a flow path cross-sectional area of a second region closer to the second end portion side than the concentrating portion is larger than the flow path cross-sectional area of the concentrating portion.

Abstract: A cell analysis method includes a mixing step of mixing a cell as an analyte, a metal ion solution, and a reducing agent to prepare a mixture solution, a metal microstructure generation step of reducing metal ions in the mixture solution by reducing action of the reducing agent to generate a metal microstructure on a support, and attaching the cell or a cell-derived substance to the metal microstructure, a drying step of, after the metal microstructure generation step, drying the support, a measurement step of, after the drying step, irradiating the metal microstructure on the support with excitation light, and measuring a spectrum of Raman scattered light generated by the excitation light irradiation, and an analysis step of analyzing the cell based on the spectrum of the Raman scattered light.

Abstract: A method for selecting cells highly responsive to a target substance according to the present invention comprises step of: (1a) bringing a sample containing a target substance into contact with a plurality of cells, wherein the cells are cells having a receptor for the target substance and a fluorescent indicator, and the fluorescent indicator emits fluorescence as a result of binding between the target substance and the receptor; (1b) calculating a fluorescence intensity increase rate for each of the cells; and (1c) selecting arbitrary cells exhibiting a fluorescence intensity increase rate within the top 50% among the plurality of cells. According to the present invention, it is possible to detect the target substance in the sample with high sensitivity.

Abstract: A cell adhesion composition according to one aspect of the present invention comprises: an amphiphilic compound; and a conjugate of a DNA and a hydrophilic molecule, wherein the amphiphilic compound has a hydrophobic group that can non-covalently bond to a cell membrane, and a hydrophilic group, and wherein a weight-average molecular weight of the hydrophilic molecule of the conjugate is larger than a weight-average molecular weight of a hydrophilic molecule from which the hydrophilic group of the amphiphilic compound derives. According to such a cell adhesion composition, it is possible to impart a cell adhesion ability to a base material at an arbitrary timing by using light having an arbitrary wavelength.

Abstract: The support body includes a concentrating portion, which concentrates the object, between the first end portion and the second end portion. When an area of a cut section of the flow path when cut at a predetermined position in the first direction along a plane orthogonal to the first direction is a flow path cross-sectional area, a flow path cross-sectional area of the concentrating portion is smaller than a flow path cross-sectional area in a first region closer to a first end portion side than the concentrating portion, and a flow path cross-sectional area of a second region closer to the second end portion side than the concentrating portion is larger than the flow path cross-sectional area of the concentrating portion.