Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody or fusion protein thereof. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody fusion protein thereof.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.

Abstract: This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-factor D antibody. Specifically, the invention relates to methods of treating an AP-mediated disease or AP-mediated disorder in an individual by contacting the individual with an anti-factor D antibody.

Abstract: This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-factor D antibody. Specifically, the invention relates to methods of treating an AP-mediated disease or AP-mediated disorder in an individual by contacting the individual with an anti-factor D antibody.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody or fusion protein thereof. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody fusion protein thereof.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.

Abstract: This invention relates to inhibition of the complement signaling using an anti-C5a antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5a antibody.

Abstract: This invention relates to selective inhibition of the alternative pathway (AP) of the complement system using an anti-factor D antibody. Specifically, the invention relates to methods of treating an AP-mediated disease or AP-mediated disorder in an individual by contacting the individual with an anti-factor D antibody.

Abstract: In a rising gathered member 4 of an absorbent main body 3 attached to an external sheet 2, an inward folded base end 4b is joined astride a side end 13a of a top sheet 13 as a top surface of the absorbent main body 3 and a side end 14a of a back sheet 14 so that the rising gathered member 4 rises from a most side edge 3a in a width direction of the absorbent main body 3 and, also, the back sheet 14 of the absorbent main body 3 is attached onto a skin-contacting surface side of a crotch part R of a second external sheet 8 at an inward position at a prescribed width W5 from the most side edge 3a of the absorbent main body 3 as an outermost joint position. With the above constitution, it is possible to effectively prevent any lateral leakage of urine and the like, even if a disposable absorbent article is shifted.

Abstract: A bondable innermost edge e? of a hot melt adhesive to be applied to a base end 4a of each of a pair of raisable flaps 4 is disposed outside away from an inner edge 4d of the base end 4a in a state that each raisable flap 4 is folded into a multi-layered manner in bonding the base ends 4a of the raisable flaps 4 to an outer sheet at the opposite sides of an absorbent member 3 with the hot melt adhesive. This arrangement eliminates the likelihood that a free end 4b of each raisable flap 4 may be adhered to the base end 4a by an excessively and extensively applied adhesive portion even if the adhesive is excessively and extensively applied.

Abstract: A bondable innermost edge e? of a hot melt adhesive to be applied to a base end 4a of each of a pair of raisable flaps 4 is disposed outside away from an inner edge 4d of the base end 4a in a state that each raisable flap 4 is folded into a multi-layered manner in bonding the base ends 4a of the raisable flaps 4 to an outer sheet at the opposite sides of an absorbent member 3 with the hot melt adhesive. This arrangement eliminates likelihood that a free end 4b of each raisable flap 4 may be adhered to the base end 4a by an excessively and extensively applied adhesive portion even if the adhesive is excessively and extensively applied.