Patents by Inventor Sayed Elmarakby

Sayed Elmarakby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS CONTAINING O-SULFATE AND O-PHOSPHATE CONTAINING ARYL SULFONAMIDE DERIVATIVES USEFUL AS beta-AMYLOID INHIBITORS
    Publication number: 20090181932
    Abstract: A synthetic compound characterized by having the structure of formula I or II or a pharmaceutically acceptable salt and/or hydrate thereof is provided. Formula I and formula II are defined as follows. wherein R1 is substituted aryl or substituted heteroaryl; R2 and R3 are independently selected from the group consisting of CF3, substituted phenyl, C1-C4 alkyl, substituted C1-C4 alkyl, (CF3)nC1-C4alkyl, (CF3)n(substituted C1-C4 alkyl), provided that when R2 or R3 is CF3, the other is not an unsubstituted alkyl; R4 and R4? are independently selected from the group consisting of M, C1-C4 alkyl, phenyl, and benzyl, wherein M is a metal ion is selected from the group consisting of sodium, lithium, calcium, magnesium and potassium, or R4 and R4? are taken together to form a cyclic structure. Methods of making such compounds and uses thereof are also provided.
    Type: Application
    Filed: January 7, 2009
    Publication date: July 16, 2009
    Applicant: Wyeth
    Inventors: David Zenan LI, Dane Springer, Sayed Elmarakby, Appavu Chandrasekaran, Anthony F. Kreft, III
  • PRODRUG SUBSTITUTED BENZOXAZOLES AS ESTROGENIC AGENTS
    Publication number: 20080255057
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein Q, Q2, R1, R2, R2a, R3, R3a, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 28, 2008
    Publication date: October 16, 2008
    Applicant: WYETH
    Inventors: Sayed Elmarakby, Ping Cai, Appavu Chandrasekaran, Mark Ruppen, Rasmy Talaat
  • Prodrug substituted benzoxazoles as estrogenic agents
    Publication number: 20060046968
    Abstract: This invention provides estrogen receptor modulators of formula I, having the structure wherein Q, Q2, R1, R2, R2a, R3, R3a, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 24, 2005
    Publication date: March 2, 2006
    Applicant: Wyeth
    Inventors: Sayed Elmarakby, Ping Cai, Appavu Chandrasekaran, Mark Ruppen, Rasmy Talaat