Patents by Inventor Sayumi Yamazoe

Sayumi Yamazoe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES MODIFIED FOR TRANSGLUTAMINASE CONJUGATION, CONJUGATES THEREOF, AND METHODS AND USES
    Publication number: 20220031860
    Abstract: Antibodies are modified by replacing amino acids in the heavy chain CH1, CH2, or CH3 or light chain constant region with selected replacement glutamine-containing sequences to render them amenable to conjugation by the enzyme transglutaminase.
    Type: Application
    Filed: December 10, 2019
    Publication date: February 3, 2022
    Inventors: Pavel STROP, Chetana RAO-NAIK, Xiaodi DENG, Paul O. SHEPPARD, Sean Matthew WEST, Jason Michael HOGAN, Sayumi YAMAZOE
  • ANTIBODY COMPRISING A GLUTAMINE-CONTAINING LIGHT CHAIN C-TERMINAL EXTENSION, CONJUGATES THEREOF, AND METHODS AND USES
    Publication number: 20220016260
    Abstract: An antibody has a glutamine-containing extension at the C-terminus of a light chain thereof, making it suitable for conjugation via transglutaminase-mediated transamidation.
    Type: Application
    Filed: November 25, 2019
    Publication date: January 20, 2022
    Inventors: Pavel STROP, Chetana RAO-NAIK, Xiaodi DENG, Paul O. SHEPPARD, Patrick G. HOLDER, Sayumi YAMAZOE
  • Cell adhesion promoting agent and method of promoting cell adhesion
    Patent number: 8685976
    Abstract: The subject invention discloses an agent for promoting cell adhesion to a support, comprising a dispirotripiperazine derivative represented by Formula I below or a salt thereof; a method for promoting cell adhesion to a support comprising adding the dispirotripiperazine derivative represented by Formula I below or a salt thereof to a culture medium, or applying the same to a support; and an agonist of a heparin sulfate that comprises the dispirotripiperazine derivative represented by Formula I below or a salt thereof, and that promotes cell adhesion and/or cell growth.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: April 1, 2014
    Assignee: Kyoto University
    Inventors: Motonari Uesugi, Sayumi Yamazoe
  • CYCLIZING LINKER AND CYCLIC CAGED MORPHOLINOS
    Publication number: 20130066059
    Abstract: A bifunctional and photocleavable linker for cyclizing a morpholino-based oligonucleotide, having the formula: with the Linker as a photoactive group derivatized spacer molecule that presents two functional groups for cyclizing a selected morpholino and with the R group as a photoactive group utilized in the process of photocleavage and the X and Z groups are functional groups utilized for attachment to a morpholino to generate a cyclic structure.
    Type: Application
    Filed: August 23, 2012
    Publication date: March 14, 2013
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: JAMES K. CHEN, ILYA A. SHESTOPALOV, SAYUMI YAMAZOE
  • CELL ADHESION PROMOTING AGENT AND METHOD OF PROMOTING CELL ADHESION
    Publication number: 20110117651
    Abstract: The subject invention discloses an agent for promoting cell adhesion to a support, comprising a dispirotripiperazine derivative represented by Formula I below or a salt thereof; a method for promoting cell adhesion to a support comprising adding the dispirotripiperazine derivative represented by Formula I below or a salt thereof to a culture medium, or applying the same to a support; and an agonist of a heparin sulfate that comprises the dispirotripiperazine derivative represented by Formula I below or a salt thereof, and that promotes cell adhesion and/or cell growth.
    Type: Application
    Filed: June 16, 2009
    Publication date: May 19, 2011
    Inventors: Motonari Uesugi, Sayumi Yamazoe