Patents by Inventor Scheffer C. G. Tseng
Scheffer C. G. Tseng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8455015Abstract: Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.Type: GrantFiled: April 30, 2010Date of Patent: June 4, 2013Assignee: Tissuetech, Inc.Inventors: Ying-Ying Gao, Scheffer C. G. Tseng
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Patent number: 8440240Abstract: The present invention relates to a method for treating a disorder chosen from ocular Demodex, Demodex-induced blepharitis, rosacea, acne, and meibomian gland dysfunction in a patient in need thereof, comprising administering to the patient a composition comprising a therapeutically effective amount of a substance chosen from at least one of an isoprenoidal essential oil such as Tea Tree Oil; Terpinen-4-ol; Carvone; alpha-Terpineol; Cardinene; d-Carvone; l-Carvone; gamma-Terpinene; alpha-Terpinene; 1,8-Cineole; alpha-Terpineol; para-Cimene; alpha-Pinene; Limonene; (R)-(+)-Limonene; alpha-Thugene; Eucalyptol; (+)-Ledene; Cuminic Aldehyde; and Myrcene; the administration comprising contacting or scrubbing an affected area of skin or hair, or eyelid margin and lashes of the patient with the composition; also disclosed are a method for treating mange and mite infestations on a mammalian animal; and kits for in-office and at home treatments of the disorders.Type: GrantFiled: July 13, 2011Date of Patent: May 14, 2013Assignee: TissueTech, Inc.Inventors: Ying-Ying Gao, Scheffer C. G. Tseng
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Patent number: 8128968Abstract: Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.Type: GrantFiled: August 29, 2007Date of Patent: March 6, 2012Assignee: Tissuetech, Inc.Inventors: Ying-Ying Gao, Scheffer C. G. Tseng
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Publication number: 20120004320Abstract: The present invention relates to a method for treating a disorder chosen from ocular Demodex, Demodex-induced blepharitis, rosacea, acne, and meibomian gland dysfunction in a patient in need thereof, comprising administering to the patient a composition comprising a therapeutically effective amount of a substance chosen from at least one of an isoprenoidal essential oil such as Tea Tree Oil; Terpinen-4-ol; Carvone; alpha-Terpineol; Cardinene; d-Carvone; l-Carvone; gamma-Terpinene; alpha-Terpinene; 1,8-Cineole; alpha-Terpineol; para-Cimene; alpha-Pinene; Limonene; (R)-(+)-Limonene; alpha-Thugene; Eucalyptol; (+)-Ledene; Cuminic Aldehyde; and Myrcene; the administration comprising contacting or scrubbing an affected area of skin or hair, or eyelid margin and lashes of the patient with the composition; also disclosed are a method for treating mange and mite infestations on a mammalian animal; and kits for in-office and at home treatments of the disorders.Type: ApplicationFiled: July 13, 2011Publication date: January 5, 2012Applicant: TissueTech,Inc.Inventors: Ying-Ying Gao, Scheffer C.G. Tseng
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Patent number: 7824671Abstract: The present invention relates to a composition for implantation in the subretinal space of an eye, the composition including amniotic membrane, which may be cryopreserved human amniotic membrane, and a plurality of retinal pigment epithelial (RPE) cells or RPE equivalent cells present at the amniotic membrane. The amniotic membrane may be intact, epithelially denuded, or otherwise treated. The invention includes the use of amniotic membrane for the culturing of RPE cells thereon, forming a surgical graft for replacement of Bruch's membrane as a substrate, and for the transplanting of RPE cells to the subretinal space. The composition does not elicit immunological reactions to alloantigens or to RPE specific autoantigens; and exerts anti-inflammatory, and angiogentic, and anti-scarring effects. The invention includes methods and kits for making or using composites including amniotic membrane and RPE cells. Also disclosed is a device for harvesting RPE cells.Type: GrantFiled: October 6, 2003Date of Patent: November 2, 2010Assignee: Tissuetech, Inc.Inventors: Susanne Binder, Scheffer C. G. Tseng
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Publication number: 20100273870Abstract: Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.Type: ApplicationFiled: April 30, 2010Publication date: October 28, 2010Applicant: TISSUETECH, INC.Inventors: Ying-Ying Gao, Scheffer C.G. Tseng
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Publication number: 20090214676Abstract: The present invention relates to a method for treating a disorder chosen from ocular Demodex, Demodex-induced blepharitis, rosacea, acne, and meibomian gland dysfunction in a patient in need thereof, comprising administering to the patient a composition comprising a therapeutically effective amount of a substance chosen from at least one of an isoprenoidal essential oil such as Tea Tree Oil; Terpinen-4-ol; (+)-Carvone; alpha-Terpineol; Cardinene; d-Carvone; l-Carvone; gamma-Terpinene; alpha-Terpinene; 1,8-Cineole; alpha-Terpineol; para-Cimene; alpha-Pinene; Limonene; (R)-(+)-Limonene; alpha-Thugene; Eucalyptol; (+)-Ledene; Cuminic Aldehyde; and Myrcene; the administration comprising contacting or scrubbing an affected area of skin or hair, or eyelid margin and lashes of the patient with the composition; also disclosed are a method for treating mange and mite infestations on a mammalian animal; and kits for in-office and at home treatments of the disorders.Type: ApplicationFiled: April 28, 2006Publication date: August 27, 2009Applicant: TissueTech, Inc.Inventors: Ying-Ying Gao, Scheffer C.G. Tseng
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Publication number: 20090061025Abstract: Compositions containing about 0.6% to about 20% of tea tree oil are described. Some compositions are in the form of solutions, suspensions, spray, lotions, gels, pastes, medicated sticks, balms, cleansers (including shampoos and soaps), creams, or ointments. Also described are compositions and methods for use in treating ocular Demodex infestations and related conditions using such compositions.Type: ApplicationFiled: August 29, 2007Publication date: March 5, 2009Applicant: TISSUETECH, INC.Inventors: Ying-Ying GAO, Scheffer C.G. TSENG
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Patent number: 7494802Abstract: The present invention relates to a biopolymer covering for a tissue surface including, for example, a dressing, a bandage, a drape such as a bandage contact lens, a composition or covering to protect tissue, a covering to prevent adhesions, to exclude bacteria, to inhibit bacterial activity, or to promote healing or growth of tissue. An example of such a composition is an amniotic membrane covering for an ocular surface. Use of a covering for a tissue surface according to the invention eliminates the need for suturing. The invention also includes devices facilitating the fastening of a membrane to a support, culture inserts, compositions, methods, and kits for making and using coverings for a tissue surface and culture inserts. Compositions according to the invention may include cells grown on a membrane or attached to a membrane, and such compositions may be used as scaffolds for tissue engineering or tissue grafts.Type: GrantFiled: March 14, 2003Date of Patent: February 24, 2009Assignee: TissueTech, Inc.Inventors: Scheffer C. G. Tseng, Helga Sandoval, William G. Lee
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Patent number: 7121666Abstract: An apparatus and method for the kinetic analysis of tear interference is disclosed. The apparatus includes a light source for illuminating a tear film of a cornea, an optical train for modifying the light before it reaches the cornea and after it is the carrier of an image from the cornea, an image recorder to record a series of images of the illuminated tear film, and an image output for providing the series of images to a display; the series of images illustrating a tear film dispersion pattern indicative of a tear stability condition. The method includes the steps of illuminating the film on a cornea of said eye with light, recording a series of images of the illuminated film, and outputting the series of images to a display. The series of images illustrating at least one of a lipid film spread and a tear film dispersion pattern indicative of a tear stability condition.Type: GrantFiled: April 24, 2002Date of Patent: October 17, 2006Inventors: Scheffer C. G. Tseng, Eiki Goto
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Publication number: 20040181240Abstract: The present invention relates to a biopolymer covering for a tissue surface including, for example, a dressing, a bandage, a drape such as a bandage contact lens, a composition or covering to protect tissue, a covering to prevent adhesions, to exclude bacteria, to inhibit bacterial activity, or to promote healing or growth of tissue. An example of such a composition is an amniotic membrane covering for an ocular surface. Use of a covering for a tissue surface according to the invention eliminates the need for suturing. The invention also includes devices facilitating the fastening of a membrane to a support, culture inserts, compositions, methods, and kits for making and using coverings for a tissue surface and culture inserts. Compositions according to the invention may include cells grown on a membrane or attached to a membrane, and such compositions may be used as scaffolds for tissue engineering or tissue grafts.Type: ApplicationFiled: April 19, 2004Publication date: September 16, 2004Inventors: Scheffer C.G. Tseng, Helga Sandoval, William G. Lee
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Publication number: 20020180929Abstract: An apparatus and method for the kinetic analysis of tear interference is disclosed. The apparatus includes a light source for illuminating a tear film of a cornea, an optical train for modifying the light before it reaches the cornea and after it is the carrier of an image from the cornea, an image recorder to record a series of images of the illuminated tear film, and an image output for providing the series of images to a display; the series of images illustrating a tear film dispersion pattern indicative of a tear stability condition. The method includes the steps of illuminating the film on a cornea of said eye with light, recording a series of images of the illuminated film, and outputting the series of images to a display. The series of images illustrating at least one of a lipid film spread and a tear film dispersion pattern indicative of a tear stability condition.Type: ApplicationFiled: April 24, 2002Publication date: December 5, 2002Inventors: Scheffer C.G. Tseng, Eiki Goto
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Patent number: 6438398Abstract: A method of evaluating clearance of fluorescein dye instilled into tear film having a greater sensitivity and specificity for diagnosing a tear film disorder as the cause of a patient's ocular irritation and ocular surface disease than can be achieved using the traditional methods. The inventive method can be performed using a diagnostic kit for evaluating tear fluorescence clearance in which the concentration of tear fluorescein is visually quantified via a color standard.Type: GrantFiled: March 3, 2000Date of Patent: August 20, 2002Assignee: The University of MiamiInventors: Stephen C. Pflugfelder, Scheffer C. G. Tseng, Adolfo Afonso, Angelo Macri
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Patent number: 6326019Abstract: A method for making, storing and using a surgical graft from human amniotic membrane; the resulting graft; and the storage solution. The amniotic membrane is obtained from human placenta, from which the chorion has been separated. Sheets of the amniotic membrane are cut to size and mounted on filter paper. The cells of the amniotic membrane are killed, preferably while being frozen and thawed in the storage solution. The storage solution comprises a culture medium and a hyperosmotic agent, wherein the hydration of the amniotic membrane is maintained. The membrane can be impregnated with therapeutic agents, prior to storage, for use in post surgical healing or other therapies.Type: GrantFiled: July 25, 2000Date of Patent: December 4, 2001Inventor: Scheffer C. G. Tseng
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Patent number: 6152142Abstract: A method for making, storing and using a surgical graft from human amniotic membrane; the resulting graft; and the storage solution. The amniotic membrane is obtained from human placenta, from which the chorion has been separated. Sheets of the amniotic membrane are cut to size and mounted on filter paper. The cells of the amniotic membrane are killed, preferably while being frozen and thawed in the storage solution. The storage solution comprises a culture medium and a hyperosmotic agent, wherein the hydration of the amniotic membrane is maintained. The membrane can be impregnated with therapeutic agents, prior to storage, for use in post surgical healing or other therapies.Type: GrantFiled: February 20, 1998Date of Patent: November 28, 2000Inventor: Scheffer C. G. Tseng
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Patent number: 6153607Abstract: A preservative-free composition containing an effective amount of a corticosteroid in an aqueous carrier to treat a dry eye condition. The composition may be provided as a part of a therapeutic regimen to treat a variety of dry eye conditions and ocular surface disorders manifesting delayed tear clearance previously not readily treatable. The composition may be packaged as containers of single dosage amounts of the corticosteroid-aqueous composition sufficient for pulsed-therapy of acute exacerbations of the irritation symptoms and ocular surface disease of conditions associated with dry eye and delayed tear clearance.Type: GrantFiled: December 4, 1996Date of Patent: November 28, 2000Assignee: University of MiamiInventors: Stephen C. Pflugfelder, Scheffer C. G. Tseng, Andrew J. W. Huang
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Patent number: 5652209Abstract: The present invention relates to medicinal compositions and more particularly refers to such compositions for tear replacement therapy having products of human lacrimal gland acinar epithelia, and more specifically, growth factors or cytokines, in particular, the transforming growth factor beta (TGF.beta.).Type: GrantFiled: April 29, 1994Date of Patent: July 29, 1997Assignee: University of MiamiInventors: Stephen C. Pflugfelder, Kenichi Yoshino, Scheffer C. G. Tseng, Andrew J. W. Huang