Patents by Inventor Schneur Rachlin

Schneur Rachlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6313174
    Abstract: The compounds of the present invention are represented by general formula (I) in which formula R1 and R2 stand independently for one or more, similar or different substituents selected from the group consisting of hydrogen, halogen, hydroxy, mercapto, trifluoromethyl, amino, alkyl, alkoxy, alkylthio, alkylamino, or alkoxycarbonyl, the C-content of which can be from 1 to 5, cyano, carboxy, carbamoyl, phenyl, or nitro; R3 stands for hydrogen, halogen, hydroxy, mercapto, trifluoromethyl, amino, alkyl, alkoxy, alkylthio, alkylamino, or alkoxycarbonyl, the C-content of which can be from 1 to 5, phenyl, cyano, carboxy, or carbamoyl; R4, R5 and R6 stand independently for hydrogen, trifluoromethyl, alkyl, carbamoyl, alkoxycarbonyl, or alkyloxo, the C-content of which can be from 1 to 5; X stands for oxygen, N—OH, N—O-alkyl, dialkoxy, cyclic dialkoxy, dialkylthio, or cyclic dialkylthio, the C-content of which can be from 1 to 5.
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: November 6, 2001
    Assignee: Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab)
    Inventors: Erik Rytter Ottosen, Schneur Rachlin
  • Patent number: 5945433
    Abstract: The present invention relates to hitherto unknown compounds of formula (I) in which R.sub.1 is hydrogen or halogen, preferably fluorine or chlorine, and m is 0, 1 or 2. The present compounds are of value in the human and veterinary practice as leukotriene antagonists.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: August 31, 1999
    Assignee: Leo Pharmaceutical Products, Ltd. A/S
    Inventors: Dorte Kirstein, Schneur Rachlin
  • Patent number: 5576438
    Abstract: The present invention relates to hitherto unknown compounds of formula; Y stands for --CH.dbd.CH--; R.sub.1 is hydrogen or halogen, preferably fluorine, chlorine or bromine; R.sub.2 is halogen, preferably fluorine, chlorine or bromine, CH.sub.3, OCH.sub.3, NO.sub.2 or CF.sub.3, and n=0-3, preferably 0, 1 or 2; A stands for an acidic group, e.g. carboxy, 1-H-tetrazolyl or a hydroxamic acid group. The present compounds are of value in the human and veterinary practice as lipoxygenase inhibitors and/or leukotriene antagonists.
    Type: Grant
    Filed: January 13, 1995
    Date of Patent: November 19, 1996
    Assignee: Leo Pharmaceutical Products Ltd. A/S (L.o slashed.vens Kemiske Fabrik Produktionsaktiesel Skab)
    Inventors: Dorte Kirstein, Schneur Rachlin
  • Patent number: 5234932
    Abstract: The present invention relates to hitherto unknown compounds of formula, in which m and n stand for an integer from 0-5, p stands for 0 or 1, and q stands for an integer from 0-4, R.sub.1 and R.sub.2 are the same or different and stand for hydrogen, halogen, nitro, amino, alkyl or alkoxy; R.sub.3 is hydroxy, hydrogen, straight or branched, saturated or unsaturated C.sub.1 -C.sub.6 alkyl; R.sub.5 stands for an acidic group, e.g. carboxy, 1-H tetrazolyl, a sulphonic acid group, a sulfamyl group, a sulphinic acid group, or a hydroxamic acid group; R.sub.4 and R.sub.6 are the same or different and stand for hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C.sub.1 -C.sub.6 alkyl groups or unsubstituted or substituted aralkyl groups. R.sub.7 has the same meaning as R.sub.5 or represents a hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C.sub.1 -C.sub.6 -alkyl group.
    Type: Grant
    Filed: January 29, 1992
    Date of Patent: August 10, 1993
    Assignee: Leo Pharmaceutical Products ltd.
    Inventors: Schneur Rachlin, Erik T. Hansen
  • Patent number: 5110819
    Abstract: The present invention relates to hitherto unknown compounds of formula, in which formula R.sub.1 stands for hydrogen, straight or branched, saturated or unsaturated, unsubstituted or substituted C.sub.1 --C.sub.8 --alkyl, aryl or for ar--C.sub.1 --C.sub.4 --alkyl, aryl or an being unsubstituted or substituted phenyl, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are the same or different and stand for hydrogen, halogen, pseudo halogen, cyano, nitro, amino, carboxy, carbalkoxy, carbamyl, hydroxy, alkyl, alkoxy; n and m are the same or different and stand for an integer from 0-6; provided that n cannot be zero when A stands for carboxy and X and Q both stand for a bond; X stands for a bond or for O, S, S(O), S(O).sub.2 or for NR.sub.8 where R.sub.8 is defined as R.sub.1 above; Q stands for a bond of for straight or branched, C.sub.1 --C.sub.6 --alkylene; A stands for an acidic group, e.g.
    Type: Grant
    Filed: June 1, 1990
    Date of Patent: May 5, 1992
    Assignee: Leo Pharmaceutical Products Ltd.
    Inventors: Ian Ahnfelt-Ronne, Erik T. Hansen, Dorte Kirstein, Ole Bent I. Nielsen, Schneur Rachlin
  • Patent number: 4293549
    Abstract: This invention relates to new compounds, salts, complexes and acylated derivatives thereof, methods of producing said compounds, intermediates used in the method, pharmaceutical compositions containing the present compounds and methods of producing same, and a method of treating patients using the present compounds, having the general formula (I) ##STR1## in which R.sub.1 represents hydrogen, alkyl, alkoxy, hydroxy, halogen, trifluoromethyl, or phenyl; R.sub.2 represents hydrogen, alkyl, alkoxy, halogen, trifluoromethyl, or hydroxy; R.sub.3 represents alkyl, cycloalkyl which can be further mono- or disubstituted with methyl or ethyl, phenyl or phenyl-alkyl, optionally being further substituted; and R.sub.
    Type: Grant
    Filed: October 27, 1978
    Date of Patent: October 6, 1981
    Assignee: Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktion-saktieselskab)
    Inventors: Schneur Rachlin, Edoardo Arrigoni-Martelli
  • Patent number: 3951957
    Abstract: New penicillin esters and their salts together with methods for, and intermediates in the preparation thereof, the esters having the formula: ##EQU1## in which formula the asterisk indicates the possibility of an asymmetric carbon atom, n indicates an integer from 0 to 5, R.sup.1 represents a group, which together with --CO-- forms the side chain of any of the known semisynthetic, biosynthetic, and natural penicillins; R.sup.2 has any of the following meanings: hydrogen, an aliphatic, an aromatic, a heterocyclic group, and an aromatically substituted aliphatic group; each of R.sup.3, R.sup.4, and R.sup.5 represents hydrogen, or a lower aliphatic group with the provision that R.sup.2 and R.sup.5 together with the carbon atom between them can form a 5-, 6-, or 7-membered carbocyclic ring, and either R.sup.3 and R.sup.4, or R.sup.4 and R.sup.5 together with the nitrogen atom can form a ring system.
    Type: Grant
    Filed: June 18, 1974
    Date of Patent: April 20, 1976
    Assignee: Lovens Kemiske Fabrik Produktionsaktieselskab
    Inventors: Welf von Daehne, Erling Knud Frederiksen, Wagn Ole Godtfredsen, Schneur Rachlin