Patents by Inventor Scot J. Stone

Scot J. Stone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diacylglycerol O-acyltransferase 2? (DGAT2?)
    Patent number: 7862819
    Abstract: Nucleic acid compositions encoding mammalian DGAT2? polypeptide products with diglyceride acyltransferase activity, as well as the mammalian DGAT2? polypeptide products encoded thereby and methods for producing the same, are provided. The subject DGAT2? polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications, as well as in treatment therapies and in the production of triacylglycerols.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: January 4, 2011
    Assignee: The J. David Gladstone Institutes
    Inventors: Sylvaine Cases, Robert V. Farese, Scot J. Stone, Ping Zhou
  • Mono- and diacylglycerol acyltransferases and methods of use thereof
    Patent number: 7045326
    Abstract: Nucleic acid compositions encoding polypeptide products with diglyceride acyltransferase and/or monoacylglycerol acyltransferase activity, as well as the polypeptide products encoded thereby, i.e., mammalian DGAT2? and MGAT1 polypeptide products, and methods for producing the same, are provided. Also provided are: methods and compositions for modulating DGAT2? and MGAT1 activity; DGAT2? and MGAT1 transgenic cells, animals and plants, as well as methods for their preparation; and methods for making diglyceride, diglyceride compositions, triglycerides and triglyceride compositions, as well as the compositions produced by these methods. The subject methods and compositions find use in a variety of different applications, including research, medicine, agriculture and industry applications.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: May 16, 2006
    Assignee: The Regents of the University of California
    Inventors: Sylvaine Cases, Scot J. Stone, Ping Zhou, Robert V. Farese, Jr., Chi-Liang Eric Yen
  • Diacylglycerol O-Acyltransferase 2a (DGAT2ALPHa)
    Publication number: 20030202968
    Abstract: Nucleic acid compositions encoding mammalian DGAT2&agr; polypeptide products with diglyceride acyltransferase activity, as well as the mammalian DGAT2&agr; polypeptide products encoded thereby and methods for producing the same, are provided. The subject DGAT2&agr; polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications, as well as in treatment therapies and in the production of triacylglycerols.
    Type: Application
    Filed: May 27, 2003
    Publication date: October 30, 2003
    Inventors: Sylvaine Cases, Robert V. Farese, Scot J. Stone, Ping Zhou
  • Mono-and diacylglycerol acyltransferases and methods of use thereof
    Publication number: 20030161831
    Abstract: Nucleic acid compositions encoding polypeptide products with diglyceride acyltransferase and/or monoacylglycerol acyltransferase activity, as well as the polypeptide products encoded thereby, i.e., mammalian DGAT2&agr;, MGAT1, or MGAT2 polypeptide products, and methods for producing the same, are provided. Also provided are: methods and compositions for modulating DGAT2&agr;, MGAT1, or MGAT2 activity; DGAT2&agr;, MGAT1, or MGAT2 transgenic cells, animals and plants, as well as methods for their preparation; and methods for making diglyceride, diglyceride compositions, triglycerides and triglyceride compositions, as well as the compositions produced by these methods. The subject methods and compositions find use in a variety of different applications, including research, medicine, agriculture and industry applications.
    Type: Application
    Filed: October 31, 2002
    Publication date: August 28, 2003
    Inventors: Sylvaine Cases, Scot J. Stone, Ping Zhou, Robert V. Farese, Chi-Liang Eric Yen
  • Mono-and diacylglycerol acyltransferases and methods of use thereof
    Publication number: 20030124126
    Abstract: Nucleic acid compositions encoding polypeptide products with diglyceride acyltransferase and/or monoacylglycerol acyltransferase activity, as well as the polypeptide products encoded thereby, i.e., mammalian DGAT2&agr; and MGAT1 polypeptide products, and methods for producing the same, are provided. Also provided are: methods and compositions for modulating DGAT2&agr; and MGAT1 activity; DGAT2&agr; and MGAT1 transgenic cells, animals and plants, as well as methods for their preparation; and methods for making diglyceride, diglyceride compositions, triglycerides and triglyceride compositions, as well as the compositions produced by these methods. The subject methods and compositions find use in a variety of different applications, including research, medicine, agriculture and industry applications.
    Type: Application
    Filed: January 14, 2002
    Publication date: July 3, 2003
    Inventors: Sylvaine Cases, Scot J. Stone, Ping Zhou, Robert V. Farese, Chi-Liang Eric Yen