Patents by Inventor Scott Armstrong

Scott Armstrong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12359427
    Abstract: The disclosure presents a composite conduit formwork structure which includes a cylindrical outer casing adapted to bond with a cylindrical inner casing which are maintained at a fixed distance apart by a plurality of radial stanchions. The inner casing and outer casing form an interior void which is filled with concrete during manufacture. The outer casing and inner casing remain in place to protect the structure once completed. A novel method of assembly is also provided whereby radial stanchions are rotated between the outer casing and inner casing. All of the components in a preferred embodiment are formed of a fiberglass material.
    Type: Grant
    Filed: February 27, 2023
    Date of Patent: July 15, 2025
    Assignee: Forma Technologies Inc.
    Inventor: Scott Armstrong
  • Patent number: 12331069
    Abstract: Provided herein are bifunctional compounds with a moiety or domain that is a binder of the ubiquitin receptor RPN13 and another moiety or domain that is a binder of a target protein DOT1L to induce degradation of DOT1L. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, such as cancers). Provided also are methods of inducing the degradation of DOT1L by administering a bifunctional compound or composition described herein, wherein one domain of the bifunctional compound is a binder of the ubiquitin receptor RPN13 and another domain of the compound is a binder of the target protein DOT1L in a subject.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: June 17, 2025
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Scott Armstrong, Jun Qi
  • Publication number: 20250092078
    Abstract: Compounds for activating invariant natural killer T cells (iNKT) cells are provided. Compounds according to certain embodiments activate iNKT cells and induce an increase in the production of one or more cytokines, such as IFN?, IL-2, IL-4, IL-6 and TNF?. In some embodiments, activated iNKT cells are used to selectively reduce the presence of or eliminate inflammatory senescent cells, such as senescent cells having an inflammatory secretome (SASP). Methods for activating iNKT cells by contacting an iNKT cell with an amount of the subject compounds and selectively reducing the presence of or eliminating senescent cells with activated iNKT cells are also described. Compositions for practicing the subject methods are also described.
    Type: Application
    Filed: May 2, 2024
    Publication date: March 20, 2025
    Applicant: Deciduous Therapeutics, Inc.
    Inventors: Matthew DUNCTON, Thomas BOBINSKI, Ajit SHAH, Naze Gul AVCI, Abhijit KALE, Rachel HATANO, John GALLOWAY, Scott ARMSTRONG, Robin MANSUKHANI, Jasmine DENNY
  • Publication number: 20250086602
    Abstract: A financial institution agnostic saving system including a server configured to (i) receive information for a funding source of a user at a first financial institution; (ii) receive information for a saving account of the user at a second financial institution; (iii) receive user saving target information for the user which includes a saving rule for determining when to transfer funds from the funding source to the saving account wherein the saving rule is defined based on an amount spent by the user; (iv) receive transaction information for a transaction by the user from a third financial institution, wherein the transaction information includes the amount spent by the user; and (v) transfer money from the funding source to the saving account according to the saving rule. The system may include a marketplace which allows users to modify user saving target information and/or make purchases with savings.
    Type: Application
    Filed: November 15, 2024
    Publication date: March 13, 2025
    Applicant: New World Savings, Inc.
    Inventors: Scott Armstrong, Ryan Armstrong
  • Publication number: 20250010161
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for providing a golf simulator comprising a computing system with real-life golf courses stored in memory, a projector, and a screen; projecting a simulation of a real-life golf hole stored in memory on the screen with the computing system to provide a simulated golf hole that simulates the real-life golf hole; and using one or more lights to indicate a location of the ball after a simulation of one or more golf shots.
    Type: Application
    Filed: September 26, 2024
    Publication date: January 9, 2025
    Inventors: Andrew Macaulay, Scott Armstrong, Michael M. McCarley
  • Publication number: 20240335438
    Abstract: Disclosed is a method of treating cancer with a compound that possesses degradation activity against SMARCA4/2 in combination with a DOT1L r inhibitor.
    Type: Application
    Filed: July 18, 2022
    Publication date: October 10, 2024
    Applicant: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Jun Qi, Lingling Dai, Florian Perner, Scott Armstrong
  • Patent number: 12102900
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for providing a golf simulator comprising a computing system with real-life golf courses stored in memory, a projector, and a screen; projecting a simulation of a real-life golf hole stored in memory on the screen with the computing system to provide a simulated golf hole that simulates the real-life golf hole; and using one or more lights to indicate a location of the ball after a simulation of one or more golf shots.
    Type: Grant
    Filed: February 5, 2024
    Date of Patent: October 1, 2024
    Assignee: TMRW Sports, Inc.
    Inventors: Andrew Macaulay, Scott Armstrong, Michael M. McCarley
  • Publication number: 20240173605
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for providing a golf simulator comprising a computing system with real-life golf courses stored in memory, a projector, and a screen; projecting a simulation of a real-life golf hole stored in memory on the screen with the computing system to provide a simulated golf hole that simulates the real-life golf hole; and using one or more lights to indicate a location of the ball after a simulation of one or more golf shots.
    Type: Application
    Filed: February 5, 2024
    Publication date: May 30, 2024
    Inventors: Andrew Macaulay, Scott Armstrong, Michael M. McCarley
  • Publication number: 20240037888
    Abstract: A camera system may capture object activity with a field of view comprising one or more regions and identify and selectively output captured image data based on the one or more regions.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 1, 2024
    Inventors: Peter Lester, Arun Ravisankar, Arpit Mathur, Scott Armstrong, Julianne Heinzmann, Resmi Vijayan, Andrew Posmontier
  • Publication number: 20240025936
    Abstract: Compounds for activating invariant natural killer T cells (iNKT) cells are provided. Compounds according to certain embodiments activate iNKT cells and induce an increase in the production of one or more cytokines, such as IFN-?, IL-2, IL-4, IL-6 and TNF?. In some embodiments, activated iNKT cells are used to selectively reduce the presence of or eliminate inflammatory senescent cells, such as senescent cells having an inflammatory secretome (SASP). Methods for activating iNKT cells by contacting an iNKT cell with an amount of the subject compounds and selectively reducing the presence of or eliminating senescent cells with activated iNKT cells are also described. Compositions for practicing the subject methods are also described.
    Type: Application
    Filed: August 30, 2023
    Publication date: January 25, 2024
    Applicant: Deciduous Therapeutics, Inc.
    Inventors: Matthew Duncton, Thomas Bobinski, Ajit Shah, Naze Gul AVCI, Abhijit Kale, Rachel Hatano, John Galloway, Scott Armstrong, Robin Mansukhani, Jasmine Denny
  • Patent number: 11739526
    Abstract: The disclosure presents a composite concrete structure formwork which comprises stay in place fiberglass profiles and reinforcement to form various building and shelter structures. The structures include an interior container maintained at a set distance within an exterior container to form a void. The void is filled with wet concrete which is allowed to cure. All of the components in a preferred embodiment are formed of a fiberglass material.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: August 29, 2023
    Assignee: Forma Technologies Inc.
    Inventor: Scott Armstrong
  • Patent number: 11739525
    Abstract: The disclosure presents a composite column formwork which utilizes a fiber reinforced polymer (FRP) stay in place container which incorporates horizontally coplanar support chairs bonded to the interior surface, closed ties bonded to the support chairs and a plurality of longitudinal rebar enforcements bonded to the closed ties. All of the components in a preferred embodiment are formed of a fiberglass material.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: August 29, 2023
    Assignee: Forma Technologies Inc.
    Inventor: Scott Armstrong
  • Publication number: 20230203809
    Abstract: The disclosure presents a composite conduit formwork structure which includes a cylindrical outer casing adapted to bond with a cylindrical inner casing which are maintained at a fixed distance apart by a plurality of radial stanchions. The inner casing and outer casing form an interior void which is filled with concrete during manufacture. The outer casing and inner casing remain in place to protect the structure once completed. A novel method of assembly is also provided whereby radial stanchions are rotated between the outer casing and inner casing. All of the components in a preferred embodiment are formed of a fiberglass material.
    Type: Application
    Filed: February 27, 2023
    Publication date: June 29, 2023
    Applicant: Forma Technologies Inc.
    Inventor: Scott Armstrong
  • Patent number: 11634450
    Abstract: Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety that is a binder of a target protein DOT1L to induce degradation of DOT1L. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, such as cancers). Provided also are methods of inducing the degradation of DOT1L by administering a bifunctional compound or composition described herein, wherein one component of the bifunctional compound is a binder of an E3 ubiquitin ligase (e.g., lenalidomide, thalidomide) and another component of the compound is a binder of the target protein DOT1L in a subject.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: April 25, 2023
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Jun Qi, Scott Armstrong, Paul M. Park
  • Patent number: 11591793
    Abstract: The disclosure presents a composite conduit formwork structure which includes a cylindrical outer casing adapted to bond with a cylindrical inner casing which are maintained at a fixed distance apart by a plurality of radial stanchions. The inner casing and outer casing form an interior void which is filled with concrete during manufacture. The outer casing and inner casing remain in place to protect the structure once completed. A novel method of assembly is also provided whereby radial stanchions are rotated between the outer casing and inner casing. All of the components in a preferred embodiment are formed of a fiberglass material.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: February 28, 2023
    Assignee: Forma Technologies Inc.
    Inventor: Scott Armstrong
  • Patent number: 11542704
    Abstract: The disclosure presents a reconfigurable composite floor formwork which defined by a plurality of interlocking fiberglass panels formed into profiles which may be moved and adapted to provide a concrete form for a floor or ceiling. All of the components in a preferred embodiment are formed of a fiberglass material.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: January 3, 2023
    Assignee: Forma Technologies Inc.
    Inventor: Scott Armstrong
  • Patent number: 11525260
    Abstract: The disclosure presents a formwork system which utilizes Fiber Reinforced Polymer (FRP) panels to create modular segments to form and reinforce concrete subgrade structures. The segments may be rearranged and bonded together to conform to intended dimensions of many subgrade structures. The segments are manufactured by cast molding, bonding or vacuum forming. The segments may include integrated FRP stanchions to prevent deflection of the panels during concrete placement. The stanchions also may be used for positioning structural steel or FRP rebar. FRP bars are permanently bonded to the interior sides of the panels inside the segments. In use, the assembled segments are filled with concrete. After the concrete is cured, the segments remain in place and function as external protection and reinforcement for the cured concrete.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: December 13, 2022
    Assignee: Forma Technologies Inc.
    Inventor: Scott Armstrong
  • Publication number: 20220389023
    Abstract: Disclosed herein are compounds that target SMARCA2 and SMARCA4, causing their degradation. Also disclosed herein are compositions and methods of use in treating associated disorders and diseases.
    Type: Application
    Filed: June 25, 2020
    Publication date: December 8, 2022
    Applicant: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Jun Qi, Scott Armstrong, Lei Wu
  • Publication number: 20220343300
    Abstract: A financial institution agnostic saving system including a server configured to (i) receive information for a funding source of a user at a first financial institution; (ii) receive information for a saving account of the user at a second financial institution; (iii) receive user saving target information for the user which includes a saving rule for determining when to transfer funds from the funding source to the saving account wherein the saving rule is defined based on an amount spent by the user; (iv) receive transaction information for a transaction by the user from a third financial institution, wherein the transaction information includes the amount spent by the user; and (v) transfer money from the funding source to the saving account according to the saving rule. The system may include a marketplace which allows users to modify user saving target information and/or make purchases with savings.
    Type: Application
    Filed: April 22, 2022
    Publication date: October 27, 2022
    Inventors: Scott Armstrong, Ryan Armstrong
  • Publication number: 20220307031
    Abstract: The presently disclosed subject matter relates to the administration of a KMT2D inhibitor for the treatment of a cancer. The present invention is based on the discovery that upon PI3K inhibition, KMT2D activity is upregulated, resulting in an increase in the expression of genes involved in breast cancer cell proliferation and tumor growth. Accordingly, the present invention provides methods for treating a subject that has cancer by administering a therapeutically effective amount of an KMT2D inhibitor.
    Type: Application
    Filed: February 10, 2022
    Publication date: September 29, 2022
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Jose Baselga, Eneda Toska, Scott Armstrong