Patents by Inventor Scott A. Conradson

Scott A. Conradson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190194734
    Abstract: A method of screening for at least one biological entity of interest using a microfabricated device which has a top surface defining an array of microwells. A sample is loaded onto the microfabricated device such that at least one microwell of the array of microwells includes at least one cell and an amount of a nutrient. A membrane is applied to the microfabricated device to retain the at least one cell and the nutrient. A plurality of cells are cultured from the at least one cell in the at least one microwell of the array of microwells. The plurality of cells is then analyzed to determine a presence or absence of a biological entity of interest.
    Type: Application
    Filed: December 27, 2018
    Publication date: June 27, 2019
    Inventors: Paul C. Blainey, Michael W. Seely, Roman Stocker, Karsten Zengler, Scott Conradson, Peter Christey, Alexander Hallock
  • Publication number: 20190194736
    Abstract: A kit includes a microfabricated device having a top surface defining an array of microwells for receiving a sample comprising at least one cell, and a membrane for applying on the top surface of the microfabricated device to retain the at least one cell in at least one microwell of the array of microwells after the sample is loaded on the microfabricated device.
    Type: Application
    Filed: December 27, 2018
    Publication date: June 27, 2019
    Inventors: Paul C. Blainey, Michael W. Seely, Roman Stocker, Karsten Zengler, Scott Conradson, Peter Christey, Alexander Hallock
  • Publication number: 20190194735
    Abstract: A method of screening for at least one biological entity of interest using a microfabricated device which has a top surface defining an array of microwells. A sample is loaded onto the microfabricated device such that at least one microwell of the array of microwells includes at least one cell and an amount of a nutrient. A membrane is applied to the microfabricated device to retain the at least one cell and the nutrient. A plurality of cells is cultured from the at least one cell in the at least one microwell of the array of microwells. The plurality of cells in the at least one microwell of the array of microwells are split into a first portion of the plurality of cells and a second portion of the plurality of cells. The plurality of cells is analyzed to determine a presence or absence of a biological entity of interest.
    Type: Application
    Filed: December 27, 2018
    Publication date: June 27, 2019
    Inventors: Paul C. Blainey, Michael W. Seely, Roman Stocker, Karsten Zengler, Scott Conradson, Peter Christey, Alexander Hallock
  • Patent number: 10227640
    Abstract: A method of screening for at least one biological entity of interest using a microfabricated device which has a top surface defining an array of microwells. A sample is loaded onto the microfabricated device such that at least one microwell of the array of microwells includes at least one cell and an amount of a nutrient. A membrane is applied to the microfabricated device to retain the at least one cell and the nutrient. Without furnishing additional nutrient to the microwells, the microfabricated device is incubated to grow a plurality of cells from the at least one cell in the at least one microwell of the array of microwells. The plurality of cells is then analyzed to determine a presence or absence of a biological entity of interest.
    Type: Grant
    Filed: September 30, 2017
    Date of Patent: March 12, 2019
    Assignee: GENERAL AUTOMATION LAB TECHNOLOGIES, INC.
    Inventors: Paul C. Blainey, Michael W. Seely, Roman Stocker, Karsten Zengler, Scott Conradson, Peter Christey, Alexander Hallock
  • Publication number: 20180100194
    Abstract: Accordingly, in some embodiments methods for detecting an analyte or analytes in one or more sample(s) are provided. The methods encompass providing a solid support with an addressable marker and an associated ligand, contacting the solid substrate to a sample, thereby forming a contacted solid support, associating the contacted solid support with a FET array and detecting the electrical properties of the FET array and thereby detecting an analyte or analytes in one or more samples. In other embodiments, the sample encompasses a second addressable marker.
    Type: Application
    Filed: December 18, 2017
    Publication date: April 12, 2018
    Inventors: Scott Conradson, David Dinauer, Bin Zhao, Dmitriy Gremyachinskiy, Jason Myers, Jeffrey Rossio, Victoria Singer, Kristina Giorda
  • Publication number: 20180051327
    Abstract: A method of screening for at least one biological entity of interest using a microfabricated device which has a top surface defining an array of microwells. A sample is loaded onto the microfabricated device such that at least one microwell of the array of microwells includes at least one cell and an amount of a nutrient. A membrane is applied to the microfabricated device to retain the at least one cell and the nutrient. Without furnishing additional nutrient to the microwells, the microfabricated device is incubated to grow a plurality of cells from the at least one cell in the at least one microwell of the array of microwells. The plurality of cells is then analyzed to determine a presence or absence of a biological entity of interest.
    Type: Application
    Filed: September 30, 2017
    Publication date: February 22, 2018
    Inventors: Paul C. Blainey, Michael W. Seely, Roman Stocker, Karsten Zengler, Scott Conradson, Peter Christey, Alexander Hallock
  • Patent number: 9885083
    Abstract: Accordingly, in some embodiments methods for detecting an analyte or analytes in one or more sample(s) are provided. The methods encompass providing a solid support with an addressable marker and an associated ligand, contacting the solid substrate to a sample, thereby forming a contacted solid support, associating the contacted solid support with a FET array and detecting the electrical properties of the FET array and thereby detecting an analyte or analytes in one or more samples. In other embodiments, the sample encompasses a second addressable marker.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: February 6, 2018
    Assignee: Life Technologies Corporation
    Inventors: Scott Conradson, David Dinauer, Bin Zhao, Dmitriy Gremyachinskiy, Jason Myers, Jeffrey Rossio, Victoria Singer, Kristina Giorda
  • Publication number: 20160312275
    Abstract: A microfabricated device defining a high density array of microwells is described for cultivating cells from a sample. A series of unique tags may be disposed in the microwells to identify one or more species of cells and locate the particular microwells in which each species was cultivated. A unique tag may be a nucleic acid molecule including a target-specific nucleotide sequence for annealing to a target nucleic acid fragment and a location-specific nucleotide sequence predetermined to identify one or more microwells. The device may be incubated to grow a plurality of cells, which may be split into an analysis portion and a reserve portion. High throughput methods are described for cultivating, screening, and determining a relative and/or absolute abundance of cells from a sample.
    Type: Application
    Filed: April 21, 2016
    Publication date: October 27, 2016
    Inventors: Paul C. Blainey, Michael W. Seely, Roman Stocker, Karsten Zengler, Scott Conradson, Peter Christey, Alexander Hallock
  • Publication number: 20150203912
    Abstract: Accordingly, in some embodiments methods for detecting an analyte or analytes in one or more sample(s) are provided. The methods encompass providing a solid support with an addressable marker and an associated ligand, contacting the solid substrate to a sample, thereby forming a contacted solid support, associating the contacted solid support with a FET array and detecting the electrical properties of the FET array and thereby detecting an analyte or analytes in one or more samples. In other embodiments, the sample encompasses a second addressable marker.
    Type: Application
    Filed: June 25, 2013
    Publication date: July 23, 2015
    Inventors: Scott Conradson, David Dinauer, Bin Zhao, Dmitriy Gremyachinskiy, Jason Myers, Jeffrey Rossio, Victoria Singer, Kristina Glorda
  • Publication number: 20050149418
    Abstract: Methods and systems for providing information to a mortgage recipient or other customer of a financial institution. A system identifies potential customer inquiries and provides a list of scripts responsive to the potential customer inquiries. If none of the scripts address the customer's inquiry, the customer specifies the inquiry and an additional list of scripts is generated. The scripts include scripted text, account information, and financial transaction information. In one variation, the customer accesses a website maintained by the financial institution and views a script responsive to the inquiry. In another variation, the customer telephones a customer service agent who selects a script responsive to the inquiry, and reads the script to the customer. In yet another variation, the script is provided to the customer via an Interactive Voice Response system.
    Type: Application
    Filed: August 16, 2004
    Publication date: July 7, 2005
    Inventors: William Erbey, Scott Conradson
  • Patent number: 5677197
    Abstract: An assay system for detecting the binding of a mobile reactant to an immobilized reactant on an assay plate. The assay plate includes a substrate having an assay spot deposited thereon. The assay spot includes the immobilized reactant. In the present invention, a carrier dye is included in the assay spot, the amount of the carrier dye indicating the amount of the immobilized reactant that is present in the assay spot. In the preferred embodiment of the present invention, the assay spot is generated by depositing liquid on the assay plate at a location corresponding to the assay spot. The carrier dye is dissolved in the liquid and remains after the liquid evaporates. The amount of carrier dye in each spot may be measured spectroscopically and provides a means for identifying defective assay plates.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: October 14, 1997
    Assignee: Hewlett-Packard Company
    Inventors: Gary B. Gordon, Scott A. Conradson, Kay Lichtenwalter
  • Patent number: 5601980
    Abstract: A method and apparatus is provided for spotting a biological probe onto an array. A micropipette containing a quantity of the biological probe in solution is manipulated to a position above a selected location within the array. The micropipette is pressurized sufficiently to produce a droplet of the biological probe at an open tip of the micropipette. Formation of the droplet is simultaneously visually monitored during the pressurization of the micropipette in order to estimate a volume measurement of the droplet. Upon reaching a predetermined volume for the droplet, the pressurizing of the micropipette is discontinued. The droplet of the predetermined volume is then dispensed onto the selected location.
    Type: Grant
    Filed: September 23, 1994
    Date of Patent: February 11, 1997
    Assignee: Hewlett-Packard Company
    Inventors: Gary B. Gordon, Scott A. Conradson, Kay Lichtenwalter
  • Patent number: 5587914
    Abstract: A CAD system and method for designing sheet metal parts. A proposed design is automatically tested against a set of design rules. Available tools are selected according to criteria computed with reference to the part to the fabricated and then are tested to determine whether they can be used to make desired bends. A fabrication sequence is computed.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: December 24, 1996
    Assignee: Hewlett-Packard Company
    Inventors: Scott A. Conradson, Lee A. Barford, William D. Fisher, Michael J. Weinstein, Julie D. Wilker
  • Patent number: 5551487
    Abstract: A method and apparatus for dispensing immobilized reactants onto substrates for use in generating a biological assay plate for detecting the presence of mobile reactants that bind to the immobilized reactants. The apparatus includes a dispensing bed that holds a plurality of substrates. Each potential immobilized reactant is held in a cartridge. The apparatus includes a holder that allows any of these cartridges to be used in dispensing an immobilized reactant. The apparatus includes a positioning mechanism for positioning the cartridges over each of the substrates. The positioning mechanism also allows a cartridge so positioned to be brought into contact with each of the substrates at a predetermined location on each of the substrates so as to dispense a known quantity of the immobilized reactant onto the substrate at that location.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: September 3, 1996
    Assignee: Hewlett-Packard Company
    Inventors: Gary B. Gordon, Scott A. Conradson, Kay Lichtenwalter
  • Patent number: 5307282
    Abstract: A CAD system and method for designing sheet metal parts. A proposed design is automatically tested against a set of design rules. Available tools are selected according to criteria computed with reference to the part to the fabricated and then are tested to determine whether they can be used to make desired bends. A fabrication sequence is computed.
    Type: Grant
    Filed: November 6, 1989
    Date of Patent: April 26, 1994
    Assignee: Hewlett-Packard Company
    Inventors: Scott A. Conradson, Lee A. Barford