Abstract: The present disclosure provides devices, methods and systems for analyte detection and/or monitoring, e.g., the continuous and/or semi-continuous monitoring of in-vivo analyte concentrations in real time. Generally, the devices, methods and systems of the present disclosure make use of signaling probes; methods or devices for reducing interferent-based fouling of the signaling probes, non-specific binding to the signaling probes and/or occlusion of a sensor surface; and methods and/or devices for providing an adjusted signal based on a detected signal from the signaling probes. Compositions including conformation switching signaling probes are also provided.

Abstract: In general, techniques are described for managing content request referrals by keying content requests to a composite key data structure that maps end-user address prefixes and content identifiers to content delivery network servers of downstream CDNs. In one example, a CDN exchange includes a communication module to receive first network prefixes and first content identifiers from a first secondary content delivery network and to receive second network prefixes and second content identifiers from a second secondary content delivery network. A request router of the CDN exchange redirects the content request to the first secondary content delivery network or to the second secondary content delivery network according to a network address of the end user device and a content identifier for the content request.

Abstract: In general, techniques are described for managing content request referrals by keying content requests to a composite key data structure that maps end-user address prefixes and content identifiers to content delivery network servers of downstream CDNs. In one example, a CDN exchange includes a communication module to receive first network prefixes and first content identifiers from a first secondary content delivery network and to receive second network prefixes and second content identifiers from a second secondary content delivery network. A request router of the CDN exchange redirects the content request to the first secondary content delivery network or to the second secondary content delivery network according to a network address of the end user device and a content identifier for the content request.

Abstract: Various embodiments of the present disclosure generally provide a drive link for a saw chain including a body portion adapted to couple to adjacent side links and a tang extending from the body and sized to engage a guide bar groove. The tang may include a through hole extending from a first tang side to a second tang side and including a through hole center. In various embodiments, a material directing feature may be disposed adjacent to the through hole on at least one of the first side and second side of the tang. The material directing feature may include a recession in the tang which encourages oil and/or wood chips to pass through the through hole.

Abstract: The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminantium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.

Abstract: A replacement stretch type boot is applied to the tie rod shaft of a steering rack assembly using an application aid consisting of a sleeve of flexible sheet material which is applied over the tie rod end to provide a smooth surface for passage of the boot over the tie rod end.

Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.

Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.

Abstract: A method for measuring a chemical concentration in tissue has two measurement steps. A portion of tissue is illuminated with a first generated light and a second generated light. A first Raman scattered light, corresponding to the first generated light, and a second Raman scattered light, corresponding to the second generated light, are directed to a plurality of light sensors, each light sensor measuring light at a different wavelength, that wavelength being proximate to a wavelength of an expected Raman shift wavelength for the chemical in the tissue. A measurement is obtained from each light sensor, each measurement being specific to the first scattered light and/or the second reflected light to that light sensor. The measurements of the first scattered light and the measurements of the second scattered light are used to calculate a concentration of the chemical in the tissue.

Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.

Abstract: Photovoltaic elements can be formed by in-motion processing of a silicon ribbon. In some embodiments, only a single surface of a silicon ribbon is processed in-motion. In other embodiments both surfaces of a silicon ribbon is processed in-motion. In-motion processing can include, but is not limited to, formation of patterned or uniform doped regions within or along the silicon ribbon as well as the formation of patterned or uniform dielectric layers and/or electrically conductive elements on the silicon ribbon. After performing in-motion processing, additional processing steps can be performed after the ribbon is cut into portions. Furthermore, post-cut processing can include, but is not limited to, the formation of solar cells, photovoltaic modules, and solar panels.

Abstract: Various embodiments of the present disclosure generally provide a drive link for a saw chain including a body portion adapted to couple to adjacent side links and a tang extending from the body and sized to engage a guide bar groove. The tang may include a through hole extending from a first tang side to a second tang side and including a through hole center. In various embodiments, a material directing feature may be disposed adjacent to the through hole on at least one of the first side and second side of the tang. The material directing feature may include a recession in the tang which encourages oil and/or wood chips to pass through the through hole.

Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.

Abstract: A VOIP PBX configuration system and method enable remotely configuring a VOIP PBX server connected to the Internet. The system includes a central server connected to the Internet and having a database of VOIP PBX configuration templates. The central server is accessible via a website user interface having configuration fields to be populated by a user. The central server includes computer readable program code components configured to modify the configuration templates to generate configuration instructions based on user entries in the configuration fields, and transmit the configuration instructions to the VOIP PBX server to configure the VOIP PBX server based on the user entries.

Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.

Abstract: A method for measuring a chemical concentration in tissue has two measurement steps. A portion of tissue is illuminated with a first generated light and a second generated light. A first Raman scattered light, corresponding to the first generated light, and a second Raman scattered light, corresponding to the second generated light, are directed to a plurality of light sensors, each light sensor measuring light at a different wavelength, that wavelength being proximate to a wavelength of an expected Raman shift wavelength for the chemical in the tissue. A measurement is obtained from each light sensor, each measurement being specific to the first scattered light and/or the second reflected light to that light sensor. The measurements of the first scattered light and the measurements of the second scattered light are used to calculate a concentration of the chemical in the tissue.

Abstract: A method of accounting for errors in the altitude reporting of a terrain alert and warning system (TAWS) is disclosed wherein errors due to non-standard atmospheric conditions, incorrect altimeter setting and air data computer (ADC) sensor error are detected and corrected for by compensating ADC altitudes for cold temperatures as well as using global positioning system (GPS) altitude data to confirm the accuracy of the ADC altitude information at all times.

Abstract: A method for measuring a chemical concentration in tissue has two measurement steps. A portion of tissue is illuminated with a first generated light and a second generated light. A first Raman scattered light, corresponding to the first generated light, and a second Raman scattered light, corresponding to the second generated light, are directed to a plurality of light sensors, each light sensor measuring light at a different wavelength, that wavelength being proximate to a wavelength of an expected Raman shift wavelength for the chemical in the tissue. A measurement is obtained from each light sensor, each measurement being specific to the first scattered light and/or the second reflected light to that light sensor. The measurements of the first scattered light and the measurements of the second scattered light are used to calculate a concentration of the chemical in the tissue.

Abstract: Apparatus and method for separating individual human reproductive material from a fertilization dish and storing the material in a cryotank for future fertilization and implantation. The apparatus includes an elongate cryostraw having a first open end and second heat-sealable open end, a channel extending between said ends, and an internal, calibrated volume VC. A displacement bulb is connected to the first end of the cryostraw for admitting and emitting the material into said cryostraw. The bulb has a total volume VB1, an internal cavity with a compressible end volume VB2, a first seal with the first end of said cryostraw; and, means for limiting the intake volume displacement produced in said cryostraw to an amount less than VC no matter how far the bulb is squeezed. The bulb produces less than a unit volume of displacement in the cryostraw when the bulb is squeezed and its volume VB1 is reduced by a unit volume.

Abstract: A fluidic device employs one or more sorting stations for separating target species from other species in a sample. At least one of the sorting stations employs a magnetic field gradient to accomplish separation. In addition, the sorting station is integrated on a single substrate with one or more other modules for processing the sample. For example, the fluidic device may include both a sorting station and a separate trapping station that holds some or all components of the sample for additional processing. The trapping station may be located at a position upstream or downstream from the sorting module.