Abstract: A user interface can display a rendering associated with an interactive layer corresponding to one or more rendered elements of the rendering. Based at least partly on receiving an indication of an interaction with the user interface, a new rendered element can be displayed on the user interface. Based at least in part on information associated with the one or more rendered elements, a position in the interactive layer closest to a position of the new rendered element on the user interface can be determined and a rendered marking can be displayed at or near the position in the interactive layer that is closest to the position of the new rendered element. Based at least in part on a determination that the new rendered element is to be positioned at or near the position in the interactive layer, the rendering can be updated.

Abstract: A user interface can display a rendering associated with an interactive layer corresponding to one or more rendered elements of the rendering. Based at least partly on receiving an indication of an interaction with the user interface, a new rendered element can be displayed on the user interface. Based at least in part on information associated with the one or more rendered elements, a position in the interactive layer closest to a position of the new rendered element on the user interface can be determined and a rendered marking can be displayed at or near the position in the interactive layer that is closest to the position of the new rendered element. Based at least in part on a determination that the new rendered element is to be positioned at or near the position in the interactive layer, the rendering can be updated.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A native overlay for enabling rapid editing of web content is described. In an example, a web page comprising a plurality of visual elements can be rendered as a rendered web page which can be displayed on a user interface. In an example, responsive to an interaction via the user interface, a representation of a portion of the rendered web page can be generated, wherein the representation is positioned within an overlay displayed above the rendered web page. The rendered web page can be displayed with the representation positioned within the overlay on the user interface.

Abstract: Systems and methods permit customers to purchase resource instances on a spot purchasing mode basis, which permits a customer to specify a maximum price that the customer is willing to pay for one or more resource instances (e.g., virtual machine instances running on physical servers). Further, the resource instances purchased under the spot purchasing mode can be guaranteed to run for at least a specified period of time, even if the current variable spot cost value is exceeds the original bid price. Such instances run for defined blocks of time which may be selectable by the customer, thereby providing the customer some level of assurance that the instances will not terminate prematurely due to spot cost value fluctuations. Instances are assigned into a spot block instance pool from other types of pool based on the estimated excess capacity of such other types of pools. The estimate of excess capacity is based on statistical analysis of the usage of the instances.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: A web rendering module in the operating system is used to render and display a web page. The web rendering module also generates layout data that describes the position and size of each visual element on the rendered web page. A web editing application uses the layout data to generate a native overlay. The native overlay is an arrangement of cells, and each cell has the same position and size as a respective visual element. The application displays the native overlay on top of the rendered web page so that each visual element on the web page is aligned with a cell in the native overlay. The cells in the native overlay are transparent so that the rendered web page remains visible to the user, but the native overlay captures any interactions that the user performs. The interactions are then processed to make a corresponding change to the web page.

Abstract: The present invention includes three-dimensional models of complexes between antibody receptor proteins, such as Fc?RI? proteins, and antibodies, such as Fc-C?3/C?4 regions of IgE antibodies, as well as methods to produce such models. The present invention also includes muteins having increased stability and/or antibody binding activity, as well as methods to produce such muteins, preferably using information derived from three-dimensional models of the present invention. Also included are nucleic acid sequences encoding muteins of the present invention and use of those sequences to produce such muteins. Also included is the use of the model to identify compounds that inhibit the binding of an antibody receptor protein to an antibody. The present invention also includes uses of such muteins and inhibitory compounds, for example, in methods to diagnose and protect animals from allergy and other abnormal immune responses.