Abstract: A high-voltage (HV) system is provided including at least one HV component, a passive resistance load coupled to the at least one HV component, a control circuit coupled to the passive resistance load, and an isolated power supply coupled to the control circuit. The control circuit is switchable between a first state in which the control circuit closes an electric circuit connecting the at least one HV component and the passive resistance load and a second state in which the control circuit opens the electric circuit connecting the at least one HV component and the passive resistance load. The isolated power supply controls the control circuit to be in one of the first state and the second state.

Abstract: An off-trigger safety training device for firearms and method of use. The off-trigger safety training device is removably attached to a firearm proximal to a trigger of the firearm. The off-trigger safety training device is positioned for longitudinal alignment with a barrel of the firearm and includes a concave recess oriented in alignment with the barrel of the firearm for receiving the operator's trigger finger. Longitudinally extending ribs protrude from a face of the concave recess permit the user to align their finger within the concave recess and receive a complementary longitudinal tactile engagement with the ribs for positive engagement of the trigger finger with the off-trigger safety training device.

Abstract: A method of making an article of footwear is disclosed. The method may include the steps of selecting a family of article types, selecting a customized article type, manufacturing an article of footwear with the customized article type and shipping the article of footwear to a pre-designated shipping address. The customized article type can be configured with a user selected characteristic. The method can also include limiting the number of article types displayed to a user at any time.

Abstract: An electrically powered vehicle system includes a DC/DC converter stage with a rectified input terminal which receives a rectified input from an AC power input. The system also includes a vehicle battery which receives power output from the DC/DC converter stage, via a first link between the rectified input terminal and the DC/DC converter stage. A second link is connected to the first link and to a vehicle device.

Abstract: A vehicle electrical system including a battery, the terminals of which supply positive and negative power rails, the battery being connected to one or more vehicle devices to supply power or charging thereto. The devices include capacitors. The system also includes at least one heating device and a switch to allow capacitor discharge to flow through the heating device.

Abstract: An electrically powered vehicle system including a battery, the terminals of which supply positive and negative power rails, and including a bulk capacitor located in series with a switching device, and being electrically connected between the power rails. A heater having a heating resistance is connected in series with a heater switch, and is electrically connected between the power rails. A link is electrically connected between a point between the bulk capacitor and the switching device to a point between heating resistance and the heater switch.

Abstract: An electrically powered vehicle system includes a DC/DC converter stage with a rectified input terminal which receives a rectified input from an AC power input. The system also includes a vehicle battery which receives power output from the DC/DC converter stage, via a first link between the rectified input terminal and the DC/DC converter stage. A second link is connected to the first link and to a vehicle device.

Abstract: An electrically powered vehicle system including a battery, the terminals of which supply positive and negative power rails, and including a bulk capacitor located in series with a switching device, and being electrically connected between the power rails. A heater having a heating resistance is connected in series with a heater switch, and is electrically connected between the power rails. A link is electrically connected between a point between the bulk capacitor and the switching device to a point between heating resistance and the heater switch.

Abstract: A vehicle electrical system including a battery, the terminals of which supply positive and negative power rails, the battery being connected to one or more vehicle devices to supply power or charging thereto. The devices include capacitors. The system also includes at least one heating device and a switch to allow capacitor discharge to flow through the heating device.

Abstract: The invention discloses 155 novel phosphorylation sites identified in carcinoma and leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.

Abstract: The invention discloses 155 novel phosphorylation sites identified in carcinoma and leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.

Abstract: Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques.

Abstract: Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques.

Abstract: Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques.

Abstract: Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques.

Abstract: Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques.

Abstract: Analytical reagents and mass spectrometry-based methods using these reagents for the rapid, and quantitative analysis of proteins or protein function in mixtures of proteins. The methods employ affinity labeled protein reactive reagents having three portions: an affinity label (A) covalently linked to a protein reactive group (PRG) through a linker group (L). The linker may be differentially isotopically labeled, e.g., by substitution of one or more atoms in the linker with a stable isotope thereof. These reagents allow for the selective isolation of peptide fragments or the products of reaction with a given protein (e.g., products of enzymatic reaction) from complex mixtures. The isolated peptide fragments or reaction products are characteristic of the presence of a protein or the presence of a protein function in those mixtures. Isolated peptides or reaction products are characterized by mass spectrometric (MS) techniques.