Abstract: According to one aspect, a packaging includes a first panel including a first end and a second end, wherein first and second opposing perimeter side edges define the first panel and extend between the first end and the second end, and a first area having an inside surface is defined by the first end, the second end, and the perimeter side edges. A second panel includes a third end and a fourth end, wherein third and fourth opposing perimeter side edges define the second panel and extend between the third end and the fourth end, a second area having an inside surface is defined by the third end, the fourth end, and the perimeter side edges and wherein the second end is coupled to the third end at a first fold line. First and second tongues extend from third and fourth opposing perimeter side edges, respectively, at second and third fold lines, respectively.

Abstract: The present invention is directed to bioresorbable polymers to be used as bone and tissue adhesives. The present invention is also directed to the synthesis of bioresorbable polymeric molecules bearing adhesive moieties and the use of such compounds in methods to glue and stabilize fractured bones and damaged tissues. The present invention is also directed to the use of such compounds as adhesive sealants for applications in wound care. The present invention is also directed to the use of such compounds as biodegradable ink for applications in tissue engineering and 3D printing. The present invention also relates to the use of such compounds as drug delivery platforms.

Abstract: A beverage container may comprise a beverage container lid assembly comprising at least one concentrate well to hold a concentrate vessel, a concentrate vessel retainer for each concentrate well to secure the concentrate vessel in the concentrate well, a feed line for each concentrate well comprising a feed line needle to puncture the concentrate vessel in the at least one concentrate well, a Venturi mixer in fluid communication with each feed line, a mixing valve in fluid communication with each feed line, wherein fluid flows from the concentrate vessel to the Venturi mixer when the mixing valve is open and the concentrate vessel is punctured by the feed line needle. Methods of using the beverage container and beverage container lid assembly are also described.

Abstract: A polyaxial pedicle screw includes a housing, a bone screw member, and an anvil. The bone screw member includes a head and a threaded shaft extending from the head. The head is selectively securable within the housing. The anvil is positionable within the housing adjacent to the head of the bone screw member when the anvil and the head of the bone screw member are positioned within the housing. The anvil may define one or more grooves in an outer surface of the anvil. The groove defines a flap that is flexibly attached to the anvil to enable the anvil to flex an amount sufficient to maintain the head of the bone screw in constant contact with the anvil when the bone screw member is moved relative to the anvil. A rod reducer may be secured to the polyaxial pedicle screw to secure a spinal rod within the housing.

Abstract: According to one aspect, a packaging comprises a substrate comprising a first panel including a first end, a second end spaced a first distance from the first end, and opposing first and second perimeter side edges extending the first distance between the first end and the second end. The entire first panel is symmetric about a first longitudinal axis thereof extending between the first end and the second end and each of the first and second perimeter side edges is disposed at first and second widths, respectively, from the first longitudinal axis at a first portion of the first panel. The first portion is disposed at least one of at the second end and proximal the second end and the first portion has a longitudinal extent along the first longitudinal axis less than the first distance.

Abstract: The self-contained force magnifying tool disclosed herein includes a tool portion, a striker, at least a portion of which is disposed within the tool portion, and a spring, a least a portion of which is disposed within the tool portion. The spring attaches to both the tool portion and the striker. When the striker is pulled by a user, the spring stores mechanical energy. When the user releases the striker, the striker impacts on the tool portion transferring the mechanical energy stored in the spring into a driving force. The force is magnified by a tool disposed on the tool portion of the self-contained force magnifying hand tool and applied to a workpiece.

Abstract: The present disclosure features, at least in part, methods for conserving cell function, e.g., immune cell function, e.g., after one or more cycles of freezing and/or thawing the nucleated cell. In embodiments, the methods comprise contacting an immune cell with a protein nanoparticle comprising an IL-15 complex.

Abstract: A large lumen guide catheter (10) has an elongate tubular body (22), which has an outer surface (24), an inner surface (44), and a braided wire layer between the inner surface and the outer surface, wherein the wires winding a first helical direction are thicker and wider than the wire winding in a second helical direction opposite the first helical direction.

Abstract: A spinal implant has proximal and distal regions, and includes upper and lower bodies. A proximal adjustment assembly is disposed between the upper and lower bodies in the proximal region of the spinal implant and is adjustably coupled to the upper and lower bodies, and a distal adjustment assembly is disposed between the upper and lower bodies in the distal region of the spinal implant and is adjustably coupled to the upper and lower bodies. The proximal and distal adjustment assemblies are independently movable with respect to each other, both concurrently and alternately, to change a vertical height of at least one of the proximal or distal regions of the spinal implant. A set screw is removably disposed within the proximal region of the spinal implant to lock the vertical height of the proximal and distal regions of the spinal implant.

Abstract: Among other things, embodiments of the present disclosure may be used to help train speech recognizers for improving generalized voice experience quality in a chat bot system. In some embodiments, the system provides users with games to play to increase user engagement with the chat bot system.

Abstract: An abdominal closure method and device is disclosed where the device generally includes a first tissue securement member configured for securement to a first tissue region and a second tissue securement member configured for securement to a second tissue region. The first and second tissue securement members are coupled to the connecting member and the connecting member is positionable at a distance from the first and second tissue regions. Additionally, one or more biasing elements may be connected to the first and second tissue securement members to approximate the first and second tissue regions towards one another via respective securement members.

Abstract: A polyaxial pedicle screw includes a housing, a bone screw member, and an anvil. The bone screw member includes a head and a threaded shaft extending from the head. The head is selectively securable within the housing. The anvil is positionable within the housing adjacent to the head of the bone screw member when the anvil and the head of the bone screw member are positioned within the housing. The anvil may define one or more grooves in an outer surface of the anvil. The groove defines a flap that is flexibly attached to the anvil to enable the anvil to flex an amount sufficient to maintain the head of the bone screw in constant contact with the anvil when the bone screw member is moved relative to the anvil. A rod reducer may be secured to the polyaxial pedicle screw to secure a spinal rod within the housing.

Abstract: A hydraulic control system includes a variable displacement hydraulic pump, the pump having an inlet for receiving fluid, an outlet for discharging fluid under pressure, and a pump displacement input, a hydraulic motor having an inlet and an outlet a fluid circuit including a supply conduit for conducting fluid discharged by the pump to the motor and a return conduit for returning fluid discharged by the motor to the pump, a pump displacement control cooperating with the pump displacement input in order to vary a displacement of the pump, a control circuit in communication with the pump displacement control for controlling the pump output such that the motor is driven at a constant rotational speed and at least two valves controlling a rotational speed of the motor, wherein one of the valves provides coarser flow control resolution and another of the valves provides finer flow control resolution.

Abstract: A user interface assembly for a gaming device includes a first-side transceiver subassembly on a first side of a barrier, including a first-side antenna and a first-side transmitter circuit electronically coupled to the first-side antenna for transmitting an electromagnetic power signal through the barrier via the first-side antenna. The user interface assembly also includes a second-side transceiver subassembly on a second side of the barrier opposite the first-side transceiver subassembly, including a second-side antenna disposed opposite the first-side antenna relative to the barrier, and a second-side receiver circuit electronically coupled to the second-side antenna for receiving, via the second-side antenna, the electromagnetic power signal transmitted through the barrier.

Abstract: Among other things, embodiments of the present disclosure may be used to help train speech recognizers for improving generalized voice experience quality in a chat bot system. In some embodiments, the system provides users with games to play to increase user engagement with the chat bot system.

Abstract: A spinal implant has proximal and distal regions, and includes upper and lower bodies. A proximal adjustment assembly is disposed between the upper and lower bodies in the proximal region of the spinal implant and is adjustably coupled to the upper and lower bodies, and a distal adjustment assembly is disposed between the upper and lower bodies in the distal region of the spinal implant and is adjustably coupled to the upper and lower bodies. The proximal and distal adjustment assemblies are independently movable with respect to each other, both concurrently and alternately, to change a vertical height of at least one of the proximal or distal regions of the spinal implant. A set screw is removably disposed within the proximal region of the spinal implant to lock the vertical height of the proximal and distal regions of the spinal implant.

Abstract: A beverage container may comprise a beverage container lid assembly comprising at least one concentrate well to hold a concentrate vessel, a concentrate vessel retainer for each concentrate well to secure the concentrate vessel in the concentrate well, a feed line for each concentrate well comprising a feed line needle to puncture the concentrate vessel in the at least one concentrate well, a Venturi mixer in fluid communication with each feed line, a mixing valve in fluid communication with each feed line, wherein fluid flows from the concentrate vessel to the Venturi mixer when the mixing valve is open and the concentrate vessel is punctured by the feed line needle. Methods of using the beverage container and beverage container lid assembly are also described.

Abstract: A method for mitigating an involuntary muscle movement in a patient by applying external vibration in multiple locations distributed about a periphery of an upper arm or forearm of the patient for an applied vibration duration that is less than the efficacy duration. Applied vibration duration as a percentage of efficacy duration is ideally less than 80%. A wearable device for performing the method has a flexible base for removably affixing to a patient's upper arm or forearm, a plurality of vibration generators, a power source, and a connected microcontroller configured to control the vibration generated by the vibration generators in accordance with a pulse frequency. The microcontroller is configured to connect to a remote controller via a communications interface. The vibration generators have a nominal vibration frequency different from the pulse frequency.