Abstract: Method for purifying metal halide precursors, and related compositions, related methods, and the like. A method comprises one or more of the following steps: obtaining a metal halide precursor, the metal halide precursor comprising a metal halide compound and at least one impurity; contacting the metal halide precursor with an oxygen-containing compound in a presence of a polar oxygen-free solvent to form a reaction product in solution; and separating the reaction product from at least one of at least a portion of the at least one impurity, at least a portion of the solution, or any combination thereof. Other compositions and methods are provided herein.

Abstract: Provided are complexes useful in the conversion of chloro- and bromo-silanes to highly desired iodosilanes such as H2SiI2 and HSiI3, via a halide exchange reaction. The species which mediates this reaction is an iodide reactant comprising aluminum.

Abstract: Yttrium complexes and related methods are provided. A method for preparing a yttrium complex comprises contacting a metal alkylcyclopentadienyl compound and a yttrium trihalide compound in a non-coordinating solvent, so as to obtain a tris(alkylcyclopentadienyl)yttrium complex. A composition comprises a tris(alkylcyclopentadienyl)yttrium complex.

Abstract: Methods of the present disclosure include the development of a low temperature, solvent-assistant synthesis of aluminates, such as lithium tetraiodoaluminate (LiAlI4). The present disclosure includes methods of preparing a compound of formula (I): [M+q][Al(X)3I]q.

Abstract: The disclosure provides methodology for the synthesis of mono-alkylated cyclopentadiene structures, which can be obtained via fulvene intermediates. In one embodiment, the cyclopentadiene ring is substituted with a trialkylsilyl moiety, which enables the further reaction with certain metal halides to form metal adducts. For example, the monoalkyl cyclopentadienes substituted with a trimethylsilyl group can be reacted with TiCl4 to provide R*CpTiCl3 complexes, wherein R* is a group of the formula wherein R1 and R2 are as defined herein.

Abstract: The disclosure provides a process for preparing bis(monoalkyl-substituted cyclopentadiene) tungsten hydride compounds, for example bis(isopropylcyclo-pentadienyl) tungsten dihydride, via the corresponding magnesium compound and tungsten hexachloride, followed by treatment with a hydride reagent. Also provided is a process for preparing bis(monoalkyl-substituted cyclopentadiene) metal halide compounds. This latter aspect is achieved by reaction of the corresponding magnesium compound with a metal halide. Exemplary metals in this process include hafnium, zirconium, titanium, tantalum, niobium, tungsten, and molybdenum.

Abstract: Provided is methodology for the preparation of highly-desired iodosilanes such as H2SiI2 and HSi3, via a reaction of alkylaminosilanes with certain substituted acid iodides. In one embodiment, bis(diethylamino)silane is reacted with benzoyl iodide to provide diiodosilane.

Abstract: The disclosure provides methodology for the synthesis of mono-alkylated cyclopentadiene structures, which can be obtained via fulvene intermediates. In one embodiment, the cyclopentadiene ring is substituted with a trialkylsilyl moiety, which enables the further reaction with certain metal halides to form metal adducts. For example, the monoalkyl cyclopentadienes substituted with a trimethylsilyl group can be reacted with TiCl4 to provide R*CpTiCl3 complexes, wherein R* is a group of the formula wherein R1 and R2 are as defined herein.

Abstract: Provided is a process for the preparation of certain bisphosphonate compounds and their ester derivatives. In this process certain bisphosphonate compounds such as medronic acid is prepared via the reaction of the corresponding isopropyl esters with (i) trimethylsilylbromide or trimethylsilyl iodide, or (ii) trimethylsilyl chloride and an alkali metal iodide or bromide; followed by treatment with a liquid comprising water. The process surprisingly provides the desired compounds, despite having relatively bulky ester groups such as isopropyl on the starting material bisphosphonate ester.

Abstract: The disclosure provides an improved method for preparing monoalkylated cyclopentadiene species in high yield and selectivity. In the process, either a solution of dicyclopentadiene magnesium or a cyclopentadiene magnesium halide is reacted with an alkylating agent in the presence of a modifying agent to provide the monoalkylated product. In the process of the disclosure, only a mono-alkylated species is produced with no detectible amount of dialkylated product observed.

Abstract: The disclosure provides a process for preparing bis(monoalkyl-substituted cyclopentadiene) tungsten hydride compounds, for example bis(isopropylcyclopentadienyl)tungsten dihydride, via the corresponding magnesium compound and tungsten hexachloride, followed by treatment with a hydride reagent. Also provided is a process for preparing bis(monoalkyl-substituted cyclopentadiene) metal halide compounds. This latter aspect is achieved by reaction of the corresponding magnesium compound with a metal halide. Exemplary metals in this process include hafnium, zirconium, titanium, tantalum, niobium, tungsten, and molybdenum.

Abstract: Provided is a process for the mono-alkylation of cyclopentadiene, utilizing a cyclopentadiene magnesium halide and a metal salt of an alkyl or aryl sulfonate as co-reactant with an alkyl halide alkylating reactant. The process provides facile methodology for the mono-alkylation of cyclopentadiene, with conversions as high as about 96 percent and selectivity for mono-alkylation (over higher level alkylation, such as di- or tri-) as high as about 99%.

Abstract: The disclosure provides methodology for the synthesis of mono-alkylated cyclopentadiene structures, which can be obtained via fulvene intermediates. In one embodiment, the cyclopentadiene ring is substituted with a trialkylsilyl moiety, which enables the further reaction with certain metal halides to form metal adducts. For example, the monoalkyl cyclopentadienes substituted with a trimethylsilyl group can be reacted with TiCl4 to provide R*CpTiCl3 complexes, wherein R* is a group of the formula wherein R1 and R2 are as defined herein.

Abstract: The disclosure provides a process for preparing bis(monoalkyl-substituted cyclopentadiene) tungsten hydride compounds, for example bis(isopropylcyclopentadienyl)tungsten dihydride, via the corresponding magnesium compound and tungsten hexachloride, followed by treatment with a hydride reagent. Also provided is a process for preparing bis(monoalkyl-substituted cyclopentadiene) metal halide compounds. This latter aspect is achieved by reaction of the corresponding magnesium compound with a metal halide. Exemplary metals in this process include hafnium, zirconium, titanium, tantalum, niobium, tungsten, and molybdenum.

Abstract: The disclosure provides a facile process for preparing certain half-sandwich titanocene compounds. The compounds are useful in catalyst systems for polyolefin synthesis. In one embodiment, highly-pure trimethyl(pentamethylcyclopentadienyl)titanium (IV) is produced from the reaction of trichloro(pentamethylcyclopentadienyl)titanium (IV) with a methyl magnesium halide compound.

Abstract: Provided is a process for the mono-alkylation of cyclopentadiene, utilizing a cyclopentadiene magnesium halide and a metal salt of an alkyl or aryl sulfonate as co-reactant with an alkyl halide alkylating reactant. The process provides facile methodology for the mono-alkylation of cyclopentadiene, with conversions as high as about 96 percent and selectivity for mono-alkylation (over higher level alkylation, such as di- or tri-) as high as about 99%.

Abstract: Provided is methodology for the preparation of highly-desired iodosilanes such as H2SiI2 and HSi3, via a reaction of alkylaminosilanes with certain substituted acid iodides. In one embodiment, bis(diethylamino)silane is reacted with benzoyl iodide to provide diiodosilane.

Abstract: Provided are complexes useful in the conversion of chloro- and bromo-silanes to highly desired iodosilanes such as H2SiI2 and HSiI3, via a halide exchange reaction. The species which mediates this reaction is an iodide reactant comprising aluminum.

Abstract: A process for stereoselectively inverting a chiral center of a chemical compound is disclosed. The process first consists of forming a mixture of the chemical comopund, an enzymatic system, and a metal catalyst. Next, the process stereoselectively dehydrogenates a group attached to the chiral center with the enzymatic system in the presence of an oxidant to produce a dehydrogenated group, Lastly, the process hydrogenates the dehydrogenated group with the metal catalyst in the presence of a hydrogen source to stereoselectively invert the chiral center of the chemical compound.

Abstract: The present invention provides a catalyst system and a process for stereoselectively inverting a chiral center of a chemical compound. The catalyst system of the present invention comprises (i) a catalytic amount of a metal catalyst; (ii) an enzyme capable of oxidizing a chemical compound at a chiral center, or microorganism cells capable of producing an enzyme which is capable of oxidizing a chemical compound at a chiral center; (iii) an oxidant; and (iv) a hydrogen source. The process of the present invention comprises treating a chemical compound having a chiral center with the catalyst system of this invention.