Abstract: The present invention relates to a process to make continuous strand polymer comprising the following steps: a) providing a monomer mixture comprising water, a monomer, a crosslinker and an initiator; b) transporting the monomer mixture of step a) into a confining means wherein the monomer mixture is confined in said confining means; c) initiating polymerization of the monomer mixture in the confining means to make a continuous strand polymer; and d) emitting the continuous strand polymer from the confining means wherein the continuous strand polymer has a defined cross-sectional profile comprising an initial cross sectional diameter of at least 0.1 mm. The present invention is further directed to a process of making a continuous strand superabsorbent polymer.

Abstract: The present disclosure provides, in part, pharmaceutical compositions that comprise a spray dried dispersion which contains the disclosed compound, and optionally, pharmaceutical excipients. The pharmaceutical compositions of the disclosure may be used in the treatment of Hepatitis B (HBV).

Abstract: In accordance with the present invention there is provided a suturing device. The suturing device includes a length of suture that will be delivered to tissue and placed through the tissue adjacent an opening. The suture is advanced through the tissue surrounding the opening by needle that penetrates the tissue adjacent to the opening. A knot is then loosely tied with the length of suture and advanced to the site of the opening.

Abstract: In accordance with the present invention there is provided a suturing device. The suturing device includes a length of suture that will be delivered to the site of the PFO and placed through the tissue adjacent the opening to close the PFO. As described in greater detail below, the suture is advanced through the tissue surrounding the opening by a pair of needles that penetrate the tissue adjacent to the opening. A knot is then loosely tied with the length of suture and advanced to the site of the PFO. The tails of the suture extending from the knot are then cut and removed. It is also contemplated that a pre-formed or pre-tied knot may be disposed on the device, wherein after deployment of the suture through the tissue adjacent to the PFO and removal of the device a loop of suture having a pre-tied knot will remain, wherein the pre-tied knot may then be tightened to close the PFO. Further still it is contemplated that other means may be utilized to retain the sutures.

Abstract: In accordance with the present disclosure there is provided exemplary embodiments of an introducer sheath having a hub with an elongated tubular member extending from the hub. Disposed within the hub is a flexible valve member with a proximal surface and a distance surface and an aperture extending between the proximal surface and the distal surface. Both surfaces of the flexible valve member being parallel in a non-planar, retracted state and in a planar, relaxed state.

Abstract: In accordance with the present disclosure there is provided exemplary embodiments of an introducer sheath, wherein the introducer sheath may be formed of multiple components at least one of which may be integrally formed or resiliently assembled to form a single introducer sheath. One embodiment of the introducer sheath includes a hub and a flexible valve. The flexible valve member may be non-planar in a relaxed state.

Abstract: In accordance with the present invention there is provided a suturing device. The suturing device includes a length of suture that will be delivered to the site of the PFO and placed through the tissue adjacent the opening to close the PFO. As described in greater detail below, the suture is advanced through the tissue surrounding the opening by a pair of needles that penetrate the tissue adjacent to the opening. A knot is then loosely tied with the length of suture and advanced to the site of the PFO. The tails of the suture extending from the knot are then cut and removed. It is also contemplated that a pre-formed or pre-tied knot may be disposed on the device, wherein after deployment of the suture through the tissue adjacent to the PFO and removal of the device a loop of suture having a pre-tied knot will remain, wherein the pre-tied knot may then be tightened to close the PFO. Further still it is contemplated that other means may be utilized to retain the sutures.

Abstract: Devices and methods for securing a pair of suture lengths together or for using a single strand of suture to secure tissue(s) together at an operative site in a patient without necessarily tying a knot. The suture lock device includes a suturing securing device having an outer body member having a lumen extending therethrough. The lumen defines a suture path through the outer body. An inner wedge member is axially insertable into the outer body member to secure a portion of a suture between the wedge and the interior surface of the lock member. An outer tube has a proximal end and a distal end. The outer tube carries the outer body member at the distal end of the outer tube. The outer tube carries the wedge proximal to the outer body member.

Abstract: In accordance with the present invention there is provided exemplary embodiments of an introducer sheath in accordance with the present invention, wherein the introducer sheath of the present invention is formed of multiple components which are resiliently assembled to form a single introducer sheath. One embodiment of the introducer sheath includes a hub, a retaining member and an elongated tubular member. The hub has a lumen that has a groove. The elongated tubular member has a proximal end that includes a flared portion. The distal end of the retaining member is configured to be received in the groove formed in the lumen of the hub. The distal end of the retaining member contacts the flared portion of the tubular member when distal end of the retaining member is disposed in the groove such that the tubular member is retained within the lumen of the hub in a sealed engagement.

Abstract: In accordance with the present invention there is provided a suturing device. The suturing device includes a length of suture that will be delivered to the site of the PFO and placed through the tissue adjacent the opening to close the PFO. As described in greater detail below, the suture is advanced through the tissue surrounding the opening by a pair of needles that penetrate the tissue adjacent to the opening. A knot is then loosely tied with the length of suture and advanced to the site of the PFO. The tails of the suture extending from the knot are then cut and removed. It is also contemplated that a pre-formed or pre-tied knot may be disposed on the device, wherein after deployment of the suture through the tissue adjacent to the PFO and removal of the device a loop of suture having a pre-tied knot will remain, wherein the pre-tied knot may then be tightened to close the PFO. Further still it is contemplated that other means may be utilized to retain the sutures.

Abstract: A method for single hand operation of a hand-held band saw is provided. The band saw has a frame and a handle extending from a longitudinal edge of the frame at an acute angle and opposite an edge containing a throat for receiving the work piece, and a continuous-loop blade traversing the throat. The orientation of the handle centers the mass of the saw below the hand and positions a cutting section of the blade in a vertical plane so it will engage a work piece at a preferred angle selected by the user.

Abstract: A hand-held band saw is provided for one-hand operation. The band saw has a frame and a handle extending from a longitudinal edge of the frame at an acute angle and opposite an edge containing a throat for receiving the work piece. The orientation of the handle centers the mass of the saw below the hand and positions the cutting section of the blade in a vertical plane so it will engage a work piece at a preferred angle selected by the user.

Abstract: A method for suturing a patent foramen ovale (PFO) includes providing a suturing device, advancing the suturing device through the inferior vena cava, right atrium, and PFO such that a first foot of the device is positioned in the left atrium, deploying the first foot to a deployed position, orienting the suturing device such that a distal portion of tissue of the PFO is received in a pre-formed curve portion of a foot housing of the device, advancing the first needle through tissue and further into a first needle receptacle disposed on the first foot, and advancing at least one end of the length of suture through the tissue to suture the PFO.

Abstract: In accordance with the present invention there is provided a suturing device. The suturing device includes a length of suture that will be delivered to the site of the patent foramen ovale (PFO) and placed through the tissue adjacent the opening to close the PFO. The suture is advanced through the tissue surrounding the opening by a pair of needles that penetrate the tissue adjacent to the opening. The suture can be secured to the tissue through use of a knot, a suture clip or other clip like device to retain the suture in a position such that the PFO is closed.

Abstract: Devices and methods for securing a pair of suture lengths together or for using a single strand of suture to secure tissue(s) together at an operative site in a patient without necessarily tying a knot. The suture lock device includes a suturing securing device having an outer body member having a lumen extending therethrough. The lumen defines a suture path through the outer body. An inner wedge member is axially insertable into the outer body member to secure a portion of a suture between the wedge and the interior surface of the lock member. An outer tube has a proximal end and a distal end. The outer tube carries the outer body member at the distal end of the outer tube. The outer tube carries the wedge proximal to the outer body member.

Abstract: A suturing device includes a length of suture that will be delivered to the site of a PFO and placed through the tissue adjacent the opening to close the PFO. The suture is advanced through the tissue surrounding the opening by a pair of needles that penetrate the tissue adjacent to the opening. The suture can be secured to the tissue through use of a knot, a suture clip or other clip like device to retain the suture in a position such that the PFO is closed.

Abstract: A method and apparatus for converting a portable band saw to an upright stationary table band saw includes a stand having a base, at least one vertically extending side wall, and a top. A work piece support surface can include an opening through which one run of a closed loop saw blade of the portable band saw can pass when the portable band saw is mounted in a supporting relationship with respect to the stand. A switch mounted on the stand operates the portable band saw independent of the finger trigger on the handle. The on/off switch is connected to a plug engaged by the portable band saw when mounted in the stand. The plug is engagable within a socket of the band saw and is electrically connected to bypass the finger trigger of the portable band saw and to create a circuit through the on/off switch.

Abstract: The present invention relates to devices and methods for securing a pair of suture lengths together or for using a single strand of suture to secure tissue(s) together at an operative site in a patient without necessarily tying a knot. The suture lock device may include a suturing securing device having an outer body member having a lumen extending therethrough, the lumen defining a suture path through the outer body, an inner wedge member axially insertable into the outer body member to secure a portion of a suture between the wedge and the interior surface of the lock member, an outer tube carrying the outer body member at the distal end of the outer tube, the outer tube carrying the wedge proximal to the outer body member, and a pusher member slidable within the outer tube to push the wedge into the lock member.

Abstract: A method and apparatus for converting a portable band saw to an upright stationary table band saw includes a stand having a base, at least one vertically extending side wall, and a top. A work piece support surface can include an opening through which one run of a closed loop saw blade of the portable band saw can pass when the portable band saw is mounted in a supporting relationship with respect to the stand. A switch mounted on the stand operates the portable band saw independent of the finger trigger on the handle. The on/off switch is connected to a plug engaged by the portable band saw when mounted in the stand. The plug is engagable within a socket of the band saw and is electrically connected to bypass the finger trigger of the portable band saw and to create a circuit through the on/off switch.

Abstract: A powered hand-held band for cutting a work piece and a method for manufacture and use. The band saw includes alternate blade guides respectively for selectively using one of a first cutting path for cutting a work piece flush with respect to a work surface and a second cutting path for non-flush cuts.