Abstract: The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

Abstract: The present disclosure relates to compounds that are Syk inhibitors or pharmaceutically acceptable salts or co-crystals thereof, and pharmaceutical compositions thereof, and to their use in the treatment of various disease states, including cancer and inflammatory conditions.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for evaluating interactions with a user interface are disclosed. In one aspect, a method includes identifying a set of mutation events specifying changes to the structure of a user interface that occurred during the user session, and generating user interface states specifying different structures of the user interface throughout the given user session. Based at least in part on the user interface states, playback data that present visual changes of the user interface corresponding to the set of mutation events that occurred during the user session are generated. Session activity data describing user interactions that occurred during the user session are also generated. At least a portion of the playback data and the session activity data are output to a requesting device.

Abstract: The present system and method is directed to a process to facilitate trusted sources of information in an enterprise. The present system and method positions data governance to move away from the element level and focus on the data asset (i.e. repository, interface, subject) level. When data persons are having any issue with their data asset, whether it is a conflicting data asset, interface issues, competing data asset, new data asset build, data subject issue, or the like, a certifier may operate to assess the asset based on our well defined metrics, determine the health through the data asset scoring process, recommend asset services, and provide those services to the data owner who is ultimately responsible for implementing them to improve the data and the data processes.

Abstract: An integrated circuit system has a die with first and second sides, and contains high frequency circuitry operating at mm-wave frequencies. The system also has a plurality of interfaces (on the first side) in electrical communication with the high frequency circuitry, and a heat sink having a bottom surface with a first region and an aperture region. The first region is in physical and conductive contact with the die, while the aperture region forms a concavity with an inner concave surface that is spaced from the die.

Abstract: A detection system and method of operating the detection system are provided. The system includes a power supply unit and at least one sensor for sensing at least one of an object and a motion. A communication unit is electrically coupled to the power supply unit for communicating with a plurality of vehicle system controllers. A microprocessor is operable in a plurality of modes and electrically coupled to the power supply unit and the at least one sensor and the communication unit. The microprocessor is configured to determine which of the plurality of modes should be active based on communication with the vehicle system controllers and to receive and process the data from the at least one sensor. The microprocessor is also configured to initiate movement of the closure panel in response to processing the data corresponding to the at least one of the object and the motion.

Abstract: The present disclosure relates generally to certain ene-oxindole compounds, pharmaceutical compositions comprising thereof. Also disclosed are methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

Abstract: A deployable applique assembly for a motor vehicle is provided. The assembly includes a housing having a wall with at least one through opening extending through the wall and a panel configured to overlie at least a portion of the wall when in a stowed position, with an outer surface of the panel being configured to form a smooth surface with a body panel of the motor vehicle. The assembly includes a drive link extending through the at least one through opening and having a first end operatively coupled to the inner surface of the panel and a second end. An actuator has a drive member operably coupled with the second end of the drive link, wherein the actuator is operable to selectively pivot the drive link to move the panel between the stowed position and a deployed position.

Abstract: Certain imidazopyridines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for evaluating interactions with a user interface are disclosed. In one aspect, a method includes identifying a set of mutation events specifying changes to the structure of a user interface that occurred during the user session, and generating user interface states specifying different structures of the user interface throughout the given user session. Based at least in part on the user interface states, playback data that present visual changes of the user interface corresponding to the set of mutation events that occurred during the user session are generated. Session activity data describing user interactions that occurred during the user session are also generated. At least a portion of the playback data and the session activity data are output to a requesting device.

Abstract: An integrated circuit system has a die with first and second sides, and contains high frequency circuitry operating at mm-wave frequencies. The system also has a plurality of interfaces (on the first side) in electrical communication with the high frequency circuitry, and a heat sink having a bottom surface with a first region and an aperture region. The first region is in physical and conductive contact with the die, while the aperture region forms a concavity with an inner concave surface that is spaced from the die.

Abstract: The present disclosure relates to compounds that are Syk inhibitors or pharmaceutically acceptable salts or co-crystals thereof, and pharmaceutical compositions thereof, and to their use in the treatment of various disease states, including cancer and inflammatory conditions.

Abstract: The present system and method is directed to a process to facilitate trusted sources of information in an enterprise. The present system and method positions data governance to move away from the element level and focus on the data asset (i.e. repository, interface, subject) level. When data persons are having any issue with their data asset, whether it is a conflicting data asset, interface issues, competing data asset, new data asset build, data subject issue, or the like, a certifier may operate to assess the asset based on our well defined metrics, determine the health through the data asset scoring process, recommend asset services, and provide those services to the data owner who is ultimately responsible for implementing them to improve the data and the data processes.

Abstract: System and methods may facilitate user guidance to risk relationship documents for an enterprise. A risk relationship document data store may contain a set of electronic data records, each electronic data record being associated with a risk relationship document and including a document identifier and a set of document metadata values. A document navigation computer may receive information from a user associated with the enterprise, and, based on the information received from the user and document metadata values, dynamically create a sub-set of the documents in the risk relationship data document data store. An interactive user interface display computer may provide indications associated with the documents in the dynamically created sub-set to the user via an interactive user interface and receive a selected document of the dynamically created sub-set. The user interface display computer may then, responsive to the selection, deliver the selected document to a remote user device.

Abstract: A sign or other marking that is illuminated by an LED lamp, e.g., in a vehicle headlamp is described. The sign employs spectral shifting to increase the power or energy reflected by the sign when illuminated by the LED lamp, which has a significant power peak in the blue spectrum. The spectral shifting can be done in a conversion layer on top of a reflective layer. The reflective layer can include quantum dots to increase its efficiency in reflecting light.

Abstract: A system for disambiguation of noisy text includes an interface and processor. The interface is configured to receive a set of words. The processor is configured to determine a token from the set of words, wherein the token includes a subset of the set of words; determine candidates for the token; determine a ranking for the candidates based at least in part on a semantic similarity between the token and each of the candidates; determine whether to select a top ranked candidate or to abstain; and in response to a select determination to select the top ranked candidate, indicate the top ranked candidate is selected.

Abstract: A latch assembly for driving a closure panel from a closed panel position to an open panel position.

Abstract: Described are methods and systems to identify unauthorized attempts to access an account in a computer system, the account having an authorized user. The methods and systems include determining that a count of failed attempts to access the account exceeds a maximum. Based on the count exceeding the maximum, one or more peer contacts associated with the authorized user are retrieved from stored user data. A failure attribution request is transmitted to the one or more peer contacts and a response is received from at least one of the one or more peer contacts. If the response denies that the authorized user caused the failed attempts, then a security action is taken with respect to the account. The method may include first confirming that the number of failure attributions requests sent has not exceeded an abuse threshold to prevent denial-of-service attacks.

Abstract: Method for placing a spacecraft into a lunar orbit, either by standard (i.e., impulsive) or ballistic (i.e., non-impulsive) capture, from an Earth orbit that is significantly inclined relative to the lunar orbit plane, with no constraint on the local time of perigee for the starting orbit.

Abstract: A closure panel latch assembly can include an overslam bumper mechanism comprising a biasing element as a spring formed from a metallic material positioned relative to a slot of the latch assembly. The biasing element resists entry of a striker into the slot beyond a selected position in order to inhibit contact of the striker with a bottom end of the slot. Also provided is a closure panel latch assembly configured with the biasing element as a resilient element positioned relative to the slot of the latch assembly; The biasing element is coupled to the striker engagement member, such that the striker engagement member is positioned to engage the striker and resist travel of the striker towards the bottom end, wherein the biasing element controls the resistance to movement of the striker engagement member by the striker.