Patents by Inventor Scott A. Mitchell

Scott A. Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MECHANICAL ASSIST MECHANISM FOR ACTIVE PEDESTRIAN SAFETY LATCH
    Publication number: 20160130842
    Abstract: A latch assembly for driving a closure panel from a closed panel position to an open panel position.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 12, 2016
    Inventors: James J. Ferri, J.R. Scott Mitchell, Csaba Szente, Jagdeep Playia, Dikran Ghorghorian, John Clark, Gabriele Wayne Sabatini, Traian Miu, Aleksandar Jovanovic
  • TANK-BINDING KINASE INHIBITOR COMPOUNDS
    Publication number: 20160096827
    Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:
    Type: Application
    Filed: September 23, 2015
    Publication date: April 7, 2016
    Applicant: Gilead Sciences, Inc.
    Inventors: Zhimin Du, Juan A. Guerrero, Joshua A. Kaplan, John E. Knox, JR., Jennifer R. Lo, Scott A. Mitchell, Devan Naduthambi, Barton W. Phillips, Chandrasekar Venkataramani, Peiyuan Wang, William J. Watkins, Zhongdong Zhao
  • Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
    Patent number: 9290505
    Abstract: The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R1, R2, R3, and R4 are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts or co-crystals thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: March 22, 2016
    Assignee: Gilead Sciences, Inc.
    Inventors: Peter A. Blomgren, Kevin S. Currie, Jeffrey E. Kropf, Seung H. Lee, Jennifer R. Lo, Scott A. Mitchell, Aaron C. Schmitt, Jin-Ming Xiong, Jianjun Xu, Zhongdong Zhao, Sundaramoorthi Swaminathan
  • MODULAR HYBRID SYSTEM
    Publication number: 20160075224
    Abstract: An electric propulsion system for use with a vehicle including a pair of first wheels, a pair of second wheels, and a gas propulsion system. The electric propulsion system includes a first electric traction motor mounted to one of the first wheels, and a second electric traction motor mounted to the other one of the first wheels. The electric propulsion system includes pair of electric motor controllers each in electrical communication with a respective one of the first or second electric traction motors. Each of the electric motor controllers are also in electrical communication with the system controller and configured to receive vehicle signals from the system controller to control the respective electric traction motors accordingly. Put another way, the pair of electric motor controllers react to vehicle conditions to provide vehicle assist power to the gas propulsion system as needed.
    Type: Application
    Filed: September 14, 2015
    Publication date: March 17, 2016
    Inventors: TRAIAN MIU, J.R. SCOTT MITCHELL, GABRIELE WAYNE SABATINI, MARLON D.R. HILLA, SAMUEL R. BARUCO
  • SINGLE STAGE LEADSCREW CINCH ACTUATOR
    Publication number: 20160060922
    Abstract: A door latch assembly for an automotive vehicle door includes a gearless cinch actuator. The cinch actuator includes an extensible housing member connected to a threaded rod by a nut. The extensible housing member is also connected to a cable for cinching the door. A motor rotates the threaded rod, which moves the extensible housing member between rest and cinched positions. The motor is connected to the threaded rod without the use of gears. An anti-friction agent, such as a combination of a PTFE-containing coating and PTFE-containing grease, is applied between the nut and the threaded rod. The materials and anti-friction agent used at the interface of the threaded rod and nut together provide a friction coefficient (?) of about 0.045 or less.
    Type: Application
    Filed: September 1, 2015
    Publication date: March 3, 2016
    Inventors: John Edward CLARK, Ilya NEYMAN, Dani ANDRAOS, John Robert Scott MITCHELL, John DISTEFANO, Shant PAILIAN
  • SYK INHIBITORS
    Publication number: 20160058758
    Abstract: The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R1, R2, R3, and R4 are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk. In certain embodiments, also disclosed are methods for treating a cancer in a subject (e.g., a human) in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof, in combination with a vinca-alkaloid, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 9, 2015
    Publication date: March 3, 2016
    Inventors: Peter A. Blomgren, Astrid Clarke, Kevin S. Currie, Julie Di Paolo, Jeffrey E. Kropf, Seung H. Lee, Jennifer R. Lo, Scott A. Mitchell, Aaron C. Schmitt, Sundaramoorthi Swaminathan, Jin-Ming Xiong, Jianjun Xu, Zhongdong Zhao
  • ROUTE EXAMINING SYSTEM AND METHOD
    Publication number: 20160054250
    Abstract: A system may include a coded test signal transmission system configured to transmit a unique coded test signal along a route, and a coded test signal receiving system configured to receive the unique coded test signal along the route. The unique coded test signal received by the coded test signal receiving system is used to determine one or more characteristics of the route.
    Type: Application
    Filed: August 20, 2014
    Publication date: February 25, 2016
    Inventors: Ajith Kuttannair Kumar, Jeffrey Michael Fries, Joseph Forrest Noffsinger, Michael Scott Mitchell, Steven Joseph Ehret
  • IMIDAZOPYRAZINE SYK INHIBITORS
    Publication number: 20160031894
    Abstract: Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
    Type: Application
    Filed: October 13, 2015
    Publication date: February 4, 2016
    Inventors: Scott A. Mitchell, Kevin S. Currie, Peter A. Blomgren, Jeffrey E. Kropf, Seung H. Lee, Jianjun Xu, Douglas G. Stafford, James P. Harding, Antonio J.M. Barbosa, JR., Zhongdong Zhao, David M. Armistead, Soumya Mitra
  • COMPONENTS FOR ACTIVE PEDESTRIAN SAFETY MECHANISM
    Publication number: 20160023630
    Abstract: A latch assembly for driving a closure panel from a closed panel position to an open panel position.
    Type: Application
    Filed: October 8, 2015
    Publication date: January 28, 2016
    Inventors: James J. Ferri, John Robert Scott Mitchell, Csaba Szente, Jagdeep Playia, Dikran Ghorghorian, Gabriele Wayne Sabatini, Traian Miu, John Clark
  • Powered garage door opener
    Patent number: 9234377
    Abstract: A powered garage door opener is provided for operating a garage door between an open and closed position. The powered garage door opener comprises a main housing mounted adjacent the garage door. An electric motor and gear train assembly is mounted within the main housing and coupled to the garage door to drive the garage door between the open and closed positions. A power supply is mounted within the main housing and electrically connected to the electric motor and gear train assembly. A control module is mounted within the main housing and electrically connected to the power supply and the electric motor and gear train assembly for controlling selective actuation of the electric motor and gear train assembly.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: January 12, 2016
    Assignee: Magna Closures Inc.
    Inventors: Kurt Schatz, J.R. Scott Mitchell
  • 6-(2,3-dihydro-1H-pyrido-[2,3-b][1,4]oxazin-7-yl)-N-(4-morpholinophenyl)imidazo[1,2-a] pyrazin-8-amine as a spleen tyrosine kinase inhibitor
    Patent number: 9212191
    Abstract: Provided are imidazopyrazine compounds, particularly including 6-(2,3-dihydro-1H-pyrido-[2,3-b][1,4]oxazin-7-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazine-8-amine, structure below, and methods and formulations for their use in inhibiting Spleen Tyrosine Kinase in treating conditions including B-cell lymphomas or leukemias and inflammatory conditions:
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: December 15, 2015
    Assignee: GILEAD CONNECTICUT, INC.
    Inventors: Scott A. Mitchell, Kevin S. Currie
  • Components for active pedestrian safety mechanism
    Patent number: 9156432
    Abstract: A latch assembly for driving a closure panel from a closed panel position to an open panel position.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: October 13, 2015
    Assignee: Magna Closures Inc.
    Inventors: James J. Ferri, John Robert Scott Mitchell, Csaba Szente, Jagdeep Playia, Dikran Ghorghorian, Gabriele Wayne Sabatini, Traian Miu, John Clark
  • 6-(1-indazol-6-YL)--(4-morpholinophenyl)imidazo[1,4-A]pyrazin-8-amine for treating leukemia or lymphoma
    Patent number: 9120811
    Abstract: Provided are imidazopyrazine compounds, including 6-(1H-indazol-6-yl)-N-(4 -moirpholinophenyl)imidazo-[1,2-a]pyrazine-8-amine: and methods for using the imidazopyrazine compounds for treating diseases and disorders responsive to the inhibition of Syk activity, including leukemia and lymphoma.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: September 1, 2015
    Assignee: Gilead Connecticut, Inc.
    Inventors: Scott A. Mitchell, Kevin S. Currie
  • SYK INHIBITORS
    Publication number: 20150175616
    Abstract: The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R1, R2, R3, and R4 are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts or co-crystals thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.
    Type: Application
    Filed: December 22, 2014
    Publication date: June 25, 2015
    Inventors: Peter A. Blomgren, Kevin S. Currie, Jeffrey E. Kropf, Seung H. Lee, Jennifer R. Lo, Scott A. Mitchell, Aaron C. Schmitt, Jin-Ming Xiong, Jianjun Xu, Zhongdong Zhao
  • Complex event processing system having multiple redundant event processing engines
    Patent number: 9009234
    Abstract: A system and method for replicating a distributed computer system state among a plurality of deterministic event processing engines are disclosed. A sender module receives a plurality of input events or input event streams and generates a serialized message sequence describing an order in which input events are processed. The serialized message sequence is then transmitted to a plurality of deterministic event processing engines for processing. As the event processing engines are deterministic, each event processing engine produces the same ordered sequence responsive to the received serialized message sequence. The ordered sequences from each deterministic event processing engine are transmitted to a merger module which generates an output from the plurality of ordered sequences. The merger module removes one or more redundant ordered sequences and associates the resulting output with a client device.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: April 14, 2015
    Assignee: Software AG
    Inventors: Robert Scott Mitchell, Mark K. Horsburgh, Richard M. Bentley
  • OVERSLAM BUMPER FOR VEHICLE DOOR LATCH
    Publication number: 20150076835
    Abstract: A closure panel latch assembly can include an overslam bumper mechanism comprising a biasing element as a spring formed from a metallic material positioned relative to a slot of the latch assembly. The biasing element resists entry of a striker into the slot beyond a selected position in order to inhibit contact of the striker with a bottom end of the slot. Also provided is a closure panel latch assembly configured with the biasing element as a resilient element positioned relative to the slot of the latch assembly; The biasing element is coupled to the striker engagement member, such that the striker engagement member is positioned to engage the striker and resist travel of the striker towards the bottom end, wherein the biasing element controls the resistance to movement of the striker engagement member by the striker.
    Type: Application
    Filed: August 13, 2014
    Publication date: March 19, 2015
    Inventors: John Robert Scott Mitchell, Ioan Dorin Ilea, James Joseph Ferri
  • POWER DOOR ACTUATION SYSTEM
    Publication number: 20150059250
    Abstract: A power door actuation system for moving a vehicle door relative to a vehicle body between an open position and a closed position includes a motor assembly connectable to one of the vehicle door and the vehicle body that is configured to generate a rotational force. A drive shaft is interconnected to the motor assembly and extends from a first end disposed adjacent the motor assembly to a second end. The second end of the drive shaft is rigidly attached to one of a body strap or a door strap of a hinge for transferring the rotational force from the motor assembly to the respective rigidly attached strap to rotate the respective rigidly attached strap relative to the other of the door strap and the body strap for automatically moving the vehicle door between the open and closed positions.
    Type: Application
    Filed: August 29, 2014
    Publication date: March 5, 2015
    Inventors: Traian Miu, J. R. Scott Mitchell, Gabriele Wayne Sabatini
  • Imidazopyrazine Syk inhibitors
    Patent number: 8962835
    Abstract: Certain imidazopyrazines of Formula (I): or pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: February 24, 2015
    Assignee: Gilead Connecticut, Inc.
    Inventors: Scott A. Mitchell, Kevin S. Currie, Peter A. Blomgren, Jeffrey E. Kropf, Seung H. Lee, Jianjun Xu, Douglas G. Stafford
  • HOCKEY SKATE SHIELD
    Publication number: 20150028576
    Abstract: A skate shield for use with ice skates. The skate shield includes a rigid shell made at least of outer and inner layers of fiber reinforced plastic or polymer (FRP), and a fastener assembly for releasably securing the shell to a boot portion of the ice skate. The shell includes a medial side portion interconnected to a lateral side section via a top portion. A reinforced section formed by reinforcing layers laminated between the outer and inner layers is provided in at least one of the medial side portion and the lateral side portion of the shell.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 29, 2015
    Inventors: Kurt Schatz, J. R. Scott Mitchell, Michael Smart
  • POWERED GARAGE DOOR OPENER
    Publication number: 20150007500
    Abstract: A powered garage door opener is provided for operating a garage door between an open and closed position. The powered garage door opener comprises a main housing mounted adjacent the garage door. An electric motor and gear train assembly is mounted within the main housing and coupled to the garage door to drive the garage door between the open and closed positions. A power supply is mounted within the main housing and electrically connected to the electric motor and gear train assembly. A control module is mounted within the main housing and electrically connected to the power supply and the electric motor and gear train assembly for controlling selective actuation of the electric motor and gear train assembly.
    Type: Application
    Filed: June 20, 2014
    Publication date: January 8, 2015
    Inventors: Kurt Schatz, J.R. Scott Mitchell