Abstract: A privacy enabled system for managing clinical study participant travel has a database (stores data: clinical study, participant, clinical site and trip data sets) and a graphical user interface that has a Travel Planning Interface and is in data communication with an input device and the database. The data sets include a Study Travel Policy, a Study Visit Schedule (appointment procedure, appointment schedule), a traveler profile, traveler personal data (traveler contact information), a site appointment location associated with the appointment procedure, and site contact information. The travel planning interface receives the trip data set (trip segment data) from the database and the input device. The travel planning interface transmits the trip segment data to and receives booked travel data from a travel booking module, generates an itinerary that has booked travel and trip segment data, and transmits the itinerary according to the traveler contact information and the site contact information.

Abstract: Systems for visualization and management of a travel policy for a clinical study have a study dataset having a first travel policy condition, a study travel policy dataset having a main travel policy and a specialized travel policy, and a GUI having a travel policies interface and a travel policy control. The first travel policy condition may be a country, a clinical site, a traveler policy label, a visit attribute, a visit policy label, and combinations thereof. The specialized travel policy (a country policy, a site policy, a first visit policy, a second visit policy, a custom policy, and combinations thereof) is programmatically associated with the first travel policy condition.

Abstract: Mobile management method, system and client. Method includes receiving a DNS query for a host name from an application on client; retrieving reputation data associated with host name from a local cache on client; and determining a policy based on host name and the reputation data. Based on determined policy for the host name, blocking attempted network flows to a host corresponding to host name to produce blocked attempted network flows. Method also includes sending attempted network flow metadata related to the blocked attempted network flows to a collector on client; transmitting the attempted network flow metadata from the collector to a VPN server pool via a VPN tunnel; and producing an anomaly report from the transmitted attempted network flow metadata. The anomaly report includes at least one of anomalies, cohorts, trends, location boundaries, detected network security issues, detected compromised clients and/or optimized network usage.

Abstract: A proppant container facilitates the transportation of wet sand for use in a hydraulic fracturing operation. The container is mounted in a cradle that tips downward in arcuate motion for discharge or proppant through a top opening The tipping mechanism may be driven by a system of gears or a hydraulic ram.

Abstract: A method includes determining, by a sensor node in communication with a communication network, an evacuation condition, retrieving by a decision node, occupancy information pertaining to an area, retrieving area data, and determining an evacuation route, at least in part using the evacuation condition, occupancy information, and area data, and communicating the determined evacuation route to area occupants.

Abstract: Catheter devices can have bendable extension legs. The extension legs may be designed to include armature wire that enables the extension legs to be bent into and to retain a variety of orientations. As a result, a clinician can easily position the luers of the extension legs into positions that are suitable for a particular patient and/or the clinician.

Abstract: The present disclosure provides methods of preparing heteroaryl-containing compounds, wherein an azide-alkyne cycloaddition is accelerated in the presence of lauryldimethylamine oxide (LDAO). The present disclosure further provides conjugates of polypeptides and antigens prepared using such methods.

Abstract: Systems and methods for a tightly coupled trajectory predictor with constant up-finding are provided. In certain embodiments, a system includes an inertial measurement unit that provides inertial measurements of a vehicle. The system also includes an up-finding sensor that provides up-finding measurements based on when a portion of the vehicle is pointing up. Further, the system includes one or more processors that bound errors from the inertial measurements in a navigation solution during navigation of the vehicle using the up-finding measurements.

Abstract: Recovery time and/or airflow of flexible polyurethane foam is increased by including certain tackifiers in the foam formulation. The tackifiers are characterized in being incompatible with polyol or polyol mixture used to make the foam, having a viscosity of at least 10,000 centipoise at 25° C., having a glass transition temperature of at most 15° C. and being inert to other components of the foam formulation.

Abstract: A slider for a zipper closure includes a separator plow that is positionable between interlocking tracks of the zipper closure to open the zipper closure by pivoting an opening end of the slider in a direction toward a notch to position the plow between the interlocking closures. The slider can be disengaged by pivoting the slider so that the plow is outside of the interlocking tracks.

Abstract: Solutions and methods are disclosed for the extraction and quantification of cellulose derived from cellulosic biomass samples. Improved extraction yields and selectivities are provided through the use of an extraction solvent mixture comprising an aprotic solvent such as DMSO, a quaternary ammonium salt such as TBAF, and an quaternary ammonium base such as TBAOH. The extracted cellulose can be optionally precipitated using disclosed precipitation solutions to further improve cellulose purity. Extracted cellulose can be measured by hydrolyzing the cellulose to glucose or cellobiose, or by using disclosed spectrophotometric assays of cellulose-salt complexes.

Abstract: Solutions and methods are disclosed for the extraction and quantification of cellulose derived from cellulosic biomass samples. Improved extraction yields and selectivities are provided through the use of an extraction solvent mixture comprising an aprotic solvent such as DMSO, a quaternary ammonium salt such as TBAF, and an quaternary ammonium base such as TBAOH. The extracted cellulose can be optionally precipitated using disclosed precipitation solutions to further improve cellulose purity. Extracted cellulose can be measured by hydrolyzing the cellulose to glucose or cellobiose, or by using disclosed spectrophotometric assays of cellulose-salt complexes.

Abstract: Recovery time and/or airflow of flexible polyurethane foam is increased by including certain tackifiers in the foam formulation. The tackifiers are characterized in being incompatible with polyol or polyol mixture used to make the foam, having a viscosity of at least 10,000 centipoise at 25° C., having a glass transition temperature of at most 15° C. and being inert to other components of the foam formulation.

Abstract: The present disclosure pertains to a mechanical ventilator system configured to control a pressurized flow of breathable gas for delivery to a subject based on alveolar ventilation of the subject. The mechanical ventilator system comprises a pressure generator configured to generate the pressurized flow of breathable gas for delivery to the subject, the pressure generator configured to control one or more ventilation parameters of the pressurized flow of breathable gas according to a prescribed mechanical ventilation therapy regime; one or more sensors configured to generate output signals conveying information related to the alveolar ventilation of the subject; and one or more hardware processors configured by machine-readable instructions to: determine the alveolar ventilation of the subject based on the output signals; and cause the pressure generator to adjust the one or more ventilation parameters of the pressurized flow of breathable gas based on the determined alveolar ventilation.

Abstract: A slider for a zipper closure includes a separator plow that is positionable between interlocking tracks of the zipper closure to open the zipper closure by pivoting an opening end of the slider in a direction toward a notch to position the plow between the interlocking closures. The slider can be disengaged by pivoting the slider so that the plow is outside of the interlocking tracks.

Abstract: A noise mitigation boot that can be installed on or integrated into a miniature diaphragm pump to reduce the overall noise and improve sound quality during operation. The diaphragm pump includes a housing having first and second ports and an interior chamber, a pumping diaphragm disposed in the interior chamber and dividing the interior chamber into a pumping chamber and a backside chamber, a motor for reciprocating the pumping diaphragm for pumping air into and out of the pumping chamber, and flow passages connecting the pumping chamber to the first and second ports. The first port is configured for attachment to a flow line and the second port opens to an exterior surface of the housing. The noise mitigation boot has a muffler wall overlying the exterior surface of the housing. The muffler wall has formed therein a passage extending from the second port to the backside chamber for effecting fluid communication between the second port and the backside chamber.

Abstract: A slider for a zipper closure includes a separator plow that is positionable between interlocking tracks of the zipper closure to open the zipper closure by pivoting an opening end of the slider in a direction toward a notch to position the plow between the interlocking closures. The slider can be disengaged by pivoting the slider so that the plow is outside of the interlocking tracks.

Abstract: A slider for a zipper closure includes a separator plow that is positionable between interlocking tracks of the zipper closure to open the zipper closure by pivoting an opening end of the slider in a direction toward a notch to position the plow between the interlocking closures. The slider can be disengaged by pivoting the slider so that the plow is outside of the interlocking tracks.

Abstract: The present disclosure pertains to a mechanical ventilator system configured to control a pressurized flow of breathable gas for delivery to a subject based on alveolar ventilation of the subject. The mechanical ventilator system comprises a pressure generator configured to generate the pressurized flow of breathable gas for delivery to the subject, the pressure generator configured to control one or more ventilation parameters of the pressurized flow of breathable gas according to a prescribed mechanical ventilation therapy regime; one or more sensors configured to generate output signals conveying information related to the alveolar ventilation of the subject; and one or more hardware processors configured by machine-readable instructions to: determine the alveolar ventilation of the subject based on the output signals; and cause the pressure generator to adjust the one or more ventilation parameters of the pressurized flow of breathable gas based on the determined alveolar ventilation.

Abstract: An Inertial Navigation System (INS) testing system includes a Unit Under Test (UUT) with an INS module, a DAT tool configured to provide command and control functions to a user, and a Dynamically Integrated Navigation Tester (DINT) in communication with the UUT and the DAT tool. The DINT includes a truth data conversion module configured to receive truth data and convert it to navigation data suitable for transmission to the UUT. The INS testing system advantageously allow a user to interface with a UUT while providing user-specified dynamic inputs from the DINT with the truth data selected by the user.