Abstract: An awning keder includes an awning bead extending along a length of the keder that is sized for insertion into a keder rail, and a connecting panel coupled with the awning bead and extending along the length of the keder. The awning bead and the connecting panel are integrated into a one-piece keder. The one-piece component does not require additional assembly or alteration before welding onto a vinyl canopy, thereby cutting down on production time. The keder is also more durable and less susceptible to expansion or shrinkage resulting from environmental changes.

Abstract: An awning keder includes an awning bead extending along a length of the keder that is sized for insertion into a keder rail, and a connecting panel coupled with the awning bead and extending along the length of the keder. The awning bead and the connecting panel are integrated into a one-piece keder. The one-piece component does not require additional assembly or alteration before welding onto a vinyl canopy, thereby cutting down on production time. The keder is also more durable and less susceptible to expansion or shrinkage resulting from environmental changes.

Abstract: An awning shield connector connects an awning shield to a structure. The awning shield connector includes an elongated strip of PVC material with a first bead along one side of the elongated strip and shaped to engage an awning rail on the structure, and a second bead along an opposite side of the elongated strip and shaped to engage the awning shield. A third bead for a light strip or the like is positioned between the first and second beads and extends along a length of the elongated strip.

Abstract: Peptide compositions which inhibit the binding of one protein to another protein, and corresponding methods of use are disclosed. These peptide compositions include at least one peptide which binds to one protein, and at least one peptide which binds to the other protein. In the preferred embodiment, the peptide composition is composed of a combination of cyclic ICAM-1-based and LFA-1-based peptides which inhibit the binding of LFA-1 to ICAM-1. Such LFA-1/ICAM-1-based peptide compositions can be used to treat disease states such as rejection of transplanted organs, allergies, and autoimmune diseases.

Abstract: Methods and compositions useful in inhibiting integrin-associated diseases are provided. The compositions contain a polypeptide having one or more D-amino acids that inhibit integrin binding to its associated binding polypeptide. The compositions include retro-inverso polypeptides.

Abstract: Peptide compositions which inhibit the binding of one protein to another protein, and corresponding methods of use are disclosed. These peptide compositions include at least one peptide which binds to one protein, and at least one peptide which binds to the other protein. In the preferred embodiment, the peptide composition is composed of a combination of cyclic ICAM-1-based and LFA-1-based peptides which inhibit the binding of LFA-1 to ICAM-1. Such LFA-1/ICAM-1-based peptide compositions can be used to treat disease states such as rejection of transplanted organs, allergies, and autoimmune diseases.

Abstract: Short-chain peptides replicating fragments of functional domains derived from LFA-1 and ICAM-1 parent protein sequences serve to modulate the ICAM/LFA binding interaction. In one aspect of the invention, this modulation serves to block interprotein binding reactivity, as a peptide of the invention binds to a target protein in a manner that precludes the normal binding reaction between ICAM-1 and LFA-1. In another aspect of the invention, this modulation enhances the reactivity of a first peptide, as a second peptide induces a conformational change in the target protein from a first conformation to a second, more reactive, conformation. The peptides are used according to a method including the steps of providing the proteins and applying them to a population of cells.

Abstract: Short-chain peptides replicating fragments of functional domains derived from LFA-1 and ICAM-1 parent protein sequences serve to modulate the ICAM/LFA binding interaction. In one aspect of the invention, this modulation serves to block interprotein binding reactivity, as a peptide of the invention binds to a target protein in a manner that precludes the normal binding reaction between ICAM-1 and LFA-1. In another aspect of the invention, this modulation enhances the reactivity of a first peptide, as a second peptide induces a conformational change in the target protein from a first conformation to a second, more reactive, conformation. The peptides are used according to a method including the steps of providing the proteins and applying them to a population of cells.