Abstract: A liquid dispensing system for dispensing two or more liquids of different composition, viscosity, solubility and/or miscibility at high filling speeds into a container through a unitary dispensing nozzle to improve homogeneous mixing of such liquids, while said nozzle is an integral piece free of any movable parts.

Abstract: A flexible packaging laminate has built-in opening/reclose and tamper-evidence features by forming the laminate from an outer structure joined in face-to-face relation to an inner structure. Score lines are formed in both structures to enable an opening to be formed through the laminate by lifting a flap or the like out of the plane of the laminate. The score line through the outer structure defines a larger opening than the score line through the inner structure, such that a marginal region of the outer structure extends beyond the edge of the opening portion of the inner structure. A pressure-sensitive adhesive is used to re-adhere the marginal region to an underlying surface of the inner structure adjacent the opening through the laminate. The outer score line includes at least one tear portion that is torn through upon initial opening, thus indicating the package has been at least partially opened.

Abstract: A compound having the following formula is disclosed. The compound is useful as an emitter in OLED applications.

Abstract: An environmentally friendly insulated packing system is provided. The insulated packing system may include a base layer and an insulating layer disposed on the base layer in one or more areas. The insulating layer may be a plurality of block-shaped pockets having a substantially rectangular or cube form in each of the one or more areas. The base layer may be folded to join the substantially rectangular forms and align with the inner surface of all or part of a shipping container, e.g., a box. In an alternate embodiment, the insulating packing system may be in the form of a bag/pliable box.

Abstract: The invention relates to imidazopyridines of Formula (I) and pharmaceutically acceptable salts thereof, wherein R0 to R5 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.

Abstract: This document describes a single-layer air waveguide antenna integrated on a circuit board. The waveguide guides electromagnetic energy through channels filled with air. It is formed from a single layer of material, such as a sheet of metal, metal-coated plastic, or other material with conductive surfaces that is attached to a circuit board. A portion of a surface of the circuit board is configured as a floor of the channels filled with air. This floor is an electrical interface between the circuit board and the channels filled with air. The single layer of material is positioned atop this electrical interface to define walls and a ceiling of the channels filled with air. The single layer of material can be secured to the circuit board in various ways. The cost of integrating an air waveguide antenna on to a circuit board this way may be less expensive than other waveguide-manufacturing techniques.

Abstract: The present disclosure describes ultrasound imaging systems and methods for ultrasonically inspecting biological tissue. An ultrasound imaging system according to the present disclosure may be configured to automatically apply tissue-specific imaging parameter settings (312, 314) based upon the automatic identification of the type of tissue being scanned. Tissue type identification (315) may be performed automatically for the images in the live image stream (304) and thus adjustments to the imaging settings may be applied automatically by using a neural network (320) and thus dynamically during the exam obviating the need for the sonographer to manually switch presets or adjust the imaging settings when moving to different portion of the anatomy.

Abstract: A compound having the structures: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or pharmaceutically acceptable salt, wherein; R selected from the group consisting of H, C1-C6 alkyl, C1-C6 alkoxy and —(CH2)m—W, where W is C3-C8 cycloalkyl, bicycloalkyl, bridged bicycloalkyl, phenyl, 5- or 6-membered heteroaryl or heterocyclic containing one, two or three heteroatoms selected from the group consisting of N, S and O atoms; wherein each of said alkyl, cycloalkyl, alkoxy, heterocyclic, phenyl, naphthyl or heteroaryl may be unsubstituted or substituted by phenyl, halo, cyano, deuterium, hydroxy, C1-C6 alkyl, C1-C6 alkoxy, —SO2—R?, —CONR?R?, NR?COR?, —NR?CONR?R?, —NR?CO2R?, —(CH2)n—SO2—R?, —NHSO2—R?, —NR?SO2—R?, —SO2NR?R?, NR?R? or SR? where R? and R? are independently H, C1-C6 alkyl or C3-C8 cycloalkyl; R1 selected from the group consisting of phenyl, naphthyl, 5- or 6-membered heteroaryl or heterocyclic containing one, two, three or four heteroatoms se

Abstract: A system may provide a plurality of communication modes to a remote server system and provide remote control and monitoring of the system via two-way communication. The system may communicate with an alarm processor of an alarm system. The system may determine a communication mode to provide communication between the alarm system and the remote server. The system may send status and alarm conditions to the remote server, and the system may send control signals to the alarm system. The remote server may provide a pre-determined response to information received from the alarm system, for example the alarm system may provide alarm system condition information to a user or a monitoring station for response.

Abstract: A passive circuit component includes an edge having a low line edge roughness (LER). A method for manufacturing the passive circuit component includes a self-aligned double patterning (SADP) etch process using a tri-layer process flow. The tri-layer process flow includes use of an underlayer, hard mask, and photoresist. The passive circuit component made by this method achieves improved mismatch between like components due to the low LER.

Abstract: The present disclosure relates to compounds of Formula (Ia) and (Ib): or a pharmaceutically acceptable salt thereof, which are useful in the treatment of an HIV infection in heavily treatment-experienced patients with multidrug resistant HIV infection.

Abstract: A needle bending assembly configured to at least temporarily contain a needle can include a first housing section, a second housing section, and a coupling element coupled between the first housing section and the second housing section. The first housing section defines a first cavity configured to at least temporarily contain a first section of the needle. The second housing section defines a second cavity configured to at least temporarily contain a second section of the needle forming a distal tip. The coupling element is configured such that when the needle is contained within the housing sections, movement of the second housing section relative to the first housing section results in a bending of the needle at a location corresponding to the coupling element.

Abstract: A Heating, Ventilation, and Air Conditioning (HVAC) system that is configured to receive a refrigerant from a condenser at a fixed expansion device and a variable expansion device. The system is further configured to output a first portion of the refrigerant to a first downstream HVAC component at a fixed flow rate using the fixed expansion device. The system is further configured to apply a first force to a pin of the variable expansion device based on a sensed temperature. The system is further configured to apply a second force to a valve of the variable expansion device via the force applied to the pin and to output a second portion of the refrigerant to a second downstream HVAC component at a variable flow rate based on the second force using the valve of the variable expansion device.

Abstract: A hemodynamic monitoring system comprising an ultrasound system comprising a transesophageal ultrasound probe and a computer system coupled to the ultrasound system. The computer system can be configured to calculate an image quality parameter and/or a hemodynamic parameter by segmenting images obtained via the hemodynamic monitoring system to identify a selected anatomical structure therein. The image quality and hemodynamic parameters can be displayed to users, such as medical staff, in connection with the ultrasound images.

Abstract: Apparatus for performing impedance measurements on a subject. The apparatus includes a first processing system for determining an impedance measurement procedure and determining instructions corresponding to the measurement procedure. A second processing system is provided for receiving the instructions, using the instructions to generate control signals, with the control signals being used to apply one or more signals to the subject. The second processing system then receives first data indicative of the one or more signals applied to the subject, second data indicative of one or more signals measured across the subject and performs at least preliminary processing of the first and second data to thereby allow impedance values to be determined.

Abstract: A network node in a peer-to-peer network of nodes includes at least one processor, at least one memory, and at least one network interface. The at least one processor is configured to receive a request to transfer a security token and execute a plurality of compliance rules associated with the security token. At least one of the compliance rules is implemented using at least one smart contract. The at least one smart contract references a global registry. The at least one processor is also configured to transfer the security token based on the execution of the compliance rules. The global registry includes personally identifiable information (PII) hash(es) for each of at least one investor associated with the transfer of the security token. The hashes are committed to the distributed ledger and updated when PII of a respective one of the at least one investor changes.

Abstract: Methods, devices and systems are disclosed for inter-app communications between software applications on a mobile communications device. In one aspect, a computer-readable medium on a mobile computing device comprising an inter-application communication data structure to facilitate transitioning and distributing data between software applications in a shared app group for an operating system of the mobile computing device includes a scheme field of the data structure providing a scheme id associated with a target software app to transition to from a source software app, wherein the scheme id is listed on a scheme list stored with the source software app; and a payload field of the data structure providing data and/or an identification where to access data in a shared file system accessible to the software applications in the shared app group, wherein the payload field is encrypted.

Abstract: Disclosed is the differential application of scalars to compensate pixel degradation. Input image data is associated with a commanded luminance at each of a plurality of pixels. A degradation value is determined for each pixel. Based on the degradation value, an elevated drive current is determined to produce commanded luminance at the pixel. A required scalar is determined for each pixel to hold the elevated drive current from exceeding a drive current threshold. An applied scalar for each pixel is determined for each pixel to be applied to the elevated drive current. For at least some pixels, the applied scalar for a first pixel is based at least on [I] the required scalar of a second pixel and [2] a spatial relationship between the first pixel and the second pixel. Applied scalars are then used to output corrected imagery.

Abstract: An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.