Patents by Inventor Scott Altmann

Scott Altmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120084871
    Abstract: The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
    Type: Application
    Filed: February 14, 2011
    Publication date: April 5, 2012
    Applicant: Schering Corporation
    Inventors: Scott Altmann, Xiaorui Yao, Kim Anne O'Neill, Brian E. Hawes
  • Patent number: 7910698
    Abstract: The present invention provides, in part, NPC1L1 from various species. Methods of using the NPC1L1 polypeptides and polynucleotide set forth herein, e.g., in screening assays, are also set forth.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: March 22, 2011
    Assignee: Schering Corporation
    Inventors: Scott Altmann, Xiaorui Yao, Kim Ann O'Neill, Brian E. Hawes
  • Publication number: 20070105141
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Application
    Filed: October 25, 2006
    Publication date: May 10, 2007
    Applicant: Schering Corporation
    Inventors: Scott Altmann, Duane Burnett, Harry Davis, Michael Graziano, Maureen Laverty, Xiaorui Yao
  • Publication number: 20070021592
    Abstract: The present invention provides human, rat and mouse NPC1L1 polypeptides and polynucleotides encoding the polypeptides. Also provided are methods for detecting agonists and antagonists of NPC1L1. Inhibitors of NPC1L1 can be used for inhibiting intestinal cholesterol absorption in a subject.
    Type: Application
    Filed: September 19, 2006
    Publication date: January 25, 2007
    Inventors: Scott Altmann, Nicholas Murgolo, Luquan Wang, Michael Graziano
  • Publication number: 20050208568
    Abstract: The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
    Type: Application
    Filed: May 6, 2005
    Publication date: September 22, 2005
    Inventors: Scott Altmann, Duane Burnett, Harry Davis, Michael Graziano, Maureen Laverty, Xiaorui Yao