Abstract: A multiparticulate for controlled release of a drug comprises crystalline drug, a glyceride having at least one alkylate substituent of at least 16 carbon atoms, and a poloxamer, wherein at least 70 wt % of the drug in the multiparticulate is crystalline.

Abstract: Reduced levels of drug degradation in drug-containing multiparticulates are obtained by an extrusion/melt-congeal process.

Abstract: A pharmaceutical composition is disclosed which comprises multiparticulates wherein said multiparticulates further comprise an azithromycin core and an enteric coating disposed upon said azithromycin core.

Abstract: Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed.

Abstract: EVAL microporous hydrophilic hollow fiber membranes are formed from a casting dope that includes low and high molecular weight pore-formers. Post-fabrication treatment includes stretching, hot water soaking and crosslinking.

Abstract: Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed.

Abstract: Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed.

Abstract: Solvent-resistant polybenzimidazole membranes, methods of making them and crosslinking them and composite membranes and hollow fiber membrane modules from them are disclosed.

Abstract: A system for the ultrapurification of organic solvents comprising (1) a membrane-based vapor permeation step for selective removal of water vapor from the solvent, wherein a countercurrent sweep stream is used that has a particular partial pressure of water vapor, (2) a filtration step for selective removal of particulates, and (3) an ion exchange step for selective removal of ionic species.

Abstract: Membrane-based vapor permeation system for selective removal of a vapor from a fluid feed stream, wherein a countercurrent sweep stream is used that has a particular partial pressure of the vapor to be removed.

Abstract: A vapor permeation method and apparatus for removing a vapor from a vaporous feed stream, the method and apparatus utilizing highly solvent-resistant composite hollow fiber membranes and a permeate flow countercurrent to the feed flow, wherein the support of the composite membrane is formed by solution casting and has been rendered sufficiently solvent-resistant by a post-casting step to retain at least 20 of its burst pressure when soaked in the solvent used to cast the support.

Abstract: An asymmetric microporous membrane with exceptional solvent resistance and highly desirable permeability is disclosed. The membrane is made by a solution-casting or solution-spinning process from a copolyamic acid comprising the condensation reaction product in a solvent of at least three reactants selected from certain diamines and dianhydrides and post-treated to imidize and in some cases cross-link the copolyamic acid. The membrane is useful as an uncoated membrane for ultrafiltration, microfiltration, and membrane contactor applications, or may be used as a support for a permselective coating to form a composite membrane useful in gas separations, reverse osmosis, nanofiltration, pervaporation, or vapor permeation.

Abstract: A process for the dehydration of a vaporous mixture. The basic process involves directing a predominantly condensable water vapor-containing vaporous mixture against the feed side of a membrane while maintaining the feed near saturation without condensing it, directing a condensable vapor sweep stream past the permeate side of the membrane in a countercurrent flow, thereby transporting water vapor in the vaporous mixture from the feed side to the permeate side of the membrane to form a noncondensed combined permeate side mixture of condensable vapor and transported water vapor.

Abstract: A process for the removal of at least one non-water vapor component of a vaporous mixture, the basic process comprising directing a vaporous mixture against the feed side of a membrane, directing a condensable vapor sweep stream past the permeate side of the membrane in a manner such that the flow of the condensable vapor sweep is substantially countercurrent to the flow of the vaporous mixture, thereby transporting at least a portion of at least one non-water vapor component of the vaporous mixture from the feed side to the permeate side of the membrane to form a combined permeate side mixture of condensable vapor and at least one non-water vapor transported component.

Abstract: A method for making a chlorine-resistant composite polyamide membrane having high organic rejection, the essential step of which comprises treating a conventional composite membrane with an acyl halide. The novel membrane is especially suitable for the treatment of water containing chlorine or lower molecular weight organic compounds.

Abstract: Improved methods of rendering PVDF membranes hydrophilic are disclosed.

Abstract: There is described a process for the removal of at least one component of a liquid mixture, the basic process comprising directing a liquid mixture against the feed side of a membrane, directing a condensable vapor sweep stream past the permeate side of the membrane in a manner such that the flow of the condensable vapor sweep is substantially countercurrent to the flow of the liquid mixture, thereby transporting at least a portion of at least one component of the liquid mixture from the feed side to the permeate side of the membrane to form a combined permeate side mixture of condensable vapor and at least one transported component.

Abstract: A process for removing and recovering a condensable vapor from a gas stream by a membrane contactor is disclosed wherein a gas stream containing a condensable vapor is circulated on one side of hollow fiber membranes while cool extraction fluid is circulated on the other side under a total pressure differential, thereby condensing the condensable vapor in the gas stream, the condensed vapor permeating the membrane and becoming entrained in the cool extraction fluid.

Abstract: A gas dehydration method and apparatus are disclosed which utilize lumen-side feed, hydrophilic polymer-inside-coated, thin-film composite hollow fiber membranes, the support fiber of which is highly permeable, such composite membranes being used in a module wherein the permeate flows countercurrent to the flow of the feed, and in which dried raffinate gas is mixed with water-containing permeate at a point opposite the feed end of the module.

Abstract: Composite RO membranes having good resistance to halogen attack and high fluxes are disclosed, the composite membranes comprising a microporous polymeric support with an interfacially polymerized salt-rejecting layer thereon comprising an aromatic aliphatic diamide/diimide.