Abstract: An apparatus, system and method for performing a ventriculostomy using an ultrasound probe is disclosed. A head portion of the probe is connected to a handle portion at a proximal end of the head portion. A transducer is mounted in a distal end of the head portion to transmit ultrasound waves into the patient. The head portion includes a conduit portion arranged to accept and to accurately direct a catheter into the body of the patient in a direction parallel to the direction of the ultrasound waves. The head portion is sized to fit into a conventionally-sized craniotomy. An adjustment mechanism connects the head portion to the handle portion for selectively adjusting the angle between the handle portion and the head portion. A sterile sheath having an integral conduit assembly for mounting to the head is optionally provided. An illuminator is optionally provided on the probe.