Patents by Inventor Scott B. Reeder

Scott B. Reeder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7924003
    Abstract: NMR signal contributions from water and fat are separated using a model of the fat resonant frequency spectrum that has multiple resonant peaks. The relative frequencies of the multiple fat spectrum peaks are known a priori and their relative amplitudes are determined using a self-calibration process. With the determined relative amplitudes of the fat spectrum peaks, acquired NMR signals are modeled. Using this model and NMR signal data acquired at a plurality of echo times (TE), the signal contribution from multiple fat spectrum peaks is separated from the acquired NMR signal data. A combined image is alternatively produced from weighted contributions of the separated water and fat images. Additionally, a more accurate estimation of the apparent relaxation time and rate (T*2 and R*2, respectively) is alternatively performed.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: April 12, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Huanzhou Yu, Scott B. Reeder
  • Patent number: 7804299
    Abstract: A preparatory pulse sequence is applied prior to an imaging pulse sequence during a diffusion-weighted MRI scan. The preparatory pulse sequence diffusion weights the longitudinal magnetization using a gradient waveform that is first moment nulled to reduce image artifacts caused by patient motion.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: September 28, 2010
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Scott B. Reeder, Reed Busse, Jean H. Brittain
  • Publication number: 20100185081
    Abstract: The in vivo measurement of tissue temperature is performed during a medical procedure using an MRI system. Fat and Water images are acquired at each temperature measurement time and corresponding phase images are produced. A temperature map is produced by subtracting the phase at each Fat image pixel from the corresponding pixel in the Water phase image to improve measurement accuracy in tissues with fat/water mixtures.
    Type: Application
    Filed: May 1, 2008
    Publication date: July 22, 2010
    Inventors: Brian J. Soher, Scott B. Reeder
  • Patent number: 7741842
    Abstract: A method for generating a calibrated parallel magnetic resonance image is provided in a manifestation of the invention. A magnetic resonance imaging excitation is applied. A plurality of echoes at different echo times (TE) is acquired. The acquired plurality of echoes from different echo times is used to create a chemical shift corrected calibration map.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: June 22, 2010
    Assignees: The Board of Trustees of the Leland Stanford Junior University, General Electric Company, Beth Israel Deaconess Medical Center
    Inventors: Charles A. McKenzie, Scott B. Reeder, Ann Shimakawa
  • Publication number: 20090261823
    Abstract: NMR signal contributions from water and fat are separated using a model of the fat resonant frequency spectrum that has multiple resonant peaks. The relative frequencies of the multiple fat spectrum peaks are known a priori and their relative amplitudes are determined using a self-calibration process. With the determined relative amplitudes of the fat spectrum peaks, acquired NMR signals are modeled. Using this model and NMR signal data acquired at a plurality of echo times (TE), the signal contribution from multiple fat spectrum peaks is separated from the acquired NMR signal data. A combined image is alternatively produced from weighted contributions of the separated water and fat images. Additionally, a more accurate estimation of the apparent relaxation time and rate (T2* and R2*, respectively) is alternatively performed.
    Type: Application
    Filed: April 17, 2008
    Publication date: October 22, 2009
    Inventors: Huanzhou Yu, Scott B. Reeder
  • Patent number: 7592810
    Abstract: A method for generating a magnetic resonance images is provided. A first species signal for a first species is generated from magnetic resonance data. A second signal is generated from the magnetic resonance data. The first species signal is combined with the second signal to provide a recombined image. The recombined image may be displayed.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: September 22, 2009
    Assignees: The Board of Trustees of the Leland Stanford Junior University, General Electric Company
    Inventors: Scott B. Reeder, Charles A. McKenzie, Jean H. Brittain
  • Patent number: 7592807
    Abstract: A method of separating signals from at least two species in a body using echo-coherent time magnetic resonance imaging is provided. A plurality of echo signals is acquired at acquisition times optimized based on the noise properties of images with different variance with possibly correlated noise resulting in possibly asymmetrically positioned images with respect to an echo time. The plurality of echo signals is combined iteratively by using a maximum likelihood decomposition algorithm for non-identically distributed noise.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: September 22, 2009
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Angel R. Pineda, Charles A. McKenzie, Huanzhou Yu, Scott B. Reeder
  • Patent number: 7508211
    Abstract: A method for generating a magnetic resonance images is provided. A magnetic resonance imaging excitation is applied. A plurality of magnetic resonance image signals is acquired. The plurality of image signals is combined iteratively by using a regularized decomposition algorithm. An image created from combining the plurality of image signals iteratively is displayed.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: March 24, 2009
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Zhifei Wen, Angel R. Pineda, Huanzhou Yu, Scott B. Reeder, Norbert J. Pelc
  • Patent number: 7486074
    Abstract: A method for generating a self-calibrating parallel multiecho magnetic resonance image is provided. A magnetic resonance imaging excitation is applied. A first echo at a first echo time in a first pattern is acquired. A second echo at a second echo time different from the first echo phase in a second pattern different from the first pattern is acquired. The acquired first echo and acquired second echo are used to generate an image in an image pattern, wherein none of the acquired echoes for generating the image have the same pattern as the image pattern.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: February 3, 2009
    Assignees: The Board of Trustees of the Leland Stanford Junior University, General Electric Company
    Inventors: Charles A. McKenzie, Anja Brau, Huanzhou Yu, Scott B. Reeder, Jean H. Brittain, Ann Shimakawa
  • Patent number: 7486073
    Abstract: A method for generating dynamic magnetic resonance images is provided. A cyclical magnetic resonance imaging excitation is applied for a plurality of cycles at a cycle rate. A plurality of magnetic resonance image echoes is acquired for each cycle. A plurality of frames of images is generated from the acquired plurality of magnetic resonance echoes at a frame rate that is at least twice the cycle rate, wherein each frame of the plurality of frames is generated from a plurality of echoes and wherein some of the plurality of frames are generated from magnetic resonance image echoes of adjacent cycles.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: February 3, 2009
    Assignees: The Board of Trustees of the Leland Stanford Junior University, General Electric Company
    Inventors: Huanzhou Yu, Charles A. McKenzie, Jean H. Brittain, Norbert J. Pelc, Scott B. Reeder
  • Patent number: 7480525
    Abstract: The acquisition of multiple images at slightly different time shifts from the spin echo (or from TE=0 for gradient echo sequences), allows the separation of on-resonance spins from off-resonance spins by encoding this information in the received signal. The excitation pulse can be a standard broadband excitation that will excite all spins. The separation of on- and off-resonance spins is then performed on the received signal. The polar and equatorial lobes of a magnetic particle such as SPIO produce signals from excited water molecules near the particle which are frequency offset above and below the frequency of signals from water molecules unaffected by the particle.
    Type: Grant
    Filed: May 1, 2006
    Date of Patent: January 20, 2009
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Scott B. Reeder, Garry E. Gold
  • Patent number: 7468605
    Abstract: A method for generating a magnetic resonance image is provided. A magnetic resonance imaging excitation is applied for a plurality of cycles at a cycle rate. A plurality of magnetic resonance image echoes is acquired for each cycle. A decay map is estimated from the plurality of magnetic resonance image echoes for each cycle. The estimated decay map is used to generate an image for at least two different species.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: December 23, 2008
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Huanzhou Yu, Scott B. Reeder, Charles A. McKenzie, Angel R. Pineda
  • Publication number: 20080275329
    Abstract: A preparatory pulse sequence is applied prior to an imaging pulse sequence during a diffusion-weighted MRI scan. The preparatory pulse sequence diffusion weights the longitudinal magnetization using a gradient waveform that is first moment nulled to reduce image artifacts caused by patient motion.
    Type: Application
    Filed: May 4, 2007
    Publication date: November 6, 2008
    Inventors: Scott B. Reeder, Reed Busse, Jean H. Brittain
  • Patent number: 7375522
    Abstract: A water and fat image are acquired using a pulse sequence in which NMR signals for one image data set are acquired with a readout gradient of one polarity and NMR signals for the other image data set are acquired with a readout gradient of the opposite polarity. A misalignment of fat signals caused by chemical shift is corrected by calculating separate water and fat image data sets in k-space and then transforming them to real space images.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: May 20, 2008
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Scott B. Reeder
  • Patent number: 7349729
    Abstract: A multi-point chemical species (e.g., water, fat) separation process which is compatible with rapid gradient echo imaging such as SSFP uses an iterative least squares method that decomposes water and fat images from source images acquired at short echo time increments. The single coil algorithm extends to multi-coil reconstruction with minimal additional complexity.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: March 25, 2008
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Scott B. Reeder, Norbert J. Pelc
  • Publication number: 20080048657
    Abstract: A water and fat image are acquired using a pulse sequence in which NMR signals for one image data set are acquired with a readout gradient of one polarity and NMR signals for the other image data set are acquired with a readout gradient of the opposite polarity. A misalignment of fat signals caused by chemical shift is corrected by calculating separate water and fat image data sets in k-space and then transforming them to real space images.
    Type: Application
    Filed: August 28, 2006
    Publication date: February 28, 2008
    Inventor: Scott B. Reeder
  • Patent number: 7298144
    Abstract: Homodyne image reconstruction is combined with an iterative decomposition of water and fat from MR signals obtained from a partial k-space signal acquisition in order to maximize the resolution of calculated water and fat images. The method includes asymmetrical acquisition of under-sampled MRI data, obtaining low resolution images, and then estimating a magnetic field map and phase maps of water and fat image signals from the low resolution images. The acquired data is again filtered and Fourier transformed to obtain an estimate of combined fat and water signals using the estimated magnetic field map and phase maps. Water and fat images are then estimated from which phases of the water and fat images are determined. The real parts of the water and fat images are then used in calculating water and fat images using a homodyne process.
    Type: Grant
    Filed: October 18, 2005
    Date of Patent: November 20, 2007
    Assignees: The Board of Trustee of the Leland Stanford Junior University, General Electric Company
    Inventors: Scott B. Reeder, Brian A. Hargreaves, Jean H. Brittain
  • Patent number: 7176683
    Abstract: A method of separating signals from water and lipid in a body using spin-echo magnetic resonance imaging comprising steps of acquiring image signals at three acquisition times asymmetrically positioned with respect to a spin-echo time, the three acquisition times being separated by 2?/3 and the middle signal acquisition is centered at ?/2+?k where k is an integer, and combining the plurality of image signals iterative using a least squares decomposition method.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: February 13, 2007
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Scott B. Reeder, Angel R. Pineda
  • Patent number: 6856134
    Abstract: A generalized multi-point fat-water separation process is combined with steady-state free precession (SSFP) to obtain high quality images of articular cartilage with reduced imaging time.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: February 15, 2005
    Assignee: The Board of Trustees of The Leland Stanford Junior University
    Inventors: Scott B. Reeder, Norbert J. Pelc
  • Patent number: 6188219
    Abstract: The invention provides a method of magnetic resonance imaging. A magnetic resonance imaging apparatus having a plurality of gradient axes is employed. A plurality of imaging planes are employed with respect to the gradient axes. A plurality of gradient referencing pre-scans are executed for the imaging planes to provide a plurality of calibration correction values for the imaging planes. A specimen is employed with respect to the gradient axes. An imaging plane is selected with respect to the specimen, and a main magnetic field is established with respect to the specimen. Radio frequency pulses are applied to the specimen to produce magnetic resonance signals. The calibration correction values for the selected imaging plane are employed to adjust a plurality of gradient waveforms. The gradient waveforms are output as a plurality of magnetic field gradients with respect to the gradient axes.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: February 13, 2001
    Assignee: The Johns Hopkins University
    Inventors: Scott B. Reeder, Ergin Atalar, Anthony Z. Faranesh, Elliot R. McVeigh