Patents by Inventor Scott Borthwick

Scott Borthwick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 2-amino-3-(2-amino-phenylsulfanyl)-propionic acids
    Patent number: 7011960
    Abstract: The present invention relates to a new process for the preparation compounds of formula I wherein R1, R2, R3 and n are as described in the description which process comprises reacting compounds of formula II wherein R1, R2, R3, n and R4 are as described in the description, with a protease in an aqueous system containing an organic co-solvent. The compound of formula I are useful for the preparation of 1,5-benzothiazepines which are useful as enzyme inhibitors, such as protease, interleukin-1?-converting enzyme, elastase or angiotensin converting enzyme, GPCR antagonists (cholecystokinin, angiotensin II receptor).
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: March 14, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Konrad Bleicher, Scott Borthwick, Hans Iding, Mark Rogers-Evans, Stefan Schmid, Han Min Tong, Beat Wirz
  • Substituted 2-amino-3- (2-amino-phenylsulfanyl) -propionic acids
    Publication number: 20030119152
    Abstract: The present invention relates to a new process for the preparation compounds of formula I 1
    Type: Application
    Filed: September 23, 2002
    Publication date: June 26, 2003
    Inventors: Konrad Bleicher, Scott Borthwick, Hans Iding, Mark Rogers-Evans, Stefan Schmid, Han Min Tong, Beat Wirz