Patents by Inventor Scott Bultman

Scott Bultman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted quinolinylcyclohexylpropanamide compounds and improved methods for their preparation
    Patent number: 11919863
    Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: March 5, 2024
    Assignee: Bristol-Myers Squibb Company
    Inventors: Albert J. Delmonte, Benjamin M. Cohen, Kenneth Joseph Fraunhoffer, Sergei Kolotuchin, Francisco Gonzalez-Bobes, Gregory Louis Beutner, Adam Joseph Freitag, Michael Scott Bultman, Yu Fan, Prantik Maity, Ian Scott Young, Hilary Plake Beck, Maksim Osipov, Jay Patrick Powers, Maureen Kay Reilly, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky
  • SUBSTITUTED QUINOLINYLCYCLOHEXYLPROPANAMIDE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20220267273
    Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.
    Type: Application
    Filed: December 16, 2021
    Publication date: August 25, 2022
    Inventors: Albert J. DELMONTE, Benjamin M. COHEN, Kenneth Joseph FRAUNHOFFER, Sergei KOLOTUCHIN, Francisco GONZALEZ-BOBES, Gregory Louis BEUTNER, Adam Joseph FREITAG, Michael Scott BULTMAN, Yu FAN, Prantik MAITY, Ian Scott YOUNG, Hilary Plake BECK, Maksim OSIPOV, Jay Patrick POWERS, Maureen Kay REILLY, Hunter Paul SHUNATONA, James Ross WALKER, Mikhail ZIBINSKY
  • SUBSTITUTED QUINOLINYLCYCLOHEXYLPROPANAMIDE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20220127233
    Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.
    Type: Application
    Filed: November 12, 2021
    Publication date: April 28, 2022
    Inventors: Albert J. DELMONTE, Benjamin M. COHEN, Kenneth Joseph FRAUNHOFFER, Sergei KOLOTUCHIN, Francisco GONZALEZ-BOBES, Gregory Louis BEUTNER, Adam Joseph FREITAG, Michael Scott BULTMAN, Yu FAN, Prantik MAITY, Ian Scott YOUNG, Hilary Plake BECK, Maksim OSIPOV, Jay Patrick POWERS, Maureen Kay REILLY, Hunter Paul SHUNATONA, James Ross WALKER, Mikhail ZIBINSKY
  • Substituted quinolinylcyclohexylpropanamide compounds and improved methods for their preparation
    Patent number: 11236048
    Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: February 1, 2022
    Assignee: Bristol-Myers Squibb Company
    Inventors: Albert J. Delmonte, Benjamin M. Cohen, Kenneth Joseph Fraunhoffer, Sergei Kolotuchin, Francisco Gonzalez-Bobes, Gregory Louis Beutner, Adam Joseph Freitag, Michael Scott Bultman, Yu Fan, Prantik Maity, Ian Scott Young, Hilary Plake Beck, Maksim Osipov, Jay Patrick Powers, Maureen Kay Reilly, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky
  • Methods to generate gastrointestinal epithelial tissue constructs
    Patent number: 11193110
    Abstract: A method of making a live cell construct is carried out by: (a) providing a non-cellular support having a top surface and a bottom surface, (b) contacting live undifferentiated cells to the non-cellular support, and then (c) propagating a gastrointestinal epithelial cell monolayer on said top surface. In some embodiments, the live cells in the monolayer include: (i) undifferentiated cells (e.g., stem or progenitor cells); and (ii) optionally, but in some embodiments preferably, differentiated cells (e.g., enterocytes, Paneth cells, enteroendocrine cells, tuft cells, microcells, intra-epithelial lymphocytes, and/or goblet cells). Constructs formed by such methods and methods of using the same (e.g., in high through-put screening) are also described.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: December 7, 2021
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Nancy Allbritton, Yuli Wang, Christopher Sims, Scott Magness, Scott Bultman
  • SUBSTITUTED QUINOLINYLCYCLOHEXYLPROPANAMIDE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20200123109
    Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.
    Type: Application
    Filed: June 29, 2018
    Publication date: April 23, 2020
    Inventors: Albert J. DELMONTE, Benjamin M. COHEN, Kenneth Joseph FRAUNHOFFER, Sergei KOLOTUCHIN, Francisco GONZALEZ-BOBES, Gregory Louis BEUTNER, Adam Joseph FREITAG, Michael Scott BULTMAN, Yu FAN, Prantik MAITY, Ian Scott YOUNG, Hilary Plake BECK, Maksim OSIPOV, Jay Patrick POWERS, Maureen Kay REILLY, Hunter Paul SHUNATONA, James Ross WALKER, Mikhail ZIBINSKY
  • METHODS AND COMPOSITIONS FOR TREATMENT OF HEART FAILURE
    Publication number: 20180140722
    Abstract: The present invention relates to methods and compositions for treating heart failure in a subject using histone deacetylase (HDAC) inhibitors and/or histone acetyltransferases (HAT) activators.
    Type: Application
    Filed: April 6, 2016
    Publication date: May 24, 2018
    Inventors: Monte Willis, Scott Bultman
  • METHODS TO GENERATE GASTROINTESTINAL EPITHELIAL TISSUE CONSTRUCTS
    Publication number: 20180002672
    Abstract: A method of making a live cell construct is carried out by: (a) providing a non-cellular support having a top surface and a bottom surface, (b) contacting live undifferentiated cells to the non-cellular support, and then (c) propagating a gastrointestinal epithelial cell monolayer on said top surface. In some embodiments, the live cells in the monolayer include: (i) undifferentiated cells (e.g., stem or progenitor cells); and (ii) optionally, but in some embodiments preferably, differentiated cells (e.g., enterocytes, Paneth cells, enteroendocrine cells, tuft cells, microcells, intra-epithelial lymphocytes, and/or goblet cells). Constructs formed by such methods and methods of using the same (e.g., in high through-put screening) are also described.
    Type: Application
    Filed: January 29, 2016
    Publication date: January 4, 2018
    Inventors: Nancy Allbritton, Yuli Wang, Christopher Sims, Scott Magness, Scott Bultman