Patents by Inventor Scott C. Winder

Scott C. Winder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and solvent vehicles for reagent delivery in oligonucleotide synthesis using automated pulse jetting devices
    Patent number: 5874554
    Abstract: Solvent vehicles and methods of their use in the pulse jet delivery of reagents in automated oligonucleotide synthesis by the solid-phase phosphoramidite method are provided. For pulse jet delivery of the activated monomer, acetonitrile in combination with at least one stabilizer co-solvent is employed as the solvent vehicle, where the stabilizer co-solvent is an inert, organic solvent having a boiling point of at least 100.degree. C. For pulse jet delivery of the detritylation reagent, a mono- or disubstituted methane is employed as the solvent vehicle, where substituents have a molecular weight greater than 36 daltons. Use of the solvent vehicles according to the subject invention provides for reduced reagent precipitation in the pulse jet tubes and improved results.
    Type: Grant
    Filed: December 13, 1996
    Date of Patent: February 23, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Ronald C. Gamble, Thomas P. Theriault, Scott C. Winder