Patents by Inventor Scott Charles Bolton

Scott Charles Bolton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tyrosine kinase biosensors and methods of use
    Patent number: 10150984
    Abstract: Disclosed are compositions and methods for measuring tyrosine kinase activity.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: December 11, 2018
    Inventors: Laurie L Parker, Andrew Michael Lipchik, Scott Charles Bolton
  • TYROSINE KINASE BIOSENSORS AND METHODS OF USE
    Publication number: 20170342461
    Abstract: Disclosed are compositions and methods for measuring tyrosine kinase activity.
    Type: Application
    Filed: November 22, 2016
    Publication date: November 30, 2017
    Applicant: Purdue Research Foundation
    Inventors: Laurie L PARKER, Andrew Michael LIPCHIK, Scott Charles BOLTON
  • Tyrosine kinase biosensors and methods of use
    Patent number: 9499854
    Abstract: The claims describe a process for designing and validating peptide-based substrates for a specified kinase. The process uses a rational approach to design peptides with a specific amino acid that is phosphorylated by a target tyrosine kinase, and upon phosphorylation shows an increased affinity for a lanthanide ion that results in an enhanced fluorescent signal. The process uses kinase specific input data sets, encodes the input into positional scoring matrices, analyses the positional scoring matrices in order to generate a candidate list of peptide sequences, compares the peptide sequences in the candidate list, substitutes residues at non-selective positions in selections from the candidate list with terbium binding residues, and then screens the substituted selections with different kinases in vitro.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: November 22, 2016
    Assignee: Purdue Research Foundation
    Inventors: Laurie Louise Parker, Andrew M. Lipchik, Scott Charles Bolton
  • TYROSINE KINASE BIOSENSORS AND METHODS OF USE
    Publication number: 20130231265
    Abstract: Disclosed are compositions and methods for measuring tyrosine kinase activity.
    Type: Application
    Filed: February 7, 2013
    Publication date: September 5, 2013
    Inventors: Laurie Louise Parker, Andrew Michael Lipchik, Scott Charles Bolton
  • Bit allocation method for improved audio quality perception using psychoacoustic parameters
    Patent number: 5761636
    Abstract: Audio quality perception can be improved in an audio compression system 100 by defining a frequency subband threshold 205. With the frequency subband threshold 205, each frequency subband favorable to the threshold will be allocated at least a predetermined number of bits while frequency subbands unfavorable to the threshold will receive no bit allocations. This determination is made on an audio frame by audio frame basis, or upon change of the audio compression ratio, since changing any of the parameters: bitrate, sampling rate and coding mode changes the compression ratio.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: June 2, 1998
    Assignee: Motorola, Inc.
    Inventors: Scott Charles Bolton, James Leonard Fiocca