Abstract: Methods and apparatus for controlling a heart pump system are described. The heart pump system includes a first heart pump and a second heart pump and a controller. The controller includes a data interface configured to receive first data from the first heart pump and second data from the second heart pump, and at least one computer processor. The at least one computer process is programmed to display in a first portion of a user interface, an indication of the first data, display in a second portion of the user interface, an indication of the second data, and control an operation of the first heart pump and/or the second heart pump.

Abstract: Systems and methods are provided herein for treating a patient in cardiogenic shock. An intravascular heart pump system is inserted into vasculature of the patient. The heart pump system has a cannula, pump outlet, pump inlet, and rotor. The heart pump system is positioned within the patient such that the cannula extends across the patient's aortic valve, the pump inlet is located within the patient's left ventricle, and the pump outlet is located within the patient's aorta. Data related to time-varying parameters of the heart pump system is acquired from the heart pump system. A plurality of features are extracted from the data. A probability of survival of the patient is determined based on the plurality of features and using a prediction model. The heart pump system is operated to treat the patient.

Abstract: Various devices, systems, and methods are disclosed. The method may include determining a body surface area of a patient (who may have a body surface area of about 0.6 m2 to about 1.3 m2), selecting a blood pump from a plurality of differently sized blood pumps based on the body surface area of the patient, implanting the blood pump, and activating the blood pump to provide support to the patient. The selected blood pump may have a cannula connecting an inlet and an outlet. The cannula may have a bend and a cannula length measuring an axial length between the inlet and the outlet. The cannula length may be between about 30 mm to about 46 mm if the body surface area is less than 0.9 m2.

Abstract: Techniques for delaying initiation of coagulation and suppressing fibrin formation may be provided. The disclosed techniques may include providing a percutaneous blood pump that may include a metal or ceramic surface (such as a surface of a shaft, bearing, rotor, stator, etc.) that has been modified with a bifunctional modifier. The modified surface may be within a motor section and/or pump section of the blood pump. The modified surface may be configured to interact with blood. When blood is allowed to interact with the modified surface, a desirable microenvironment may be formed. The bifunctional modifier may be a functionalized aminosilane, a functionalized aminosiloxane, and/or a functionalized silanetriol. The blood pump may be configured to have a purge fluid pass through at least a portion of the motor section and/or the pump section. The purge fluid may be free of anticoagulants.

Abstract: Systems and methods are provided herein for treating a patient in cardiogenic shock. An intravascular heart pump system is inserted into vasculature of the patient. The heart pump system has a cannula, pump outlet, pump inlet, and rotor. The heart pump system is positioned within the patient such that the cannula extends across the patient's aortic valve, the pump inlet is located within the patient's left ventricle, and the pump outlet is located within the patient's aorta. Data related to time-varying parameters of the heart pump system is acquired from the heart pump system. A plurality of features are extracted from the data. A probability of survival of the patient is determined based on the plurality of features and using a prediction model. The heart pump system is operated to treat the patient.

Abstract: Devices, system, and methods are provided based on a technique for purging a blood pump. The technique may include providing a blood pump having an impeller and providing a fluid comprising a bicarbonate. The technique may include flowing the fluid through a first gap between a bearing and an outer surface of a rotatable shaft coupled to the impeller, the bearing and gap being disposed within a lumen of a tubular member and depending on the flow rate of the fluid and the speed of the impeller, the fluid may flow through the first gap and into a second gap between the bearing and a surface of the impeller facing the bearing. The bicarbonate reduces denaturation and adsorption of any blood proteins in the gap(s).

Abstract: Systems and methods are provided herein for treating a patient in cardiogenic shock. An intravascular heart pump system is inserted into vasculature of the patient. The heart pump system has a cannula, pump outlet, pump inlet, and rotor. The heart pump system is positioned within the patient such that the cannula extends across the patient's aortic valve, the pump inlet is located within the patient's left ventricle, and the pump outlet is located within the patient's aorta. Data related to time-varying parameters of the heart pump system is acquired from the heart pump system. A plurality of features are extracted from the data. A probability of survival of the patient is determined based on the plurality of features and using a prediction model. The heart pump system is operated to treat the patient.

Abstract: Systems and methods are provided herein for treating a patient in cardiogenic shock. An intravascular heart pump system is inserted into vasculature of the patient. The heart pump system has a cannula, pump outlet, pump inlet, and rotor. The heart pump system is positioned within the patient such that the cannula extends across the patient's aortic valve, the pump inlet is located within the patient's left ventricle, and the pump outlet is located within the patient's aorta. Data related to time-varying parameters of the heart pump system is acquired from the heart pump system. A plurality of features are extracted from the data. A probability of survival of the patient is determined based on the plurality of features and using a prediction model. The heart pump system is operated to treat the patient.

Abstract: Systems and methods are provided herein for treating a patient in cardiogenic shock. An intravascular heart pump system is inserted into vasculature of the patient. The heart pump system has a cannula, pump outlet, pump inlet, and rotor. The heart pump system is positioned within the patient such that the cannula extends across the patient's aortic valve, the pump inlet is located within the patient's left ventricle, and the pump outlet is located within the patient's aorta. Data related to time-varying parameters of the heart pump system is acquired from the heart pump system. A plurality of features are extracted from the data. A probability of survival of the patient is determined based on the plurality of features and using a prediction model. The heart pump system is operated to treat the patient.

Abstract: Disclosed are wearable ultrasound probes for use in trauma triage and assessment. The probes include a finger-receiving aperture at a proximal end, a first ultrasound array disposed at a distal end, wherein the first ultrasound array is angled toward the palmar side about 60-105 degrees from the longitudinal axis, and a second ultrasound array disposed adjacent the distal end and proximal to the first ultrasound array, wherein the second ultrasound array is angled toward the palmar side about 10-50 degrees from the longitudinal axis, wherein the first ultrasound array comprises a phased array and the second ultrasound array comprises a linear array. Also disclosed are systems, methods, and finger-gripping elements that help retain the finger-mounted probes during use.

Abstract: Disclosed are portable ultrasound systems for use in trauma triage and assessment, such as for performing an eFAST exam. The systems include a tablet-based or mobile phone-based graphical user interface (GUI).

Abstract: Systems and methods are provided herein for treating a patient in cardiogenic shock. An intravascular heart pump system is inserted into vasculature of the patient. The heart pump system has a cannula, pump outlet, pump inlet, and rotor. The heart pump system is positioned within the patient such that the cannula extends across the patient's aortic valve, the pump inlet is located within the patient's left ventricle, and the pump outlet is located within the patient's aorta. Data related to time-varying parameters of the heart pump system is acquired from the heart pump system. A plurality of features are extracted from the data. A probability of survival of the patient is determined based on the plurality of features and using a prediction model. The heart pump system is operated to treat the patient.

Abstract: A prosthetic apparatus is disclosed including: a tubular stent disposed about a longitudinal axis and extending from a proximal end to a distal end, the stent defining a tubular passage between the ends. The tubular stent has a proximal portion, a distal portion, and a middle portion located between the proximal and distal portions. The proximal and distal portions each comprise a mesh of support struts forming at least one ring of open elements disposed about the longitudinal axis. The middle portion features open regions which reduce or eliminate blockage of sensitive anatomical features at an implantation site.

Abstract: A prosthetic apparatus is disclosed including: a tubular stent disposed about a longitudinal axis and extending from a proximal end to a distal end, the stent defining a tubular passage between the ends. The tubular stent has a proximal portion, a distal portion, and a middle portion located between the proximal and distal portions. The proximal and distal portions each comprise a mesh of support struts forming at least one ring of open elements disposed about the longitudinal axis. The middle portion features open regions which reduce or eliminate blockage of sensitive anatomical features at an implantation site.

Abstract: A bio-implant having a length and a proximal and a distal end. The bio-implant includes at least two laminae of dielectric material that are joined together, thereby defining a boundary and that also define a side surface that is intersected by the boundary. The laminae also define a nominal top surface that meets the side surface. At least one set of conductors is interposed between the laminae and extends lengthwise from the proximal end toward the distal end, each one of the set of conductors being terminated at the side surface to form a set of conductor terminations. Additionally, a set of electrode contacts, each is constructed on the side surface and extends over a portion of the nominal top surface, each the electrode contact contacting one of the conductor terminations.

Abstract: An electrolytic current injection device comprising an electrode and an electrolytic current port. In addition a control and rectification assembly is adapted to apply a biphasic pulse to said electrode, yet produce a pulsatile, unidirectional DC electrolytic current at said electrolytic current port. In one preferred embodiment a set of micro machined switches and a refresh electrode are used to maintain the unidirectional DC electrolytic current over time.

Abstract: A finger mounted acoustic sensor. Various embodiments of the finger mounted acoustic sensors include sensors mounted within a casing designed to fit between fingers. The sensor may be rotated with respect to the casing. Other embodiments include mounting tubes for wearing on a finger. Sensors are embedded in the tube and on the rings such that they are easily positioned using technician's fingers. Other embodiments include rings for mounting sensors on and for steadying the sensors. The hand and finger mounted sensors may be used to provide necessary pressure to the sensor and yet provide a sensor that may be manipulated using hand and finger motion. In other embodiments sensors having a local disconnect are disclosed. Such disconnects may be attached to the clothing of a medical professional, attached via a wrist or armband or the like. Various sensor packages may be accompanied by the use of a flat or flex cable to minimize the torque necessary to manipulate the sensor.