Abstract: An indicator arm apparatus includes a mount unit configured to be secured to a vehicle, a first pivotal arm assembly having a first indicator and first hinge unit configured to move the first indicator from a retracted position to a deployed position, a second pivotal arm assembly having a second indicator and second hinge unit configured to move the second indicator from a stored position to an extended position, a first drive unit operably linked to at least one of the pivotal arm assemblies to move the respective indicator between respective positions, and a control unit in operable communication with the first drive unit to provide signals to selectively move at least one indicator. Each hinge unit comprises a pivotally affixed portion that is also affixed to an indicator to pivot the indicator between respective positions.

Abstract: A safety device deployment apparatus includes a housing, a hinge plate pivotally affixed to the housing to pivot around a pin, an actuator linkage assembly having an actuator including a piston, and a crankshaft affixed to the piston through at least a revolute joint and affixed to one of the pin, the hinge plate, and the safety device. The safety device deployment apparatus moves a safety device between a stowed parallel and deployed perpendicular position, relative to the housing, based on extension and retraction of the piston of the actuator. The revolute joint between the piston and crankshaft is disposed in planes on opposite sides of a parallel plane passing through the pin joint based on the extension and retraction of the piston.

Abstract: An indicator arm apparatus includes a mount unit configured to be secured to a vehicle, a first pivotal arm assembly having a first indicator and first hinge unit configured to move the first indicator from a retracted position to a deployed position, a second pivotal arm assembly having a second indicator and second hinge unit configured to move the second indicator from a stored position to an extended position, a first drive unit operably linked to at least one of the pivotal arm assemblies to move the respective indicator between respective positions, and a control unit in operable communication with the first drive unit to provide signals to selectively move at least one indicator. Each hinge unit comprises a pivotally affixed portion that is also affixed to an indicator to pivot the indicator between respective positions.

Abstract: The present disclosure relates methods and compositions useful for prevention of porcine reproductive and respiratory syndrome virus (PRRSv) in animals, including animals of the species Sus scrofa. The present teachings relate to swine wherein at least one allele of a CD163 gene has been inactivated, and to specific methods and nucleic acid sequences used in gene editing to inactivate the CD163 gene. Swine wherein both alleles of the CD163 gene are inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSv).

Abstract: The present disclosure relates methods and compositions useful for prevention of porcine reproductive and respiratory syndrome virus (PRRSv) in animals, including animals of the species Sus scrofa. The present teachings relate to swine wherein at least one allele of a CD163 gene has been inactivated, and to specific methods and nucleic acid sequences used in gene editing to inactivate the CD163 gene. Swine wherein both alleles of the CD163 gene are inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSv). Elite lines comprising homozygous CD163 edited genes retain their superior properties.

Abstract: The present disclosure relates methods and compositions useful for prevention of porcine reproductive and respiratory syndrome virus (PRRSv) in animals, including animals of the species Sus scrofa. The present teachings relate to swine wherein at least one allele of a CD163 gene has been inactivated, and to specific methods and nucleic acid sequences used in gene editing to inactivate the CD163 gene. Swine wherein both alleles of the CD163 gene are inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSv).

Abstract: The present disclosure relates methods and compositions useful for prevention of porcine reproductive and respiratory syndrome virus (PRRSv) in animals, including animals of the species Sus scrofa. The present teachings relate to swine wherein at least one allele of a CD163 gene has been inactivated, and to specific methods and nucleic acid sequences used in gene editing to inactivate the CD163 gene. Swine wherein both alleles of the CD163 gene are inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSv).

Abstract: The present disclosure relates methods and compositions useful for prevention of porcine reproductive and respiratory syndrome virus (PRRSv) in animals, including animals of the species Sus scrofa. The present teachings relate to swine wherein at least one allele of a CD163 gene has been inactivated, and to specific methods and nucleic acid sequences used in gene editing to inactivate the CD163 gene. Swine wherein both alleles of the CD163 gene are inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSv). Elite lines comprising homozygous CD163 edited genes retain their superior properties.

Abstract: The present disclosure relates methods and compositions useful for prevention of porcine reproductive and respiratory syndrome virus (PRRSv) in animals, including animals of the species Sus scrofa. The present teachings relate to swine wherein at least one allele of a CD163 gene has been inactivated, and to specific methods and nucleic acid sequences used in gene editing to inactivate the CD163 gene. Swine wherein both alleles of the CD163 gene are inactivated are resistant to porcine reproductive and respiratory syndrome virus (PRRSv).