Abstract: The present invention provides a novel approach for storing, analyzing, and/or accessing biological data in a cloud computing environment. Sequence data generated by a particular sequencing device may be uploaded to the cloud computing environment during a sequencing run, which reduces the on-site storage needs for the sequence data. Analysis of the data may also be performed in the cloud computing environment, and the instructions for such analysis may be set at the originating sequencing device. The sequence data in the cloud computing environment may be shared according to permissions. Further, the sequence data may be modified or annotated by authorized secondary users.

Abstract: In various embodiments, both very high speed and very high sensitivity hydrogen detection is achieved by controlling water vapor concentration over the catalyst used to convert hydrogen in sample gas (e.g., ambient air) to water vapor, to provide a substantially stable water vapor mixing level at a target mixing ratio. The naturally-occurring water vapor in the sample gas, without further steps, typically would vary over time within a wide range (e.g., due to changing atmospheric conditions). By controlling a level of water vapor over the catalyst to be substantially equal to a target mixing ratio that is not too low as to impair response time, and not too high as to impair sensitivity, both very high speed and very high sensitivity can be provided.

Abstract: Methods, systems, and devices describe bi-triaxial photoconductive switch modules that that eliminate the need for external DC blocking capacitors, while providing a highly compact structure that can produce bipolar output waveforms conducive to feeding to radio-frequency (RF) devices, such as antennas. Some implementations of the disclosed bi-triaxial photoconductive switch modules utilize unified cast-in-place capacitors that can be designed with an appropriate geometry, volume and orientation to provide desired energy storage capacity while eliminating or reducing parasitics.

Abstract: Methods, systems, and devices describe bi-triaxial photoconductive switch modules that that eliminate the need for external DC blocking capacitors, while providing a highly compact structure that can produce bipolar output waveforms conducive to feeding to radio-frequency (RF) devices, such as antennas. Some implementations of the disclosed bi-triaxial photoconductive switch modules utilize unified cast-in-place capacitors that can be designed with an appropriate geometry, volume and orientation to provide desired energy storage capacity while eliminating or reducing parasitics.

Abstract: Methods, systems, and devices describe triaxial photoconductive switch modules that include a center conductor, an inner conductor, an outer conductor, a high voltage capacitor that is formed between the center conductor and the inner conductor, and a photoconductive switch that is formed between the center conductor and a section of the outer conductor. The disclosed triaxial photoconductive switch modules include low inductance current paths that lead to high current efficiencies. Furthermore, the disclosed triaxial photoconductive switch modules eliminate or reduce parasitic capacitance problems of existing systems.

Abstract: A process measurement display is disclosed that includes an indicator configured to change position to indicate a process variable. The display also includes an illumination source configured to provide light to the indicator. The display further includes a processor configured to control the illumination source to provide at least one additional output modality.

Abstract: Methods, systems, and devices describe triaxial photoconductive switch modules that include a center conductor, an inner conductor, an outer conductor, a high voltage capacitor that is formed between the center conductor and the inner conductor, and a photoconductive switch that is formed between the center conductor and a section of the outer conductor. The disclosed triaxial photoconductive switch modules include low inductance current paths that lead to high current efficiencies. Furthermore, the disclosed triaxial photoconductive switch modules eliminate or reduce parasitic capacitance problems of existing systems.

Abstract: Methods, systems, and devices are disclosed for photoconductive switch package configurations. In some aspects, a photoconductive switch package includes of a wide bandgap photoconductive material (e.g., GaN, ZnO, diamond, AlN, SiC, BN, etc.), a source for energetic photons (e.g., a laser), a mechanism to couple the laser into the switch, and a mechanism for high voltage to enter and leave the switch package. In some implementations, the disclosed photoconductive switch packages can be configured as a three terminal device, e.g., similar to transistors, with one of the terminals being laser input or the voltage input to the laser system.

Abstract: Methods, systems, and devices describe triaxial photoconductive switch modules that include a center conductor, an inner conductor, an outer conductor, a high voltage capacitor that is formed between the center conductor and the inner conductor, and a photoconductive switch that is formed between the center conductor and a section of the outer conductor. The disclosed triaxial photoconductive switch modules include low inductance current paths that lead to high current efficiencies. Furthermore, the disclosed triaxial photoconductive switch modules eliminate or reduce parasitic capacitance problems of existing systems.

Abstract: A process measurement display is disclosed that includes an indicator configured to change position to indicate a process variable. The display also includes an illumination source configured to provide light to the indicator. The display further includes a processor configured to control the illumination source to provide at least one additional output modality.

Abstract: Methods, systems, and devices are disclosed for photoconductive switch package configurations. In some aspects, a photoconductive switch package includes of a wide bandgap photoconductive material (e.g., GaN, ZnO, diamond, AlN, SiC, BN, etc.), a source for energetic photons (e.g., a laser), a mechanism to couple the laser into the switch, and a mechanism for high voltage to enter and leave the switch package. In some implementations, the disclosed photoconductive switch packages can be configured as a three terminal device, e.g., similar to transistors, with one of the terminals being laser input or the voltage input to the laser system.

Abstract: Methods, systems, and devices describe triaxial photoconductive switch modules that include a center conductor, an inner conductor, an outer conductor, a high voltage capacitor that is formed between the center conductor and the inner conductor, and a photoconductive switch that is formed between the center conductor and a section of the outer conductor. The disclosed triaxial photoconductive switch modules include low inductance current paths that lead to high current efficiencies. Furthermore, the disclosed triaxial photoconductive switch modules eliminate or reduce parasitic capacitance problems of existing systems.

Abstract: A photoconductive switch having a wide bandgap semiconductor material substrate between opposing electrodes, with one of the electrodes having an aperture or apertures at an electrode-substrate interface for transversely directing radiation therethrough from a radiation source into a triple junction region of the substrate, so as to geometrically constrain the conductivity path to within the triple junction region.

Abstract: A photoconductive switch and optical transconductance varistor having a photoconductive region e.g. a wide bandgap semiconductor material substrate between opposing electrodes. An optical waveguide is arranged to surround the photoconductive region for directing conduction-inducing radiation into the photoconductive region. And an optical diffusion element is arranged to diffuse/disperse the radiation prior to entering the optical waveguide and into the substrate, for uniformly illuminating the substrate for conduction.

Abstract: A method includes determining an operational parameter of a first vehicle traveling with a plurality of vehicles in a transportation network and/or a route in the transportation network, identifying a failure condition of the first vehicle and/or the route based on the operational parameter, obtaining plural different sets of remedial actions that dictate operations to be taken based on the operational parameter, simulating travel of the plurality of vehicles in the transportation network based on implementation of the different sets of remedial actions, determining potential consequences on travel of the plurality of vehicles in the transportation network when the different sets of remedial actions are implemented in the travel that is simulated, and based on the potential consequences, receiving a selection of at least one of the different sets of remedial actions to be implemented in actual travel of the plurality of vehicles in the transportation network.

Abstract: A photoconductive switch having a wide bandgap semiconductor material substrate between opposing electrodes, with one of the electrodes having an aperture or apertures at an electrode-substrate interface for transversely directing radiation therethrough from a radiation source into a triple junction region of the substrate, so as to geometrically constrain the conductivity path to within the triple junction region.

Abstract: A photoconductive switch having a wide bandgap semiconductor material substrate between opposing electrodes, with one of the electrodes having an aperture or apertures at an electrode-substrate interface for transversely directing radiation therethrough from a radiation source into a triple junction region of the substrate, so as to geometrically constrain the conductivity path to within the triple junction region.

Abstract: A multi-level system for management of a railway system and its operational components in which the railway system has a first level configured to optimize an operation within the first level that includes first level operational parameters which define operational characteristics and data of the first level, and a second level configured to optimize an operation within the second level that includes second level operational parameters which define the operational characteristic and data of the second level. The first level provides the second level with the first level operational parameters, and the second level provides the first level with the second level operational parameters, such that optimizing the operation within the first level and optimizing the operation within the second level are each a function of optimizing a system optimization parameter. The levels can include a railroad infrastructure level, a track network level, a train level, a consist level and a locomotive level.

Abstract: A detachable beverage container handle includes a reusable figurine-shaped handle which can be mounted and released from beverage contains of a plurality of container diameters. The figurine is hinged to accommodate containers of different sizes. A lower extremity of the figurine includes a clamp for engaging the base or bottom of the container. an upper extremity of the figurine has a clamp for engaging the rim of the container. An embodiment of the handle has a rim clamp with pivoting arms that force gripping surfaces of the clamp into an engaging position on the rim. A user may pivot the arms to a release position.

Abstract: A bipolar electrosurgical instrument has a pair of pivotable juxtaposed jaw members and a locking mechanism operatively associated with a second of the jaw members. The locking mechanism has a first position engaged with the second jaw member for preventing movement of the second jaw member between an axially aligned orientation and at least one angled orientation, and a second position. The second position is disengaged from the second jaw member allowing for movement of the second jaw member between the axially aligned orientation and the at least one angled orientation. The instrument has an actuation mechanism operatively connected to a first of the jaw members with the actuation mechanism operable to move the first jaw member between an axially aligned first orientation and at least one angled orientation. An articulation knob is operatively associated with the locking mechanism and effectuates independent operation of the locking and actuation mechanisms.