Patents by Inventor Scott D. Power

Scott D. Power has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190048378
    Abstract: Described are compositions and methods relating to cellulase/hemicellulase enzyme blends for improving the enzymatic hydrolysis of cellulosic and hemicellulosic materials, as commonly found in biomass.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 14, 2019
    Inventors: SCOTT D POWER, SUZANNE E. LANTZ, EDMUND A. LARENAS, ROBERT M. CALDWELL
  • Patent number: 9803181
    Abstract: Hybrid alpha-amylases are provided that share a conserved 3D structure in whole or in part with a wild-type Termamyl-like ?-amylase, e.g., a Bacillus amylase. In the hybrid, an N-terminal portion of a Termamyl-like ?-amylase is replaced with sequences from an archae ?-amylase. The sequence similarity between the two amylase sequences may be less than 60%. Conserving the wild-type 3D structure in the hybrid facilitates obtaining enzymatically active amylases. In one embodiment, one or both amylase sequences contribute residues to the B domain, resulting in particularly advantageous properties. For instance, replacement of the Ca2+ binding site in the B domain of the Termamyl-like ?-amylase with a B domain sequence of an archae ?-amylase that does not bind Ca2+ can produce a hybrid that is fully active in the absence of Ca2+.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: October 31, 2017
    Assignee: Danisco US Inc.
    Inventors: Scott D. Power, Andrew Shaw
  • Publication number: 20170306360
    Abstract: The present invention provides a method for producing an alcohol comprising: (a) admixing a tripeptidyl peptidase, predominantly having exopeptidase activity, with a feedstock or a fraction thereof before, during or after fermentation of said feedstock or a fraction thereof; and (b) recovering an alcohol. Also provided are uses of a tripeptidyl peptidase and by-products of alcohol production obtainable by the method of the invention.
    Type: Application
    Filed: October 23, 2015
    Publication date: October 26, 2017
    Applicant: DANISCO US INC.
    Inventors: Andrei MIASNIKOV, Maria MA, Scott D. POWER
  • Publication number: 20160244699
    Abstract: The present teachings provide an improved granule comprising a clay layer. The granules can be used in a variety of contexts, including automatic dish washing applications. Methods of making and using are also provided.
    Type: Application
    Filed: October 14, 2014
    Publication date: August 25, 2016
    Applicant: Danisco US Inc.
    Inventors: Rajdeep S. Dhaliwal, Douglas A. Dale, Scott D. Power
  • Patent number: 9303254
    Abstract: Chimeric alpha-amylases having the characteristics of high thermostability and good performance in starch degradation, especially high-temperature liquefaction processes, are provided. The alpha-amylases are chimeras of AmyL and AmyS enzymes, and are useful in starch degradation processes. Methods of making the chimeric enzymes, and methods of using the chimeric alpha-amylases for liquefaction, cleaning starch residue from a surface, and treating woven material to remove coatings. Kits for practicing the methods are provided. Polynucleotides encoding the chimeric amylases, vectors, and expression hosts also are provided.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: April 5, 2016
    Assignee: Danisco US Inc.
    Inventors: Scott D. Power, Andrew Shaw
  • Publication number: 20160060665
    Abstract: Described are compositions and methods relating to cellulase/hemicellulase enzyme blends for improving the enzymatic hydrolysis of cellulosic and hemicellulosic materials, as commonly found in biomass.
    Type: Application
    Filed: June 30, 2015
    Publication date: March 3, 2016
    Applicant: DANISCO US INC.
    Inventors: Scott D. POWER, Robert M. CALDWELL, Suzanne E. LANTZ, Edmund A. LARENAS
  • Publication number: 20160010129
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Application
    Filed: June 17, 2015
    Publication date: January 14, 2016
    Inventors: William A. Cuevas, Sang-Kyu Lee, Sandra W. Ramer, Andrew Shaw, Amr R. Toppozada, David A. Estell, Louise Wallace, Regina Chin, Carol A. Requadt, Scott D. Power, Michael J. Pepsin
  • Patent number: 9090887
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: July 28, 2015
    Assignee: DANISCO US INC.
    Inventors: William A Cuevas, Sang-Kyu Lee, Sandra W Ramer, Andrew Shaw, Amr R Toppozada, David E Estell, Louise Wallace, Regina Chin, Carol A Requadt, Scott D Power, Michael J Pepsin
  • Patent number: 9084734
    Abstract: The present invention provides peptides and supported peptides for treating various diseases and conditions. In particularly preferred embodiments, the present invention provides compositions and methods for personal care. In some embodiments the present invention provides compositions for use in skin and/or hair care, as well as cosmetic compositions. IN alternative particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold protein comprises BBI.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: July 21, 2015
    Assignee: Danisco US Inc.
    Inventors: Katherine D. Collier, Anthony Day, Hans de Nobel, David A. Estell, Grant C. Ganshaw, Marc Kolkman, Raj Lad, Jeffrey V. Miller, Christopher J. Murray, Scott D. Power, Brian Schmidt, Anita van Kimmenade, Gudrun Vogtentanz
  • Patent number: 9040278
    Abstract: An ?-amylase from Bacillus subtilis (AmyE) produces significant amounts of glucose from various carbohydrate substrates, including vegetable starch, maltoheptaose, and maltotriose. Among other things, this advantageous property allows AmyE or variants thereof to be used in a saccharification reaction having a reduced or eliminated requirement for glucoamylase. The reduction or elimination of the glucoamylase requirement significantly improves the efficiency of the production of ethanol or high fructose corn syrup, for example.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: May 26, 2015
    Assignee: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, Regina Chin, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Michael J. Pepsin, Scott D. Power, Sandra W. Ramer, Carol A. Requadt, Andrew Shaw, Amr R. Toppozada, Louise Wallace
  • Patent number: 8975056
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: March 10, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Scott D. Power, Sandra W. Ramer, Amr Toppozada, Louise Wallace
  • Patent number: 8962796
    Abstract: The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: February 24, 2015
    Assignee: Danisco US Inc.
    Inventors: Neelam S. Amin, Katherine D. Collier, Melodie Estabrook, David A. Estell, Bryan P. Fox, Scott D. Power, Brian F. Schmidt, Gudrun Vogentanz
  • Publication number: 20150017701
    Abstract: Hybrid alpha-amylases are provided that share a conserved 3D structure in whole or in part with a wild-type Termamyl-like ?-amylase, e.g., a Bacillus amylase. In the hybrid, an N-terminal portion of a Termamyl-like ?-amylase is replaced with sequences from an archae ?-amylase. The sequence similarity between the two amylase sequences may be less than 60%. Conserving the wild-type 3D structure in the hybrid facilitates obtaining enzymatically active amylases. In one embodiment, one or both amylase sequences contribute residues to the B domain, resulting in particularly advantageous properties. For instance, replacement of the Ca2+ binding site in the B domain of the Termamyl-like ?-amylase with a B domain sequence of an archae ?-amylase that does not bind Ca2+ can produce a hybrid that is fully active in the absence of Ca2+.
    Type: Application
    Filed: July 25, 2014
    Publication date: January 15, 2015
    Applicant: DANISCO US INC.
    Inventors: Scott D. Power, Andrew Shaw
  • Patent number: 8841107
    Abstract: Hybrid alpha-amylases are provided that share a conserved 3D structure in whole or in part with a wild-type Termamyl-like ?-amylase, e.g., a Bacillus amylase. In the hybrid, an N terminal portion of a Termamyl-like ?-amylase is replaced with sequences from an archae ? amylase. The sequence similarity between the two amylase sequences may be less than 60%. Conserving the wild-type 3D structure in the hybrid facilitates obtaining enzymatically active amylases. In one embodiment, one or both amylase sequences contribute residues to the B domain, resulting in particularly advantageous properties. For instance, replacement of the Ca2+ binding site in the B domain of the Termamyl-like ?-amylase with a B domain sequence of an archae ? amylase that does not bind Ca2+ can produce a hybrid that is fully active in the absence of Ca2+.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: September 23, 2014
    Assignee: Danisco US Inc.
    Inventors: Scott D. Power, Andrew Shaw
  • Publication number: 20140106409
    Abstract: Chimeric alpha-amylases having the characteristics of high thermostability and good performance in starch degradation, especially high-temperature liquefaction processes, are provided. The alpha-amylases are chimeras of AmyL and AmyS enzymes, and are useful in starch degradation processes. Methods of making the chimeric enzymes, and methods of using the chimeric alpha-amylases for liquefaction, cleaning starch residue from a surface, and treating woven material to remove coatings. Kits for practicing the methods are provided. Polynucleotides encoding the chimeric amylases, vectors, and expression hosts also are provided.
    Type: Application
    Filed: September 26, 2013
    Publication date: April 17, 2014
    Applicant: Danisco US Inc.
    Inventors: Scott D. Power, Andrew Shaw
  • Patent number: 8512982
    Abstract: The present invention relates to cells that have been genetically manipulated to have an altered capacity to express and/or produce proteins of interest. In particular, the present invention relates to modified host cells of Gram-positive microorganisms, such as Bacillus species that are capable of overexpressing ymaH. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode YmaH, and the modified host cells comprising them. In particular, the present invention relates to compositions and methods of overexpressing YmaH for enhancing the expression and production of proteins of interest (e.g., proteases) in Bacillus species.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: August 20, 2013
    Assignee: Danisco US Inc.
    Inventors: Marguerite A. Cervin, Eugenio Ferrari, Scott D. Power
  • Patent number: 8507244
    Abstract: Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased thermostability, reduced calcium dependence, increased washing/cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: August 13, 2013
    Assignee: Danisco US Inc.
    Inventors: Andrew Shaw, Sandra Ramer, Scott D. Power, Claudine Chang, Melodie Estabrook, Brian E. Jones, Clement Choy, Marc Kolkmam, Chris Leeflang, Casper Vroeman, Walter Weyler, Karsten Kraugh, Mansi Goyal, Thomas Graycar, Victoria Huang
  • Publication number: 20130065829
    Abstract: The present invention provides peptides and supported peptides for treating proliferative diseases. In particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold protein is BBI.
    Type: Application
    Filed: September 10, 2012
    Publication date: March 14, 2013
    Applicant: Danisco US Inc.
    Inventors: Anthony G. Day, David A. Estell, Christopher J. Murray, Scott D. Power
  • Patent number: 8394941
    Abstract: The present invention relates to modified variant Bowman Birk Protease Inhibitor proteins (BBPIs) that comprise peptides that bind target proteins, and that are further modified to have greater protease inhibitory activity and/or be produced at greater yields than the unmodified BBPIs. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode the modified variant BBPIs, the transformed host cells that express and produce the modified variant BBPIs, the modified variant BBPI proteins, the compositions comprising the modified variant BBPIs, and the methods for making and using the modified variant BBPIs in personal care.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: March 12, 2013
    Assignee: Danisco US Inc.
    Inventors: Neelam S. Amin, Katherine D. Collier, Melodie Estabrook, David A. Estell, Bryan P. Fox, Scott D. Power, Brian F. Schmidt, Gudrun Vogtentanz
  • Publication number: 20130011882
    Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
    Type: Application
    Filed: May 15, 2012
    Publication date: January 10, 2013
    Applicant: DANISCO US INC.
    Inventors: LUIS G. CASCÃO-PEREIRA, JAMES T. KELLIS, JR., BRADLEY A. PAULSON, SCOTT D. POWER, SANDRA W. RAMER, VIVEK SHARMA, ANDREW SHAW, JAYARAMA K. SHETTY, DONALD E. WARD