Abstract: A wearable biosensing device features a first housing and biosensing logic. The first housing includes a housing element and a deformable stiffening element inserted within the housing element. The housing element includes a plurality of lobes formed with a corresponding plurality of cavities. The biosensing logic is inserted into the plurality of cavities, wherein an electronics assembly is positioned within a first lobe of the plurality of lobes, a sensing assembly is positioned within a second lobe, and an interconnect for communicative coupling of the electronics assembly and the sensing assembly is positioned within a third lobe of the plurality of lobes. The forces applied by at least the first housing and the biosensing logic are balanced by the deformable stiffening element.

Abstract: A system and method for monitoring respiration including sensing a signal that varies with respiration, deriving a respiration parameter, applying criteria for detecting a respiration disturbance and determining one or more respiratory disturbance metrics. The system preferably includes an implantable sensor with an associated implantable medical device such that chronic respiration monitoring is possible. The implantable medical device may execute methods for detecting and measuring respiratory disturbances or may store data to be transferred to an external device for detecting and measuring respiratory disturbances. Respiratory disturbance detection may trigger a responsive action such as physiological data storage, a change in therapy delivery, or a clinician warning. Assessment of cardiac function may be made based on metrics of respiratory disturbances or a measure of circulatory delay time following detection of a respiratory disturbance.

Abstract: An implantable device having enhanced capabilities for monitoring a patient's heart rate and respiration trends over extended periods of time is disclosed. The information collected by the implantable device may be stored and telemetered to an associated external device such as a device programmer for display and analysis. Heart rates are measured by measuring the time intervals between sensed depolarizations of a chamber of the patient's heart and preceding sensed depolarizations or delivered pacing pulses. Intervals may be measured in the ventricle and/or atrium of the patient's heart. According to another aspect of the invention, an implanted impedance sensor is employed to monitor minute ventilation. The heart rate and minute ventilation data is used to develop long-term trend data used for diagnostic purposes. In one embodiment of the invention, heart interval and minute ventilation measurements are taken only during defined time periods of the night and/or day when the patient is at rest.