Patents by Inventor Scott Dax

Scott Dax has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Ureas and Methods of Making and Using Same
    Publication number: 20220315567
    Abstract: The invention relates to substituted ureas, and compositions comprising the same, which in certain embodiments are useful for treating and/or preventing pain in a subject in need thereof.
    Type: Application
    Filed: November 5, 2021
    Publication date: October 6, 2022
    Inventors: Brett A. Tounge, Shariff Bayoumy, Lawrence C. Kuo, Scott Dax
  • Substituted ureas and methods of making and using same
    Patent number: 11198685
    Abstract: The invention relates to substituted ureas, and compositions comprising the same, which in certain embodiments are useful for treating and/or preventing pain in a subject in need thereof.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: December 14, 2021
    Assignee: Mebias Discovery, Inc.
    Inventors: Brett A. Tounge, Shariff Bayoumy, Lawrence C. Kuo, Scott Dax
  • Substituted Ureas and Methods of Making and Using Same
    Publication number: 20200308155
    Abstract: The invention relates to substituted ureas, and compositions comprising the same, which in certain embodiments are useful for treating and/or preventing pain in a subject in need thereof.
    Type: Application
    Filed: May 18, 2020
    Publication date: October 1, 2020
    Inventors: Brett A. Tounge, Shariff Bayoumy, Lawrence C. Kuo, Scott Dax
  • Substituted ureas and methods of making and using same
    Patent number: 10683283
    Abstract: The invention relates to substituted ureas, and compositions comprising the same, which in certain embodiments are useful for treating and/or preventing pain in a subject in need thereof.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: June 16, 2020
    Assignee: MEBIAS DISCOVERY, INC.
    Inventors: Brett A. Tounge, Shariff Bayoumy, Lawrence C. Kuo, Scott Dax
  • SUBSTITUTED UREAS AND METHODS OF MAKING AND USING SAME
    Publication number: 20190194178
    Abstract: The invention relates to substituted ureas, and compositions comprising the same, which in certain embodiments are useful for treating and/or preventing pain in a subject in need thereof.
    Type: Application
    Filed: August 31, 2017
    Publication date: June 27, 2019
    Inventors: BRETT A. TOUNGE, SHARIFF BAYOUMY, LAWRENCE C. KUO, SCOTT DAX
  • Breathing control modulating compounds, and methods of using same
    Patent number: 9643971
    Abstract: The present invention includes pyrimido[5,4-d]pyrimidines that are useful in the prevention and/or treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of preventing and/or treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of at least one compound of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of at least one compound of the invention.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: May 9, 2017
    Assignee: Galleon Pharmaceuticals, Inc.
    Inventors: Scott Dax, James Joseph Mencel, Vita Ozola, Kirill Shubin, Marina Martjuga, Edgars Suna
  • NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF USING SAME
    Publication number: 20160046635
    Abstract: The present invention includes pyrimido[5,4-d]pyrimidines that are useful in the prevention and/or treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of preventing and/or treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of at least one compound of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of at least one compound of the invention.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 18, 2016
    Inventors: SCOTT DAX, JAMES JOSEPH MENCEL, VITA OZOLA, KIRILL SHUBIN, MARINA MARTJUGA, EDGARS SUNA
  • Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
    Patent number: 8415341
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, r, R2 and Z are defined herein.
    Type: Grant
    Filed: April 22, 2010
    Date of Patent: April 9, 2013
    Assignee: Janssen Pharmaceutica, NV
    Inventors: Kristen Chevalier, Jose Clemente, Scott Dax, Chris Flores, Li Liu, Mark Macielag, Mark McDonnell, Marina Nelen, Erica Nulton, Stephen Prouty, Matthew Todd, Sui-Po Zhang, Bin Zhu
  • Analgesic Compounds, Compositions and Uses Thereof
    Publication number: 20120202860
    Abstract: The invention relates to compounds, compositions, and methods for diminishing pain in a subject in need thereof comprising administering the compounds and compositions herein described.
    Type: Application
    Filed: March 8, 2011
    Publication date: August 9, 2012
    Applicant: Galleon Pharmaceuticals, Inc.
    Inventors: James Mannion, Scott Dax
  • HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS
    Publication number: 20100324015
    Abstract: Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, r, R2 and Z are defined herein.
    Type: Application
    Filed: April 22, 2010
    Publication date: December 23, 2010
    Inventors: Kristen Chevalier, Jose Clemente, Scott Dax, Chris Flores, Li Liu, Mark Macielag, Mark McDonnell, Marina Nelen, Erica Nulton, Stephen Prouty, Matthew Todd, Sui-Po Zhang, Bin Zhu
  • TRICYCLIC-BRIDGED PIPERIDINYLIDENE DERIVATIVES AS DELTA OPIOID MODULATORS
    Publication number: 20090291979
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases and conditions, including pain. Such compounds are represented by Formula I as follows: wherein A, G, Y, R3, R4, and R5 are defined herein.
    Type: Application
    Filed: May 22, 2009
    Publication date: November 26, 2009
    Inventors: Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic-bridged piperidinylidene derivatives as ?-opioid modulators
    Patent number: 7553850
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases and conditions, including pain. Such compounds are represented by Formula I as follows: wherein A, G, Y, R3, R4, and R5 are defined herein.
    Type: Grant
    Filed: August 2, 2005
    Date of Patent: June 30, 2009
    Assignee: Janssen Pharmaceutica NV
    Inventors: Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • AMINOTETRALIN-DERIVED UREA MODULATORS OF VANILLOID VR1 RECEPTOR
    Publication number: 20080097102
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to ?-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Application
    Filed: October 23, 2007
    Publication date: April 24, 2008
    Inventors: Ellen Codd, Scott Dax, Michele Jetter, Mark McDonnell, James McNally, Mark Youngman
  • COLD MENTHOL RECEPTOR-1 ANTAGONISTS
    Publication number: 20080027029
    Abstract: The invention is directed to TRPM8 antagonists of Formula (I). More specifically, the present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and methods for treating TRPM8-mediated disorders. Pharmaceutical and veterinary compositions and methods of treating pain and various other disease states or conditions using compounds of the invention are also described.
    Type: Application
    Filed: May 9, 2007
    Publication date: January 31, 2008
    Inventors: Raymond Colburn, Scott Dax, Christopher Flores, Jay Matthews, Ning Qin, Laura Reany, Christopher Teleha, Mark Youngman
  • Biaryl derived amide modulators of vanilloid VR1 receptor
    Publication number: 20060223837
    Abstract: The invention is directed to novel vanilloid receptor type 1 (VR1) ligands. More specifically, the invention relates to novel biaryl-derived amides that are potent antagonists or agonists of VR1. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: March 23, 2006
    Publication date: October 5, 2006
    Inventors: Ellen Codd, Scott Dax, Christopher Flores, Michelle Jetter, Mark Youngman
  • Tricyclic delta-opioid modulators
    Publication number: 20060148823
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: January 5, 2006
    Publication date: July 6, 2006
    Inventors: Steven Coats, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060135763
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: Steve Coats, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060135522
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: John Carson, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060135524
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: John Carson, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Amine and amide derivatives as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders
    Publication number: 20060052388
    Abstract: Amine and amide derivatives of the formula: which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing amines and amides of formula A as the active ingredient are described. The amines and amides of formula A are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.
    Type: Application
    Filed: October 5, 2005
    Publication date: March 9, 2006
    Inventors: Scott Dax, James McNally, Mark Youngman