Patents by Inventor Scott E. Fishman

Scott E. Fishman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing the antibiotic-producing ability of antibiotic-producing microorganisms
    Patent number: 5672497
    Abstract: A method for increasing the antibiotic-producing ability of an antibiotic-producing microbial host cell is disclosed. The method involves transforming an antibiotic-producing microorganism with a recombinant DNA cloning vector that codes for the expression of an antibiotic biosynthetic enzyme or other gene product. The gene preferably codes for a product that is rate-limiting in the antibiotic biosynthetic pathway in Streptomyces. Plasmids that are useful for increasing tylosin production in accordance with the present method include plasmids pHJL280, pHJL284, pHJL309, pHJL311, and pHJL315. The invention further comprises microorganisms transformed with plasmids pHJL280, pHJL284, pHJL309, pHJL311, and pHJL315 and also other microorganisms and vectors used in accordance with the present method.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: September 30, 1997
    Assignee: Eli Lilly and Company
    Inventors: Karen L. Cox, Scott E. Fishman, Charles L. Hershberger, Eugene T. Seno