Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR6 or N; Y is CR3 or N; R1, R2, R3, R4, R5, R6, R7, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.

Abstract: Flow control devices herein have a housing defining a plurality of parallel conduits. The first conduit has a normally closed check valve defined to open under a first preselected pressure differential controlling flow through the first conduit in a first direction of flow. The second conduit has a normally neutral check valve defined to open under a second preselected pressure differential in a second direction of flow that is opposite the first direction of flow. The third conduit defines a restriction profile, i.e., has a restrictor, having a third preselected pressure differential. The flow control devices are included as part of an engine system, more specifically a crankcase ventilation breach detection system.

Abstract: Multifunction end effector apparatus and methods for assembling thermoplastic composite articles are disclosed. An example apparatus for assembling a thermoplastic composite article includes a robot and an end effector coupled to the robot. The end effector includes a cutting head, a vacuum head, and a welding head.

Abstract: Flow control devices herein have a housing defining a plurality of parallel conduits. The first conduit has a normally closed check valve defined to open under a first preselected pressure differential controlling flow through the first conduit in a first direction of flow. The second conduit has a normally neutral check valve defined to open under a second preselected pressure differential in a second direction of flow that is opposite the first direction of flow. The third conduit defines a restriction profile, i.e., has a restrictor, having a third preselected pressure differential. The flow control devices are included as part of an engine system, more specifically a crankcase ventilation breach detection system.

Abstract: Multifunction end effector apparatus and methods for assembling thermoplastic composite articles are disclosed. An example apparatus for assembling a thermoplastic composite article includes a robot and an end effector coupled to the robot. The end effector includes a cutting head, a vacuum head, and a welding head.

Abstract: The invention provides a method of increasing protein production in a cell by contacting the cell with miRNA, siRNA or a combination thereof, or increasing protein production by genome editing methodologies to silence or inhibit gene expression. A screening method for obtaining such miRNA or siRNA species is also provided, as well as identification of target genes for genome editing.

Abstract: A simulated real-time environment employs a plurality of computer controlled video projectors and screens at least fore and aft of a participant-trainee to present life-size displays mutually coordinated to represent views of a same environment from a participant's perspective, each screen representing the participant's view looking in a different direction. In response to a participant's actions, the computer seamlessly changes a projected video to match the participant' actions and maintain a scenario consistent between the two screens. The participant uses a light-emitting simulated firearm or his own firearm loaded with a light-emitting cartridge and/or other equipment with which he is familiar, such as a modified or simulated flashlight, taser, chemical spray container or the like, tethered or untethered by a communication wire, to respond to a simulated situation, which response detected and interpreted by the computer to direct a branch in the projected videos and even shoot back a simulated bullet.

Abstract: A simulated real-time environment employs a plurality of computer controlled video projectors and screens at least fore and aft of a participant-trainee to present life-size displays mutually coordinated to represent views of a same environment from a participant's perspective, each screen representing the participant's view looking in a different direction. In response to a participant's actions, the computer seamlessly changes a projected video to match the participant' actions and maintain a scenario consistent between the two screens. The participant uses a light-emitting simulated firearm or his own firearm loaded with a light-emitting cartridge and/or other equipment with which he is familiar, such as a modified or simulated flashlight, taser, chemical spray container or the like, tethered or untethered by a communication wire, to respond to a simulated situation, which response detected and interpreted by the computer to direct a branch in the projected videos and even shoot back a simulated bullet.

Abstract: A door control apparatus useable in buildings or other facilities having many locked doors or rooms and requiring controlled access to the rooms, utilizes paging transmitters and paging receivers to transmit information from a central control system to individual door control units located at each controlled door. The door control unit may include a card reader for reading an entry card. Card identification information is transmitted wirelessly from a main paging transmitter connected with the control system and is received by the door control units at selected doors to define the card or cards which are to be accepted at each door control unit to open a controlled door. The invention also allows all or selected doors to be unlocked by a transmitted command from the control system to allow fast entry through such doors to fire crews or other emergency personnel. The door control unit may also transmit data to the control system using paging technology.

Abstract: A method and apparatus for a guest having a valid general purpose credit card to register at a place of lodging having a computer, and which uses the general purpose credit card as a key to the assigned room. The method involves the inserting of a general purpose credit card into a card reader of a guest accessible registration terminal, the card reader reading the credit card information and delivering the information to a computer. The computer stores the card information, and the terminal, by means of registration software obtains further information from the guest, assigns the guest a room, and informs the guest of the room assignment, after which the credit card becomes a key to the guest room. When the credit card is inserted in the proper card reader at the assigned guest room door, the computer will actuate the lock and allow the guest access.