Abstract: A bone screw for treating a bone fracture having a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body. The bone screw may also include a plunger assembly having a plunger with a threaded portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body.

Abstract: A bone fixation member used to promote healing of a fracture. The fixation member having an upper surface, a lower surface, and an aperture extending between the upper surface and the lower surface. The aperture including a plurality of upper protrusions and a plurality of lower protrusions. The upper protrusions spaced longitudinally from the lower protrusions wherein the lower protrusions are out of phase with the upper protrusions. In a further example, the upper protrusions are spaced circumferentially in a common plane and the lower protrusions are spaced circumferentially in a common plane. The common plane of the upper protrusions spaced from the common plane of the lower protrusions along a longitudinal axis of the aperture with the aperture lacking protrusions between the plane of upper protrusions and plane of lower protrusions.

Abstract: A bone fixation member used to promote healing of a fracture. The fixation member having an upper surface, a lower surface, and an aperture extending between the upper surface and the lower surface. The aperture including a plurality of upper protrusions and a plurality of lower protrusions. The upper protrusions spaced longitudinally from the lower protrusions wherein the lower protrusions are out of phase with the upper protrusions. In a further example, the upper protrusions are spaced circumferentially in a common plane and the lower protrusions are spaced circumferentially in a common plane. The common plane of the upper protrusions spaced from the common plane of the lower protrusions along a longitudinal axis of the aperture with the aperture lacking protrusions between the plane of upper protrusions and plane of lower protrusions.

Abstract: A bone screw for treating a bone fracture having a plunger assembly and a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The plunger assembly includes a threaded engagement portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body.

Abstract: A bone screw for treating a bone fracture having a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body. The bone screw may also include a plunger assembly having a plunger with a threaded portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body.

Abstract: A bone screw for treating a bone fracture having a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body. The bone screw may also include a plunger assembly having a plunger with a threaded portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body.

Abstract: A bone screw for treating a bone fracture having a plunger assembly and a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The plunger assembly includes a threaded engagement portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body.

Abstract: A bone plate for treating clavicle fractures. The bone plate may include an elongated body having one or more curved portions that roughly conform to the surface and/or anatomical curvature of the clavicle. One or more openings may be provided for receiving an anchoring member, such as a bone screw, for fastening at least a portion of the bone plate onto the clavicle. The bone plate may provide at least one rail member extending along a portion of the body of the bone plate. The bone plate, when affixed to the clavicle, permits the rail member to rest upon the outer surface of the clavicle, thus providing an area defining a cavity formed between an outer surface of the clavicle and a bottom surface of the body of the bone plate, and thus allowing blood to circulate against and around the clavicle.

Abstract: Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot.

Abstract: Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape-retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot.

Abstract: Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality.

Abstract: Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape-retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot.

Abstract: Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot.

Abstract: A pledget is provided for use with a surgical staple having a plurality of prongs. The pledget includes a central region that is configured to be retained adjacent to a wound site by the surgical staple. The pledget may promote hemostasis by stemming the flow of blood from a wound that is being closed by the staple. Additionally, the pledget may be provided including physiologically active agents that may inhibit infection, promote extraluminal clotting, and inhibit intraluminal clotting.