Abstract: An anti-fogging facemask for preventing fogging of the wearer's glasses or goggles is described herein. The anti-fogging facemask includes an outer facemask and an inner facemask. The inner facemask is attached to the outer facemask. The inner facemask provides a barrier to prevent exhaled air from traveling through the upper end of the facemask. The inner facemask directs exhaled air downwards. The outer facemask forms a seal at an upper portion of the wearer's nose. The facemask may be configured to serve as a CO2 concentrating mask for temporary relief of allergic rhinitis symptoms.

Abstract: An anti-fogging facemask for preventing fogging of the wearer's glasses or goggles may be described herein. The anti-fogging facemask include an outer facemask and an inner facemask. The inner facemask is attached to the outer facemask. The inner facemask provides a barrier to prevent exhaled air from traveling through the upper end of the facemask. The inner facemask directs exhaled air downwards. The outer facemask forms a seal at an upper portion of the wearer's nose.

Abstract: An ocular device for insertion into the eye (for example, into a lacrimal punctum or a conjunctival sac) are described herein. The ocular device may continuously capture specific analytes from tear fluid. Several embodiments of the ocular device may have one or more open channels and pores that enable tears to drain naturally through while capturing specific analytes. A mechanism of detecting analytes in bodily fluids using materials comprised of DNAzymes and/or aptamers are described herein. Aptamers are oligonucleotide or peptide molecules that bind to a specific target molecule. DNAzymes are designed to catalyze a number of biological reactions (i.e., RNA cleavage, DNA cleavage, ligation, or phosphorylation reactions). A number of ways an ocular insert may capture analytes in tear fluid in vivo for subsequent in vitro analysis are described herein. Additionally, a specific mechanism for colorimetric detection of analytes using aptamer- and/or DNAzyme-crosslinked hydrogels are described herein.

Abstract: A method for delivering catheters, and stents composed of soft, compliant polymers through anatomical passages. These devices have a bulbous anchorage end with a diameter greater than the rest of the catheter. To facilitate implant and delivery a pusher catheter or sheath with an internal lumen larger than the outer diameter of the catheter but smaller than the outer diameter of the bulbous anchorage end. The distal end of pusher catheter or the sheath physically engages the proximal end of the bulbous anchorage end and applies an axial force to coaxially advance the catheter over a guidewire though anatomical passages. This method allows a physician to move the catheter to an anatomical site without the device exhibiting buckling due to axial force applied. Similarly, this delivery method will allow more force to be applied to the distal end of the catheter diminishing the likelihood of buckling.

Abstract: The present invention relates generally a manufacturing process which results in a completely hydrogel polymer device that maintains lumen patency which allows for numerous applications. Catheters and stents are particular examples, and their composition, mechanical characteristics, and the significantly unique ability to conduct and allow fluids to pass from one end to the other without physiological rejection, inflammation, or manifestation of complications due to implant or otherwise undesirable outcomes when used for ambulatory and or therapeutic interventions is the purpose of the invention.

Abstract: Devices, systems and methods for providing energy to treat large areas of tissue. Several embodiments of the devices control resistance or other parameters to provide substantially uniform current density along a length of tissue with reduced edge effects.

Abstract: The present invention relates generally a manufacturing process which results in a completely hydrogel polymer device that maintains lumen patency which allows for numerous applications. Catheters and stents are particular examples, and their composition, mechanical characteristics, and the significantly unique ability to conduct and allow fluids to pass from one end to the other without physiological rejection, inflammation, or manifestation of complications due to implant or otherwise undesirable outcomes when used for ambulatory and or therapeutic interventions is the purpose of the invention.